Details of Drug

Drug General Information (ID: D0436)
Drug Name	Deflazacort
Drug Type	Small molecule
Drug Synonymous	C25H33NO6; Deflazacort (Calcort); Deflazacortum [INN-Latin]; EINECS 238-483-7; Deflan (TN); D09WYX; AC1L1BQ2; Deflazacort [USAN:BAN:INN]; CTK8F9001; MolPort-035-394-927 Click to Show/Hide
Disease Class	8C70: Muscular dystrophy
Therapeutic Class	Glucocorticoids
Structure
Structure	3D Structure		2D Structure
Formula	C25H31NO6
InChI	1S/C25H31NO6/c1-13-26-25(20(30)12-31-14(2)27)21(32-13)10-18-17-6-5-15-9-16(28)7-8-23(15,3)22(17)19(29)11-24(18,25)4/h7-9,17-19,21-22,29H,5-6,10-12H2,1-4H3/t17-,18-,19-,21+,22+,23-,24-,25+/m0/s1
InChIKey	FBHSPRKOSMHSIF-GRMWVWQJSA-N
Canonical SMILES	CC1=NC2(C(O1)CC3C2(CC(C4C3CCC5=CC(=O)C=CC45C)O)C)C(=O)COC(=O)C
External Link
	Pubchem ID	189821
	CAS Number	14484-47-0
	CHEBI ID	135720
	TTD ID	D09WYX
	INTEDE ID	DR0430
	VARIDT ID	DR00146

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM002 Affected cellular transport AM003 Affected organization distribution AM004 Affected intra/extra-hepatic metabolism AM005 Affected excretion pathways AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM003 Complex formation BM010 Transporter inhibition BM014 Interference of cell/tissue uptake BM015 Increase globulin concentration BM017 CYP450 enzyme inhibition BM022 CYP450 enzyme induction BM024 Competitive inhibition of metabolic enzyme BM026 Increased metabolism (Unspecific) BM031 Increased renal excretion (Unspecific) BM043 Additive immunosuppressive effects BM047 Additive thrombogenic effects BM050 Increased risk of bleeding BM054 Increased risk of GI mucosal injury/bleeding risk BM056 Increased risk of hyperammonemia BM057 Increased risk of hyperglycemia BM065 Increased risk of hypokalemia BM067 Increased risk of hyponatremia BM069 Increased risk of lowers seizure threshold BM080 Increased risk of tendinitis/tendon rupture BM081 Increased risk of ventricular arrhythmias BM083 Potentiated the pharmacological effects (Unspecific) BM086 Antagonize the effect of antidiabetic agents BM089 Antagonize the effect of antihypertensive agents BM091 Antagonize the effect of cholinergic agents BM100 Antagonize the effect of vaccine/toxoid BM105 Antagonize the effect of probiotics BM106 Diminish the response to diagnostic skin test antigens BM107 Attenuated pharmacological effects (Unspecific) BM109 Increased risk of other adverse reactions (Unspecific) BM110 Antagonize the effects of immunosuppressants
Relation Graph

Full list of drugs interacting with Deflazacort
Affected gastrointestinal absorption
	Complex formation					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0329		Cholestyramine	C27H47ClN2	137699107	Moderate		Inter Info	[124], [125], [126], [127], [128]
D0381		Colesevelam	C31H67Cl3N4O	160051	Moderate		Inter Info	[124], [125], [126], [127], [128]
D0382		Colestipol	C11H28ClN5O	62816	Moderate		Inter Info	[124], [125], [126], [127], [128]
Affected cellular transport
Affected organization distribution
	Interference of cell/tissue uptake					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0708		Gallium chloride Ga-67	Cl3Ga	73415785	Moderate		Inter Info	[147]
	Increase globulin concentration					Drug Num: 14
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0387		Conjugated estrogens	C18H21NaO5S	45357473	Moderate		Inter Info	[132], [133], [134]
D0388		Conjugated estrogens (topical)	C18H21NaO5S	45357473	Moderate		Inter Info	[132], [133], [134]
D0484		Dienestrol (topical)	C18H18O2	667476	Moderate		Inter Info	[132], [133], [134]
D0487		Diethylstilbestrol	C18H20O2	448537	Moderate		Inter Info	[132], [133], [134]
D0605		Esterified estrogens	NA	NA	Moderate		Inter Info	[132], [133], [134]
D0606		Estradiol	C18H24O2	5757	Moderate		Inter Info	[132], [133], [134]
D0607		Estradiol (topical)	C18H24O2	5757	Moderate		Inter Info	[132], [133], [134]
D0608		Estramustine	C23H31Cl2NO3	259331	Moderate		Inter Info	[132], [133], [134]
D0609		Estrone	C18H22O2	5870	Moderate		Inter Info	[132], [133], [134]
D0610		Estrone sulfate	C18H22O5S	3001028	Moderate		Inter Info	[132], [133], [134]
D0611		Estrone sulfate (topical)	C18H22O5S	3001028	Moderate		Inter Info	[132], [133], [134]
D0619		Ethinylestradiol	C20H24O2	5991	Moderate		Inter Info	[132], [133], [134]
D1011		Mestranol	C21H26O2	6291	Moderate		Inter Info	[132], [133], [134]
D1370		Quinestrol	C25H32O2	9046	Moderate		Inter Info	[132], [133], [134]
Affected intra/extra-hepatic metabolism
	CYP450 enzyme inhibition					Drug Num: 45
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0080		Amprenavir	C25H35N3O6S	65016	Major		Inter Info	[7], [8]
D0116		Atazanavir	C38H52N6O7	148192	Major		Inter Info	[7], [8]
D0302		Ceritinib	C28H36ClN5O3S	57379345	Major		Inter Info	[7], [8]
D0349		Clarithromycin	C38H69NO13	84029	Major		Inter Info	[7], [8]
D0375		Cobicistat	C40H53N7O5S2	25151504	Major		Inter Info	[7], [8]
D0393		Crizotinib	C21H22Cl2FN5O	11626560	Major		Inter Info	[7], [8]
D0413		Dalfopristin	C34H50N4O9S	6323289	Major		Inter Info	[7], [8]
D0426		Darunavir	C27H37N3O7S	213039	Major		Inter Info	[7], [8]
D0171		Berotralstat	C30H26F4N6O	137528262	Major		Inter Info	[7], [8]
D0543		Duvelisib	C22H17ClN6O	50905713	Major		Inter Info	[7], [8]
D0638		Fedratinib	C27H36N6O3S	16722836	Major		Inter Info	[7], [8]
D0696		Fosnetupitant	C31H35F6N4O5P	71544786	Major		Inter Info	[7], [8]
D0906		Letermovir	C29H28F4N4O4	45138674	Major		Inter Info	[7], [8]
D1653		Troleandomycin	C41H67NO15	202225	Major		Inter Info	[7], [8]
D0439		Delavirdine	C22H28N6O3S	5625	Major		Inter Info	[7], [8]
D0497		Diltiazem	C22H26N2O4S	39186	Major		Inter Info	[7], [8]
D0534		Dronedarone	C31H44N2O5S	208898	Major		Inter Info	[7], [8]
D0597		Erythromycin	C37H67NO13	12560	Major		Inter Info	[7], [8]
D0667		Fluconazole	C13H12F2N6O	3365	Major		Inter Info	[7], [8]
D0692		Fosamprenavir	C25H36N3O9PS	131536	Major		Inter Info	[7], [8]
D0693		Fosaprepitant	C23H22F7N4O6P	135413538	Major		Inter Info	[7], [8]
D0789		Idelalisib	C22H18FN7O	11625818	Major		Inter Info	[7], [8]
D0793		Imatinib	C29H31N7O	5291	Major		Inter Info	[7], [8]
D0799		Indinavir	C36H47N5O4	5362440	Major		Inter Info	[7], [8]
D0852		Isavuconazonium	C35H35F2N8O5S+	6918606	Major		Inter Info	[7], [8]
D0867		Itraconazole	C35H38Cl2N8O4	55283	Major		Inter Info	[7], [8]
D0880		Ketoconazole	C26H28Cl2N4O4	456201	Major		Inter Info	[7], [8]
D0946		Lonafarnib	C27H31Br2ClN4O2	148195	Major		Inter Info	[7], [8]
D1117		Nefazodone	C25H32ClN5O2	4449	Major		Inter Info	[7], [8]
D1119		Nelfinavir	C32H45N3O4S	64143	Major		Inter Info	[7], [8]
D1127		Netupitant	C30H32F6N4O	6451149	Major		Inter Info	[7], [8]
D1315		Posaconazole	C37H42F2N8O4	468595	Major		Inter Info	[7], [8]
D1415		Ritonavir	C37H48N6O5S2	392622	Major		Inter Info	[7], [8]
D1444		Saquinavir	C38H50N6O5	441243	Major		Inter Info	[7], [8]
D1541		Telaprevir	C36H53N7O6	3010818	Major		Inter Info	[7], [8]
D1544		Telithromycin	C43H65N5O10	3002190	Major		Inter Info	[7], [8]
D1660		Tucatinib	C26H24N8O2	51039094	Major		Inter Info	[7], [8]
D1706		Voriconazole	C16H14F3N5O	71616	Major		Inter Info	[7], [8]
D0002		Abametapir (topical)	C12H12N2	15664	Moderate		Inter Info	[139]
D0699		Fostamatinib	C23H26FN6O9P	11671467	Moderate		Inter Info	[146]
D0896		Larotrectinib	C21H22F2N6O2	46188928	Moderate		Inter Info	[39], [7], [148]
D0899		Lefamulin	C28H45NO5S	25185057	Moderate		Inter Info	[149]
D1432		Rucaparib	C19H18FN3O	9931954	Moderate		Inter Info	[158]
D1459		Selpercatinib	C29H31N7O3	134436906	Moderate		Inter Info	[7], [159]
D1709		Voxelotor	C19H19N3O3	71602803	Moderate		Inter Info	[164]
	CYP450 enzyme induction					Drug Num: 22
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0194		Bosentan	C27H29N5O6S	104865	Major		Inter Info	[7]
D0255		Carbamazepine	C15H12N2O	2554	Major		Inter Info	[7]
D0300		Cenobamate	C10H10ClN5O2	11962412	Major		Inter Info	[7]
D0406		Dabrafenib	C23H20F3N5O2S2	44462760	Major		Inter Info	[7]
D0953		Lorlatinib	C21H19FN6O2	71731823	Major		Inter Info	[7]
D1258		Pexidartinib	C20H15ClF3N5	25151352	Major		Inter Info	[7]
D0554		Efavirenz	C14H9ClF3NO2	64139	Major		Inter Info	[7]
D0578		Enzalutamide	C21H16F4N4O2S	15951529	Major		Inter Info	[7]
D0628		Etravirine	C20H15BrN6O	193962	Major		Inter Info	[7]
D0697		Fosphenytoin	C16H15N2O6P	56339	Major		Inter Info	[7]
D0958		Lumacaftor	C24H18F2N2O5	16678941	Major		Inter Info	[7], [55]
D1078		Mitotane	C14H10Cl4	4211	Major		Inter Info	[7]
D1081		Modafinil	C15H15NO2S	4236	Major		Inter Info	[7]
D1099		Nafcillin	C21H22N2O5S	8982	Major		Inter Info	[7]
D1128		Nevirapine	C15H14N4O	4463	Major		Inter Info	[7]
D1265		Phenobarbital	C12H12N2O3	4763	Major		Inter Info	[7]
D1283		Phenytoin	C15H12N2O2	1775	Major		Inter Info	[7]
D1340		Primidone	C12H14N2O2	4909	Major		Inter Info	[7]
D1399		Rifabutin	C46H62N4O11	135398743	Major		Inter Info	[7]
D1400		Rifampicin	C43H58N4O12	135398735	Major		Inter Info	[7], [55]
D1502		St. John's Wort	NA	NA	Major		Inter Info	[7]
D1538		Tazemetostat	C34H44N4O4	66558664	Moderate		Inter Info	[163]
	Competitive inhibition of metabolic enzyme					Drug Num: 4
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0402		Cyclosporine	C62H111N11O12	5284373	Moderate		Inter Info	[135], [136], [137], [138]
D1476		Sirolimus	C51H79NO13	5284616	Moderate		Inter Info	[181], [182]
D1526		Tacrolimus	C44H69NO12	445643	Moderate		Inter Info	[181], [182]
D1549		Temsirolimus	C56H87NO16	6918289	Moderate		Inter Info	[181], [182]
	Increased metabolism (Unspecific)					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1493		Somapacitan	C54H95N13O20S2	129894493	Moderate		Inter Info	[160], [161], [162]
D1494		Somatotropin	NA	NA	Moderate		Inter Info	[160], [161], [162]
D1495		Somatrem	C43H72N14O14	5487805	Moderate		Inter Info	[160], [161], [162]
Affected excretion pathways
	Increased renal excretion (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0858		Isoniazid	C6H7N3O	3767	Minor		Inter Info	[187], [188], [189]
Pharmacodynamic additive effects
	Additive immunosuppressive effects					Drug Num: 35
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0023		Adalimumab	NA	NA	Major		Inter Info	[1], [2], [3], [4], [5], [6]
D0146		Baricitinib	C16H17N7O2S	44205240	Major		Inter Info	[9], [10], [11]
D0304		Certolizumab pegol	NA	NA	Major		Inter Info	[1], [5], [6]
D0348		Cladribine	C10H12ClN5O3	20279	Major		Inter Info	[7], [34]
D0203		Brexucabtagene autoleucel	NA	NA	Major		Inter Info	[7]
D1474		Siponimod	C29H35F3N2O3	44599207	Major		Inter Info	[39], [40]
D1666		Upadacitinib	C17H19F3N6O	58557659	Major		Inter Info	[48]
D0501		Dinutuximab	NA	NA	Major		Inter Info	[7]
D0614		Etanercept	NA	NA	Major		Inter Info	[1], [2], [3], [4], [5], [6]
D0661		Fingolimod	C19H33NO2	107970	Major		Inter Info	[54]
D0736		Golimumab	NA	NA	Major		Inter Info	[1], [2], [3], [4], [5], [6]
D0802		Infliximab	NA	NA	Major		Inter Info	[1], [2], [3], [4], [5], [6]
D1111		Natalizumab	NA	NA	Major		Inter Info	[56]
D1556		Teriflunomide	C12H9F3N2O2	54684141	Major		Inter Info	[57], [58]
D1600		Tofacitinib	C16H20N6O	9926791	Major		Inter Info	[9], [10], [11]
D0032		Alefacept	NA	NA	Moderate		Inter Info	[41], [88], [89]
D0033		Alemtuzumab	NA	NA	Moderate		Inter Info	[90]
D0085		Anakinra	C20H23N5O7S2	146171046	Moderate		Inter Info	[96], [97], [98]
D0118		Atezolizumab	NA	NA	Moderate		Inter Info	[104], [105], [106], [39], [107], [7], [108], [109], [110], [111]
D0246		Canakinumab	NA	NA	Moderate		Inter Info	[96], [97], [98]
D0299		Cemiplimab	NA	NA	Moderate		Inter Info	[104], [105], [106], [39], [107], [7], [108], [109], [110], [111]
D0507		Diroximel fumarate	C11H13NO6	73330464	Moderate		Inter Info	[145]
D1085		Monomethyl fumarate	C5H6O4	5369209	Moderate		Inter Info	[145]
D1162		Ocrelizumab	NA	NA	Moderate		Inter Info	[150]
D0443		Denosumab	NA	NA	Moderate		Inter Info	[165]
D0499		Dimethyl fumarate	C6H8O4	637568	Moderate		Inter Info	[145]
D0541		Durvalumab	NA	NA	Moderate		Inter Info	[104], [105], [106], [39], [107], [7], [108], [109], [110], [111]
D0553		Efalizumab	NA	NA	Moderate		Inter Info	[166]
D0841		Ipilimumab	NA	NA	Moderate		Inter Info	[104], [105], [106], [39], [107], [7], [108], [109], [110], [111]
D1150		Nivolumab	NA	NA	Moderate		Inter Info	[104], [105], [106], [39], [107], [7], [108], [109], [110], [111]
D1174		Omacetaxine mepesuccinate	C29H39NO9	285033	Moderate		Inter Info	[178]
D1240		Pembrolizumab	NA	NA	Moderate		Inter Info	[104], [105], [106], [39], [107], [7], [108], [109], [110], [111]
D1403		Rilonacept	NA	NA	Moderate		Inter Info	[96], [97], [98]
D1422		Roflumilast	C17H14Cl2F2N2O3	449193	Moderate		Inter Info	[7], [179]
D1671		Ustekinumab	NA	NA	Moderate		Inter Info	[183]
	Additive thrombogenic effects					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1569		Thalidomide	C13H10N2O4	5426	Major		Inter Info	[59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74]
	Increased risk of bleeding					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0432		Deferasirox	C21H15N3O4	214348	Major		Inter Info	[35], [36]
D0447		Desirudin	C287H440N80O110S6	16129703	Major		Inter Info	[49]
	Increased risk of GI mucosal injury/bleeding risk					Drug Num: 28
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0017		Acetylsalicylic acid	C9H8O4	2244	Moderate		Inter Info	[85], [86], [87]
D0210		Bromfenac	C15H12BrNO3	60726	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D0298		Celecoxib	C17H14F3N3O2S	2662	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D0331		Choline salicylate	C12H19NO4	54686350	Moderate		Inter Info	[143], [144], [85], [86], [87]
D0476		Diclofenac	C14H11Cl2NO2	3033	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D0489		Diflunisal	C13H8F2O3	3059	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D0624		Etodolac	C17H21NO3	3308	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D0645		Fenoprofen	C15H14O3	3342	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D0680		Flurbiprofen	C15H13FO2	3394	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D0786		Ibuprofen	C13H18O2	3672	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D0800		Indomethacin	C19H16ClNO4	3715	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D0881		Ketoprofen	C16H14O3	3825	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D0882		Ketorolac	C15H13NO3	3826	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D0988		Meclofenamic acid	C14H11Cl2NO2	4037	Moderate		Inter Info	[119], [122], [123]
D0991		Mefenamic acid	C15H15NO2	4044	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D0995		Meloxicam	C14H13N3O4S2	54677470	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D1097		Nabumetone	C15H16O2	4409	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D1109		Naproxen	C14H14O3	156391	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D1196		Oxaprozin	C18H15NO3	4614	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D1272		Phenyl salicylate	C13H10O3	8361	Moderate		Inter Info	[85], [86], [87]
D1274		Phenylbutazone	C19H20N2O2	4781	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D1302		Pitolisant	C17H26ClNO	9948102	Moderate		Inter Info	[7]
D1421		Rofecoxib	C17H14O4S	5090	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D1439		Salicylic acid (sodium)	C7H6O3	338	Moderate		Inter Info	[85], [86], [87]
D1442		Salsalate	C14H10O5	5161	Moderate		Inter Info	[143], [144], [85], [86], [87]
D1520		Sulindac	C20H17FO3S	1548887	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D1606		Tolmetin	C15H15NO3	5509	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
D1674		Valdecoxib	C16H14N2O3S	119607	Moderate		Inter Info	[115], [116], [117], [118], [119], [87], [120], [121], [122], [83], [123]
	Increased risk of hyperammonemia					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0732		Glycerol phenylbutyrate	C33H38O6	10482134	Moderate		Inter Info	[39], [169], [170]
D1275		Phenylbutyric acid	C10H12O2	4775	Moderate		Inter Info	[39], [169], [170]
	Increased risk of hyperglycemia					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0113		Asparaginase Erwinia chrysanthemi	NA	NA	Moderate		Inter Info	[101], [102], [103]
D0114		Asparaginase Escherichia coli	NA	NA	Moderate		Inter Info	[101], [102], [103]
D1234		Pegaspargase	C14H19NO	436058	Moderate		Inter Info	[101], [102], [103]
	Increased risk of hypokalemia					Drug Num: 39
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0012		Acetazolamide	C4H6N4O3S2	1986	Moderate		Inter Info	[82], [83], [84]
D0075		Amphotericin B	C47H73NO17	5280965	Moderate		Inter Info	[82], [83], [84]
D0076		Amphotericin B (cholesteryl sulfate)	C47H73NO17	5280965	Moderate		Inter Info	[82], [83], [84]
D0077		Amphotericin B (lipid complex)	C47H73NO17	5280965	Moderate		Inter Info	[82], [83], [84]
D0078		Amphotericin B (liposomal)	C47H73NO17	5280965	Moderate		Inter Info	[82], [83], [84]
D0158		Bendroflumethiazide	C15H14F3N3O4S2	2315	Moderate		Inter Info	[82], [83], [84]
D0166		Benzthiazide	C15H14ClN3O4S3	2343	Moderate		Inter Info	[82], [83], [84]
D0184		Bisacodyl	C22H19NO4	2391	Moderate		Inter Info	[112], [113], [114]
D0217		Bumetanide	C17H20N2O5S	2471	Moderate		Inter Info	[82], [83], [84]
D0252		Capreomycin	C50H88N28O15	3000502	Moderate		Inter Info	[82], [83], [84]
D0269		Castor oil	C57H104O9	14030006	Moderate		Inter Info	[112], [113], [114]
D0321		Chlorothiazide	C7H6ClN3O4S2	2720	Moderate		Inter Info	[82], [83], [84]
D0326		Chlorthalidone	C14H11ClN2O4S	2732	Moderate		Inter Info	[82], [83], [84]
D0344		Cisplatin	Cl2H6N2Pt	5702198	Moderate		Inter Info	[82], [83], [84]
D0701		Frangula purshiana bark	NA	NA	Moderate		Inter Info	[112], [113], [114]
D0887		Lactitol	C12H24O11	157355	Moderate		Inter Info	[112], [113], [114]
D0479		Diclofenamide	C6H6Cl2N2O4S2	3038	Moderate		Inter Info	[82], [83], [84]
D0613		Etacrynic acid	C13H12Cl2O4	3278	Moderate		Inter Info	[82], [83], [84]
D0694		Foscarnet	CH3O5P	3415	Moderate		Inter Info	[82], [83], [84]
D0704		Furosemide	C12H11ClN2O5S	3440	Moderate		Inter Info	[82], [83], [84]
D0731		Glycerin	C3H8O3	753	Moderate		Inter Info	[112], [113], [114]
D0771		Hydrochlorothiazide	C7H8ClN3O4S2	3639	Moderate		Inter Info	[82], [83], [84]
D0775		Hydroflumethiazide	C8H8F3N3O4S2	3647	Moderate		Inter Info	[82], [83], [84]
D0798		Indapamide	C16H16ClN3O3S	3702	Moderate		Inter Info	[82], [83], [84]
D0888		Lactulose	C12H22O11	11333	Moderate		Inter Info	[112], [113], [114]
D0970		Magnesium citrate	C12H10Mg3O14	6099959	Moderate		Inter Info	[112], [113], [114]
D0973		Magnesium hydroxide	H2MgO2	14791	Moderate		Inter Info	[112], [113], [114]
D0975		Magnesium sulfate	MgO4S	24083	Moderate		Inter Info	[112], [113], [114]
D1018		Methazolamide	C5H8N4O3S2	4100	Moderate		Inter Info	[82], [83], [84]
D1048		Metolazone	C16H16ClN3O3S	4170	Moderate		Inter Info	[82], [83], [84]
D1069		Mineral oil	NA	NA	Moderate		Inter Info	[112], [113], [114]
D1231		Patiromer	NA	NA	Moderate		Inter Info	[82], [83], [84]
D1266		Phenolphthalein	C20H14O4	4764	Moderate		Inter Info	[112], [113], [114]
D1287		Picosulfuric acid	C18H15NO8S2	5243	Moderate		Inter Info	[112], [113], [114]
D1309		Polyethylene glycol (3350)	C2H6O2	174	Moderate		Inter Info	[112], [113], [114]
D1311		Polythiazide	C11H13ClF3N3O4S3	4870	Moderate		Inter Info	[82], [83], [84]
D1605		Tolevamer	C11H16O3S	58817179	Moderate		Inter Info	[82], [83], [84]
D1611		Torasemide	C16H20N4O3S	41781	Moderate		Inter Info	[82], [83], [84]
D1633		Trichlormethiazide	C8H8Cl3N3O4S2	5560	Moderate		Inter Info	[82], [83], [84]
	Increased risk of hyponatremia					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0449		Desmopressin	C46H64N14O12S2	5311065	Major		Inter Info	[50], [7], [51], [52], [53], [39]
	Increased risk of lowers seizure threshold					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0220		Bupropion	C13H18ClNO	444	Major		Inter Info	[12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26]
D0054		Amifampridine	C5H7N3	5918	Moderate		Inter Info	[94], [95]
	Increased risk of tendinitis/tendon rupture					Drug Num: 13
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0340		Cinoxacin	C12H10N2O5	2762	Major		Inter Info	[27], [28], [29], [30], [31], [32], [33]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Major		Inter Info	[27], [28], [29], [30], [31], [32], [33]
D0155		Bempedoic acid	C19H36O5	10472693	Major		Inter Info	[37], [38]
D0438		Delafloxacin	C18H12ClF3N4O4	487101	Major		Inter Info	[27], [28], [29], [30], [31], [32], [33]
D0573		Enoxacin	C15H17FN4O3	3229	Major		Inter Info	[27], [28], [29], [30], [31], [32], [33]
D0712		Gatifloxacin	C19H22FN3O4	5379	Major		Inter Info	[27], [28], [29], [30], [31], [32], [33]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Major		Inter Info	[27], [28], [29], [30], [31], [32], [33]
D0919		Levofloxacin	C18H20FN3O4	149096	Major		Inter Info	[27], [28], [29], [30], [31], [32], [33]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Major		Inter Info	[27], [28], [29], [30], [31], [32], [33]
D1092		Moxifloxacin	C21H24FN3O4	152946	Major		Inter Info	[27], [28], [29], [30], [31], [32], [33]
D1102		Nalidixic acid	C12H12N2O3	4421	Major		Inter Info	[27], [28], [29], [30], [31], [32], [33]
D1155		Norfloxacin	C16H18FN3O3	4539	Major		Inter Info	[27], [28], [29], [30], [31], [32], [33]
D1165		Ofloxacin	C18H20FN3O4	4583	Major		Inter Info	[27], [28], [29], [30], [31], [32], [33]
	Increased risk of ventricular arrhythmias					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0067		Amisulpride	C17H27N3O4S	2159	Moderate		Inter Info	[39], [7]
	Potentiated the pharmacological effects (Unspecific)					Drug Num: 7
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0677		Fluoxymesterone	C20H29FO3	6446	Moderate		Inter Info	[167], [168]
D1042		Methyltestosterone	C20H30O2	6010	Moderate		Inter Info	[167], [168]
D1195		Oxandrolone	C19H30O3	5878	Moderate		Inter Info	[167], [168]
D1207		Oxymetholone	C21H32O3	5281034	Moderate		Inter Info	[167], [168]
D1503		Stanozolol	C21H32N2O	25249	Moderate		Inter Info	[167], [168]
D1558		Testosterone	C19H28O2	6013	Moderate		Inter Info	[167], [168]
D1559		Testosterone (topical)	C19H28O2	6013	Moderate		Inter Info	[167], [168]
	Increased risk of other adverse reactions (Unspecific)					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1694		Vigabatrin	C6H11NO2	5665	Major		Inter Info	[75], [76], [77]
D0863		Isotretinoin	C20H28O2	5282379	Moderate		Inter Info	[174], [175], [176]
D1426		Romosozumab	NA	NA	Moderate		Inter Info	[180]
Pharmacodynamic antagonistic effects
	Antagonize the effect of antidiabetic agents					Drug Num: 38
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0009		Acarbose	C25H43NO18	41774	Moderate		Inter Info	[78], [79], [80]
D0029		Albiglutide	C148H224N40O45	145994868	Moderate		Inter Info	[78], [79], [80]
D0042		Alogliptin	C18H21N5O2	11450633	Moderate		Inter Info	[78], [79], [80]
D0245		Canagliflozin	C24H25FO5S	24812758	Moderate		Inter Info	[78], [79], [80]
D0418		Dapagliflozin	C21H25ClO6	9887712	Moderate		Inter Info	[78], [79], [80]
D1779		Dulaglutide	NA	NA	Moderate		Inter Info	[78], [79], [80]
D0565		Empagliflozin	C23H27ClO7	11949646	Moderate		Inter Info	[78], [79], [80]
D1782		Ertugliflozin	C22H25ClO7	44814423	Moderate		Inter Info	[78], [79], [80]
D1784		Exenatide	C184H282N50O60S	45588096	Moderate		Inter Info	[78], [79], [80]
D0727		Glimepiride	C24H34N4O5S	3476	Moderate		Inter Info	[78], [79], [80]
D0728		Glipizide	C21H27N5O4S	3478	Moderate		Inter Info	[78], [79], [80]
D0730		Glyburide	C23H28ClN3O5S	3488	Moderate		Inter Info	[78], [79], [80]
D0807		Insulin aspart (aspart protamine)	C256H381N65O79S6	118984445	Moderate		Inter Info	[78], [79], [80]
D0808		Insulin aspart (aspart)	C256H381N65O79S6	118984445	Moderate		Inter Info	[78], [79], [80]
D0809		Insulin degludec	C274H411N65O81S6	118984462	Moderate		Inter Info	[78], [79], [80]
D0810		Insulin detemir	C267H402N64O76S6	16137271	Moderate		Inter Info	[78], [79], [80]
D0811		Insulin glargine	C267H404N72O78S6	118984454	Moderate		Inter Info	[78], [79], [80]
D0813		Insulin human	C257H383N65O77S6	118984375	Moderate		Inter Info	[78], [79], [80]
D0814		Insulin human (inhalation, rapid acting)	C257H383N65O77S6	118984375	Moderate		Inter Info	[78], [79], [80]
D0815		Insulin human (isophane)	C257H383N65O77S6	118984375	Moderate		Inter Info	[78], [79], [80]
D0816		Insulin human (regular)	C257H383N65O77S6	118984375	Moderate		Inter Info	[78], [79], [80]
D0817		Insulin human (zinc extended)	C257H383N65O77S6	118984375	Moderate		Inter Info	[78], [79], [80]
D0818		Insulin human (zinc)	C257H383N65O77S6	118984375	Moderate		Inter Info	[78], [79], [80]
D0819		Insulin lispro	C257H389N65O77S6	16132438	Moderate		Inter Info	[78], [79], [80]
D0820		Insulin lispro (protamine)	C257H389N65O77S6	16132438	Moderate		Inter Info	[78], [79], [80]
D0930		Linagliptin	C25H28N8O2	10096344	Moderate		Inter Info	[78], [79], [80]
D0941		Lixisenatide	C215H347N61O65S	90472060	Moderate		Inter Info	[78], [79], [80]
D1015		Metformin	C4H11N5	4091	Moderate		Inter Info	[78], [79], [80]
D1064		Miglitol	C8H17NO5	441314	Moderate		Inter Info	[78], [79], [80]
D1112		Nateglinide	C19H27NO3	5311309	Moderate		Inter Info	[78], [79], [80]
D1294		Pioglitazone	C19H20N2O3S	4829	Moderate		Inter Info	[78], [79], [80]
D1326		Pramlintide	C171H267N51O53S2	70691388	Moderate		Inter Info	[78], [79], [80]
D1392		Repaglinide	C27H36N2O4	65981	Moderate		Inter Info	[78], [79], [80]
D1449		Saxagliptin	C18H25N3O2	11243969	Moderate		Inter Info	[78], [79], [80]
D1477		Sitagliptin	C16H15F6N5O	4369359	Moderate		Inter Info	[78], [79], [80]
D1601		Tolazamide	C14H21N3O3S	5503	Moderate		Inter Info	[78], [79], [80]
D1603		Tolbutamide	C12H18N2O3S	5505	Moderate		Inter Info	[78], [79], [80]
D1652		Troglitazone	C24H27NO5S	5591	Moderate		Inter Info	[78], [79], [80]
	Antagonize the effect of antihypertensive agents					Drug Num: 57
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0010		Acebutolol	C18H28N2O4	1978	Moderate		Inter Info	[7], [81]
D0038		Aliskiren	C30H53N3O6	5493444	Moderate		Inter Info	[7], [81]
D0058		Amiloride	C6H8ClN7O	16231	Moderate		Inter Info	[7], [81]
D0069		Amlodipine	C20H25ClN2O5	2162	Moderate		Inter Info	[7], [81]
D0117		Atenolol	C14H22N2O3	2249	Moderate		Inter Info	[7], [81]
D0138		Azilsartan medoxomil	C30H24N4O8	135409642	Moderate		Inter Info	[7], [81]
D0156		Benazepril	C24H28N2O5	5362124	Moderate		Inter Info	[7], [81]
D0173		Betaxolol	C18H29NO3	2369	Moderate		Inter Info	[7], [81]
D0188		Bisoprolol	C18H31NO4	2405	Moderate		Inter Info	[7], [81]
D0254		Captopril	C9H15NO3S	44093	Moderate		Inter Info	[7], [81]
D0267		Carvedilol	C24H26N2O4	2585	Moderate		Inter Info	[7], [81]
D0352		Clevidipine	C21H23Cl2NO6	153994	Moderate		Inter Info	[7], [81]
D0363		Clonidine	C9H9Cl2N3	2803	Moderate		Inter Info	[7], [81]
D1887		Semaglutide	C187H291N45O59	56843331	Moderate		Inter Info	[78], [79], [80]
D0444		Deserpidine	C32H38N2O8	8550	Moderate		Inter Info	[7], [81]
D0474		Diazoxide	C8H7ClN2O2S	3019	Moderate		Inter Info	[7], [81]
D0524		Doxazosin	C23H25N5O5	3157	Moderate		Inter Info	[7], [81]
D0567		Enalapril	C20H28N2O5	5388962	Moderate		Inter Info	[7], [81]
D0585		Eplerenone	C24H30O6	443872	Moderate		Inter Info	[7], [81]
D0587		Eprosartan	C23H24N2O4S	5281037	Moderate		Inter Info	[7], [81]
D0640		Felodipine	C18H19Cl2NO4	3333	Moderate		Inter Info	[7], [81]
D0644		Fenoldopam	C16H16ClNO3	3341	Moderate		Inter Info	[7], [81]
D0695		Fosinopril	C30H46NO7P	55891	Moderate		Inter Info	[7], [81]
D0742		Guanabenz	C8H8Cl2N4	5702063	Moderate		Inter Info	[7], [81]
D0743		Guanadrel	C10H19N3O2	38521	Moderate		Inter Info	[7], [81]
D0744		Guanethidine	C10H22N4	3518	Moderate		Inter Info	[7], [81]
D0745		Guanfacine	C9H9Cl2N3O	3519	Moderate		Inter Info	[7], [81]
D0770		Hydralazine	C8H8N4	3637	Moderate		Inter Info	[7], [81]
D0844		Irbesartan	C25H28N6O	3749	Moderate		Inter Info	[7], [81]
D0865		Isradipine	C19H21N3O5	3784	Moderate		Inter Info	[7], [81]
D0911		Levamlodipine	C20H25ClN2O5	9822750	Moderate		Inter Info	[7], [81]
D0938		Lisinopril	C21H31N3O5	5362119	Moderate		Inter Info	[7], [81]
D0954		Losartan	C22H23ClN6O	3961	Moderate		Inter Info	[7], [81]
D1035		Methyldopa	C10H13NO4	38853	Moderate		Inter Info	[7], [81]
D1049		Metoprolol	C15H25NO3	4171	Moderate		Inter Info	[7], [81]
D1072		Minoxidil	C9H15N5O	4201	Moderate		Inter Info	[7], [81]
D1082		Moexipril	C27H34N2O7	91270	Moderate		Inter Info	[7], [81]
D1098		Nadolol	C17H27NO4	39147	Moderate		Inter Info	[7], [81]
D1114		Nebivolol	C22H25F2NO4	71301	Moderate		Inter Info	[7], [81]
D1130		Nicardipine	C26H29N3O6	4474	Moderate		Inter Info	[7], [81]
D1134		Nifedipine	C17H18N2O6	4485	Moderate		Inter Info	[7], [81]
D1141		Nisoldipine	C20H24N2O6	4499	Moderate		Inter Info	[7], [81]
D1147		Nitroprusside	C5FeN6O	11953891	Moderate		Inter Info	[7], [81]
D1244		Penbutolol	C18H29NO2	37464	Moderate		Inter Info	[7], [81]
D1256		Perindopril	C19H32N2O5	107807	Moderate		Inter Info	[7], [81]
D1293		Pindolol	C14H20N2O2	4828	Moderate		Inter Info	[7], [81]
D1331		Prazosin	C19H21N5O4	4893	Moderate		Inter Info	[7], [81]
D1369		Quinapril	C25H30N2O5	54892	Moderate		Inter Info	[7], [81]
D1379		Ramipril	C23H32N2O5	5362129	Moderate		Inter Info	[7], [81]
D1393		Reserpine	C33H40N2O9	5770	Moderate		Inter Info	[7], [81]
D1545		Telmisartan	C33H30N4O2	65999	Moderate		Inter Info	[7], [81]
D1552		Terazosin	C19H25N5O4	5401	Moderate		Inter Info	[7], [81]
D1585		Timolol	C13H24N4O3S	33624	Moderate		Inter Info	[7], [81]
D1618		Trandolapril	C24H34N2O5	5484727	Moderate		Inter Info	[7], [81]
D1631		Triamterene	C12H11N7	5546	Moderate		Inter Info	[7], [81]
D1643		Trimethaphan	C22H25N2OS+	23576	Moderate		Inter Info	[7], [81]
D1679		Valsartan	C24H29N5O3	60846	Moderate		Inter Info	[7], [81]
	Antagonize the effect of cholinergic agents					Drug Num: 4
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0052		Ambenonium	C28H42Cl2N4O2+2	2131	Moderate		Inter Info	[91], [92], [93]
D0552		Edrophonium	C10H16NO+	3202	Moderate		Inter Info	[91], [92], [93]
D1122		Neostigmine	C12H19N2O2+	4456	Moderate		Inter Info	[91], [92], [93]
D1365		Pyridostigmine	C9H13N2O2+	4991	Moderate		Inter Info	[91], [92], [93]
	Antagonize the effect of vaccine/toxoid					Drug Num: 21
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1890		Smallpox (Vaccinia) Vaccine, Live	NA	NA	Major		Inter Info	[41], [42], [43]
D1897		Talimogene laherparepvec	NA	NA	Major		Inter Info	[44]
D1914		Typhoid vaccine (live)	NA	NA	Major		Inter Info	[45], [46], [47]
D1920		Varicella Zoster Vaccine (Recombinant)	NA	NA	Major		Inter Info	[45], [46], [47]
D1839		Measles virus vaccine live attenuated	NA	NA	Major		Inter Info	[45], [46], [47]
D1849		Mumps virus strain B level jeryl lynn live antigen	NA	NA	Major		Inter Info	[45], [46], [47]
D1881		Rotavirus vaccine	NA	NA	Major		Inter Info	[45], [46], [47]
D1882		Rubella virus vaccine	NA	NA	Major		Inter Info	[45], [46], [47]
D1922		Yellow Fever Vaccine	NA	NA	Major		Inter Info	[45], [46], [47]
D0089		Anthrax vaccine	NA	NA	Moderate		Inter Info	[41], [99], [100]
D0366		Clostridium tetani toxoid antigen (formaldehyde inactivated)	NA	NA	Moderate		Inter Info	[41], [99], [100]
D0803		Influenza A virus A/California/7/2009 (H1N1)-like antigen (propiolactone inactivated)	NA	NA	Moderate		Inter Info	[41], [99], [100]
D0804		Influenza A virus A/Vietnam/1194/2004 (H5N1) antigen (formaldehyde inactivated)	NA	NA	Moderate		Inter Info	[41], [99], [100]
D0999		Meningococcal polysaccharide vaccine group C	NA	NA	Moderate		Inter Info	[41], [99], [100]
D1259		Pfizer-BioNTech Covid-19 Vaccine	NA	NA	Moderate		Inter Info	[151], [41], [39], [152], [153], [154], [99], [155], [156], [157], [100]
D1662		Typhoid vaccine (inactivated)	NA	NA	Moderate		Inter Info	[41], [99], [100]
D1692		Vibrio cholerae CVD 103-HgR strain live antigen	NA	NA	Moderate		Inter Info	[41], [99], [100]
D0755		Hepatitis A Vaccine	NA	NA	Moderate		Inter Info	[41], [99], [100]
D0756		Hepatitis B Vaccine (Recombinant)	NA	NA	Moderate		Inter Info	[41], [99], [100]
D0767		Human papillomavirus type 11 L1 capsid protein antigen	NA	NA	Moderate		Inter Info	[41], [99], [100]
D1838		Lyme disease vaccine (recombinant OspA)	NA	NA	Moderate		Inter Info	[177]
	Antagonize the effect of probiotics					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1749		Bifidobacterium longum infantis	NA	NA	Moderate		Inter Info	[140], [141], [142]
D1827		Lactobacillus acidophilus	NA	NA	Moderate		Inter Info	[140], [141], [142]
	Diminish the response to diagnostic skin test antigens					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1765		Coccidioides immitis spherule	NA	NA	Moderate		Inter Info	[129], [130], [131]
D1912		Trichophyton mentagrophytes	NA	NA	Moderate		Inter Info	[129], [130], [131]
D1913		Tuberculin purified protein derivative	NA	NA	Moderate		Inter Info	[129], [130], [131]
	Attenuated pharmacological effects (Unspecific)					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1817		Indium In-111 oxyquinoline	C27H18InN3O3	16685037	Moderate		Inter Info	[171]
D1822		Iodide I-123	I-	135300	Moderate		Inter Info	[172], [76], [173]
	Antagonize the effects of immunosuppressants					Drug Num: 5
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0545		Echinacea	NA	NA	Minor		Inter Info	[184], [185], [186]
D1722		Zinc acetate	C4H6O4Zn	11192	Minor		Inter Info	[184], [185], [186]
D1703		Vitamin E	C29H50O2	14985	Minor		Inter Info	[184], [185], [186]
D1724		Zinc gluconate	C12H22O14Zn	443445	Minor		Inter Info	[184], [185], [186]
D1725		Zinc sulfate	O4SZn	24424	Minor		Inter Info	[184], [185], [186]

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146	Product Information. Tavalisse (fostamatinib). Rigel Pharmaceuticals, South San Francisco, CA.
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152	Product Information. Biothrax (anthrax vaccine adsorbed). Emergent BioSolutions Inc., Lansing, MI.
153	Product Information. Fluzone Influenza Vaccine (influenza virus vaccine). Connaught, Swiftwater, PA.
154	Product Information. Havrix (hepatitis A vaccine). SmithKline Beecham, Philadelphia, PA.
155	Product Information. Influenza Virus Vaccine, H5N1, Inactivated (influenza virus vaccine, H5N1, inactivated). GlaxoSmithKline, Research Triangle Park, NC.
156	Product Information. Omnihib (haemophilus b conjugate vaccine). SmithKline Beecham, Philadelphia, PA.
157	CDC Centers for Disease Control and Prevention "Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Approved or Authorized in the United States.".
158	EMA. European Medicines Agency. European Union "EMA - List of medicines under additional monitoring.".
159	Product Information. Retevmo (selpercatinib). Lilly, Eli and Company, Indianapolis, IN.
160	Product Information. Norditropin Cartridge (somatropin). Novo Nordisk Pharmaceuticals Inc, Princeton, NJ.
161	Product Information. Nutropin (somatropin). Genentech, South San Francisco, CA.
162	Product Information. Protropin (somatrem). Genentech, South San Francisco, CA.
163	Product Information. Tazverik (tazemetostat). Epizyme, Inc, Cambridge, MA.
164	Product Information. Oxbryta (voxelotor). Global Blood Therapeutics, Inc., South San Francisco, CA.
165	Product Information. Prolia (denosumab). Amgen USA, Thousand Oaks, CA.
166	Product Information. Raptiva (efalizumab). Genentech, South San Francisco, CA.
167	Product Information. AndroGel (testosterone). Unimed Pharmaceuticals, Buffalo Grove, IL.
168	Product Information. Oxandrin (oxandrolone). Bio-Tech, Levittown, PA.
169	Product Information. Buphenyl (sodium phenylbutyrate). Horizon Pharma USA Inc, Northbrook, IL.
170	Product Information. Ravicti (glycerol phenylbutyrate). Hyperion Therapeutics Inc, South San Francisco, CA.
171	Product Information. Indium Oxyquinoline In-111 (indium oxyquinoline In-111). GE Healthcare, Princeton, NJ.
172	Product Information. Rexulti (brexpiprazole). Otsuka American Pharmaceuticals Inc, Rockville, MD.
173	Product Information. Sodium Iodide I-123 (sodium iodide I-123). GE Healthcare, Princeton, NJ.
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179	Product Information. Daxas (roflumilast). Nycomed Inc, Princeton, NJ.
180	Product Information. Evenity (romosozumab). Amgen USA, Thousand Oaks, CA.
181	Product Information. Prograf (tacrolimus). Fujisawa, Deerfield, IL.
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