Drug General Information (ID: D0128)
  Drug Name
Avanafil
  Drug Type Small molecule
  Drug Synonymous
Stendra (TN)
    Click to Show/Hide
  Disease Class HA00-HA01: Sexual dysfunction
  Therapeutic Class Impotence Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C23H26ClN7O3
  InChI 1S/C23H26ClN7O3/c1-34-19-6-5-15(10-18(19)24)11-27-21-17(22(33)28-13-20-25-7-3-8-26-20)12-29-23(30-21)31-9-2-4-16(31)14-32/h3,5-8,10,12,16,32H,2,4,9,11,13-14H2,1H3,(H,28,33)(H,27,29,30)/t16-/m0/s1
  InChIKey WEAJZXNPAWBCOA-INIZCTEOSA-N
  Canonical SMILES COC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCCC4CO)Cl
  External Link
Pubchem ID 9869929
CAS Number 330784-47-9
CHEBI ID 66876
TTD ID D0Y5JC
INTEDE ID DR0159

Drug-Drug Interaction Network
  Sunburst Graph
AM004  Affected intra/extra-hepatic metabolism
AM006  Pharmacodynamic additive effects
BM017  CYP450 enzyme inhibition
BM022  CYP450 enzyme induction
BM042  Additive hypotensive effects
BM109  Increased risk of other adverse reactions (Unspecific)
  Relation Graph
 Full list of drugs interacting with Avanafil
      Affected intra/extra-hepatic metabolism
   CYP450 enzyme inhibition Drug Num:  53
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0080
 
Amprenavir
 
C25H35N3O6S
 
65016 
Major    Inter Info   
[1]
D0100
 
Aprepitant
 
C23H21F7N4O3
 
135413536 
Major    Inter Info   
[1]
D0116
 
Atazanavir
 
C38H52N6O7
 
148192 
Major    Inter Info   
[5], [6], [1]
D0171
 
Berotralstat
 
C30H26F4N6O
 
137528262 
Major    Inter Info   
[1]
D0192
 
Boceprevir
 
C27H45N5O5
 
10324367 
Major    Inter Info   
[5], [6], [1]
D0302
 
Ceritinib
 
C28H36ClN5O3S
 
57379345 
Major    Inter Info   
[5], [6], [1]
D0375
 
Cobicistat
 
C40H53N7O5S2
 
25151504 
Major    Inter Info   
[5], [6], [1]
D0393
 
Crizotinib
 
C21H22Cl2FN5O
 
11626560 
Major    Inter Info   
[1]
D0543
 
Duvelisib
 
C22H17ClN6O
 
50905713 
Major    Inter Info   
[1]
D0638
 
Fedratinib
 
C27H36N6O3S
 
16722836 
Major    Inter Info   
[1]
D0693
 
Fosaprepitant
 
C23H22F7N4O6P
 
135413538 
Major    Inter Info   
[1]
D0696
 
Fosnetupitant
 
C31H35F6N4O5P
 
71544786 
Major    Inter Info   
[2], [1]
D0789
 
Idelalisib
 
C22H18FN7O
 
11625818 
Major    Inter Info   
[5], [6], [1]
D0852
 
Isavuconazonium
 
C35H35F2N8O5S+
 
6918606 
Major    Inter Info   
[1]
D0906
 
Letermovir
 
C29H28F4N4O4
 
45138674 
Major    Inter Info   
[1]
D0946
 
Lonafarnib
 
C27H31Br2ClN4O2
 
148195 
Major    Inter Info   
[5], [6], [1]
D1127
 
Netupitant
 
C30H32F6N4O
 
6451149 
Major    Inter Info   
[2], [1]
D1398
 
Ribociclib
 
C23H30N8O
 
44631912 
Major    Inter Info   
[1]
D1505
 
Stiripentol
 
C14H18O3
 
5311454 
Major    Inter Info   
[1]
D1653
 
Troleandomycin
 
C41H67NO15
 
202225 
Major    Inter Info   
[5], [6], [1]
D1660
 
Tucatinib
 
C26H24N8O2
 
51039094 
Major    Inter Info   
[5], [6], [1]
D0341
 
Ciprofloxacin
 
C17H18FN3O3
 
2764 
Major    Inter Info   
[1]
D0349
 
Clarithromycin
 
C38H69NO13
 
84029 
Major    Inter Info   
[5], [6], [1]
D0386
 
Conivaptan
 
C32H26N4O2
 
151171 
Major    Inter Info   
[5], [6], [1]
D0413
 
Dalfopristin
 
C34H50N4O9S
 
6323289 
Major    Inter Info   
[2], [1]
D0426
 
Darunavir
 
C27H37N3O7S
 
213039 
Major    Inter Info   
[1]
D0439
 
Delavirdine
 
C22H28N6O3S
 
5625 
Major    Inter Info   
[5], [6], [1]
D0497
 
Diltiazem
 
C22H26N2O4S
 
39186 
Major    Inter Info   
[1]
D0534
 
Dronedarone
 
C31H44N2O5S
 
208898 
Major    Inter Info   
[1]
D0597
 
Erythromycin
 
C37H67NO13
 
12560 
Major    Inter Info   
[1]
D0667
 
Fluconazole
 
C13H12F2N6O
 
3365 
Major    Inter Info   
[1]
D0692
 
Fosamprenavir
 
C25H36N3O9PS
 
131536 
Major    Inter Info   
[1]
D0793
 
Imatinib
 
C29H31N7O
 
5291 
Major    Inter Info   
[1]
D0799
 
Indinavir
 
C36H47N5O4
 
5362440 
Major    Inter Info   
[5], [6], [1]
D0867
 
Itraconazole
 
C35H38Cl2N8O4
 
55283 
Major    Inter Info   
[5], [6], [1]
D0880
 
Ketoconazole
 
C26H28Cl2N4O4
 
456201 
Major    Inter Info   
[5], [6], [1]
D1063
 
Mifepristone
 
C29H35NO2
 
55245 
Major    Inter Info   
[5], [6], [1]
D1117
 
Nefazodone
 
C25H32ClN5O2
 
4449 
Major    Inter Info   
[5], [6], [1]
D1119
 
Nelfinavir
 
C32H45N3O4S
 
64143 
Major    Inter Info   
[5], [6], [1]
D1315
 
Posaconazole
 
C37H42F2N8O4
 
468595 
Major    Inter Info   
[5], [6], [1]
D1444
 
Saquinavir
 
C38H50N6O5
 
441243 
Major    Inter Info   
[5], [6], [1]
D1541
 
Telaprevir
 
C36H53N7O6
 
3010818 
Major    Inter Info   
[5], [6], [1]
D1544
 
Telithromycin
 
C43H65N5O10
 
3002190 
Major    Inter Info   
[5], [6], [1]
D1690
 
Verapamil
 
C27H38N2O4
 
2520 
Major    Inter Info   
[1]
D1706
 
Voriconazole
 
C16H14F3N5O
 
71616 
Major    Inter Info   
[5], [6], [1]
D0002
 
Abametapir (topical)
 
C12H12N2
 
15664 
Moderate    Inter Info   
[12]
D0699
 
Fostamatinib
 
C23H26FN6O9P
 
11671467 
Moderate    Inter Info   
[15]
D0896
 
Larotrectinib
 
C21H22F2N6O2
 
46188928 
Moderate    Inter Info   
[5], [7], [16]
D0899
 
Lefamulin
 
C28H45NO5S
 
25185057 
Moderate    Inter Info   
[17]
D1432
 
Rucaparib
 
C19H18FN3O
 
9931954 
Moderate    Inter Info   
[36]
D1459
 
Selpercatinib
 
C29H31N7O3
 
134436906 
Moderate    Inter Info   
[7], [37]
D1471
 
Simeprevir
 
C38H47N5O7S2
 
24873435 
Moderate    Inter Info   
[38]
D1709
 
Voxelotor
 
C19H19N3O3
 
71602803 
Moderate    Inter Info   
[40]
   CYP450 enzyme induction Drug Num:  52
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0061
 
Aminoglutethimide
 
C13H16N2O2
 
2145 
Moderate    Inter Info   
[1]
D0071
 
Amobarbital
 
C11H18N2O3
 
2164 
Moderate    Inter Info   
[1]
D0095
 
Apalutamide
 
C21H15F4N5O2S
 
24872560 
Moderate    Inter Info   
[1]
D0406
 
Dabrafenib
 
C23H20F3N5O2S2
 
44462760 
Moderate    Inter Info   
[1]
D0545
 
Echinacea
 
NA
 
NA
Moderate    Inter Info   
[5], [14]
D0555
 
Elagolix
 
C32H30F5N3O5
 
11250647 
Moderate    Inter Info   
[1]
D0578
 
Enzalutamide
 
C21H16F4N4O2S
 
15951529 
Moderate    Inter Info   
[1]
D0601
 
Eslicarbazepine
 
C15H14N2O2
 
9881504 
Moderate    Inter Info   
[1]
D0628
 
Etravirine
 
C20H15BrN6O
 
193962 
Moderate    Inter Info   
[1]
D0872
 
Ivosidenib
 
C28H22ClF3N6O3
 
71657455 
Moderate    Inter Info   
[1]
D0901
 
Lemborexant
 
C22H20F2N4O2
 
56944144 
Moderate    Inter Info   
[18], [1], [19]
D0905
 
Lesinurad
 
C17H14BrN3O2S
 
53465279 
Moderate    Inter Info   
[1]
D0953
 
Lorlatinib
 
C21H19FN6O2
 
71731823 
Moderate    Inter Info   
[1]
D0958
 
Lumacaftor
 
C24H18F2N2O5
 
16678941 
Moderate    Inter Info   
[18], [1], [19]
D1258
 
Pexidartinib
 
C20H15ClF3N5
 
25151352 
Moderate    Inter Info   
[1]
D1493
 
Somapacitan
 
C54H95N13O20S2
 
129894493 
Moderate    Inter Info   
[18], [1], [19]
D1495
 
Somatrem
 
C43H72N14O14
 
5487805 
Moderate    Inter Info   
[1]
D1538
 
Tazemetostat
 
C34H44N4O4
 
66558664 
Moderate    Inter Info   
[1]
D1546
 
Telotristat ethyl
 
C27H26ClF3N6O3
 
25181577 
Moderate    Inter Info   
[7], [39]
D1687
 
Vemurafenib
 
C23H18ClF2N3O3S
 
42611257 
Moderate    Inter Info   
[1]
D0178
 
Bexarotene
 
C24H28O2
 
82146 
Moderate    Inter Info   
[1]
D0194
 
Bosentan
 
C27H29N5O6S
 
104865 
Moderate    Inter Info   
[1]
D0224
 
Butabarbital
 
C10H16N2O3
 
2479 
Moderate    Inter Info   
[1]
D0225
 
Butalbital
 
C11H16N2O3
 
2481 
Moderate    Inter Info   
[1]
D0255
 
Carbamazepine
 
C15H12N2O
 
2554 
Moderate    Inter Info   
[1]
D0300
 
Cenobamate
 
C10H10ClN5O2
 
11962412 
Moderate    Inter Info   
[1]
D0432
 
Deferasirox
 
C21H15N3O4
 
214348 
Moderate    Inter Info   
[1]
D0453
 
Dexamethasone
 
C22H29FO5
 
5743 
Moderate    Inter Info   
[1]
D0554
 
Efavirenz
 
C14H9ClF3NO2
 
64139 
Moderate    Inter Info   
[1]
D0639
 
Felbamate
 
C11H14N2O4
 
3331 
Moderate    Inter Info   
[1]
D0697
 
Fosphenytoin
 
C16H15N2O6P
 
56339 
Moderate    Inter Info   
[1]
D0741
 
Griseofulvin
 
C17H17ClO6
 
441140 
Moderate    Inter Info   
[1]
D1040
 
Methylphenobarbital
 
C13H14N2O3
 
8271 
Moderate    Inter Info   
[18], [1], [19]
D1078
 
Mitotane
 
C14H10Cl4
 
4211 
Moderate    Inter Info   
[1]
D1099
 
Nafcillin
 
C21H22N2O5S
 
8982 
Moderate    Inter Info   
[1]
D1128
 
Nevirapine
 
C15H14N4O
 
4463 
Moderate    Inter Info   
[1]
D1198
 
Oxcarbazepine
 
C15H12N2O2
 
34312 
Moderate    Inter Info   
[1]
D1248
 
Pentobarbital
 
C11H18N2O3
 
4737 
Moderate    Inter Info   
[1]
D1265
 
Phenobarbital
 
C12H12N2O3
 
4763 
Moderate    Inter Info   
[1]
D1274
 
Phenylbutazone
 
C19H20N2O2
 
4781 
Moderate    Inter Info   
[1]
D1283
 
Phenytoin
 
C15H12N2O2
 
1775 
Moderate    Inter Info   
[1]
D1340
 
Primidone
 
C12H14N2O2
 
4909 
Moderate    Inter Info   
[1]
D1399
 
Rifabutin
 
C46H62N4O11
 
135398743 
Moderate    Inter Info   
[1]
D1400
 
Rifampicin
 
C43H58N4O12
 
135398735 
Moderate    Inter Info   
[18], [1], [19]
D1401
 
Rifapentine
 
C47H64N4O12
 
135403821 
Moderate    Inter Info   
[1]
D1433
 
Rufinamide
 
C10H8F2N4O
 
129228 
Moderate    Inter Info   
[1]
D1453
 
Secobarbital
 
C12H18N2O3
 
5193 
Moderate    Inter Info   
[1]
D1494
 
Somatotropin
 
NA
 
NA
Moderate    Inter Info   
[18], [1], [19]
D1502
 
St. John's Wort
 
NA
 
NA
Moderate    Inter Info   
[1]
D1652
 
Troglitazone
 
C24H27NO5S
 
5591 
Moderate    Inter Info   
[1]
D0106
 
Armodafinil
 
C15H15NO2S
 
9690109 
Minor    Inter Info   
[45], [46], [47], [48], [49]
D1081
 
Modafinil
 
C15H15NO2S
 
4236 
Minor    Inter Info   
[45], [46], [47], [48], [49]
      Pharmacodynamic additive effects
   Additive hypotensive effects Drug Num:  121
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0083
 
Amyl Nitrite
 
C5H11NO2
 
10026 
Major    Inter Info   
[2], [3], [4]
D0860
 
Isosorbide
 
C6H10O4
 
12597 
Major    Inter Info   
[2], [3], [4]
D1408
 
Riociguat
 
C20H19FN8O2
 
11304743 
Major    Inter Info   
[5], [7], [8]
D0861
 
Isosorbide dinitrate
 
C6H8N2O8
 
6883 
Major    Inter Info   
[2], [3], [4]
D0862
 
Isosorbide mononitrate
 
C6H9NO6
 
27661 
Major    Inter Info   
[2], [3], [4]
D1146
 
Nitroglycerin
 
C3H5N3O9
 
4510 
Major    Inter Info   
[2], [3], [4]
D1147
 
Nitroprusside
 
C5FeN6O
 
11953891 
Major    Inter Info   
[2], [3], [4]
D0010
 
Acebutolol
 
C18H28N2O4
 
1978 
Moderate    Inter Info   
[3], [1], [4]
D0012
 
Acetazolamide
 
C4H6N4O3S2
 
1986 
Moderate    Inter Info   
[3], [1], [4]
D0036
 
Alfuzosin
 
C19H27N5O4
 
2092 
Moderate    Inter Info   
[2], [1]
D0046
 
Alprostadil
 
C20H34O5
 
5280723 
Moderate    Inter Info   
[3], [1], [4]
D0058
 
Amiloride
 
C6H8ClN7O
 
16231 
Moderate    Inter Info   
[3], [1], [4]
D0069
 
Amlodipine
 
C20H25ClN2O5
 
2162 
Moderate    Inter Info   
[3], [1], [4]
D0098
 
Apraclonidine
 
C9H10Cl2N4
 
2216 
Moderate    Inter Info   
[9], [10], [11]
D0117
 
Atenolol
 
C14H22N2O3
 
2249 
Moderate    Inter Info   
[3], [1], [4]
D0038
 
Aliskiren
 
C30H53N3O6
 
5493444 
Moderate    Inter Info   
[3], [1], [4]
D0053
 
Ambrisentan
 
C22H22N2O4
 
6918493 
Moderate    Inter Info   
[3], [1], [4]
D0138
 
Azilsartan medoxomil
 
C30H24N4O8
 
135409642 
Moderate    Inter Info   
[3], [1], [4]
D0245
 
Canagliflozin
 
C24H25FO5S
 
24812758 
Moderate    Inter Info   
[5], [7], [13]
D0418
 
Dapagliflozin
 
C21H25ClO6
 
9887712 
Moderate    Inter Info   
[5], [7], [13]
D0565
 
Empagliflozin
 
C23H27ClO7
 
11949646 
Moderate    Inter Info   
[5], [7], [13]
D0864
 
Isoxsuprine
 
C18H23NO3
 
3783 
Moderate    Inter Info   
[3], [1], [4]
D0911
 
Levamlodipine
 
C20H25ClN2O5
 
9822750 
Moderate    Inter Info   
[3], [1], [4]
D1148
 
Nitrous acid
 
HNO2
 
24529 
Moderate    Inter Info   
[20], [21], [22]
D1211
 
Ozanimod
 
C23H24N4O3
 
52938427 
Moderate    Inter Info   
[23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35]
D1437
 
Safinamide
 
C17H19FN2O2
 
131682 
Moderate    Inter Info   
[23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35]
D0156
 
Benazepril
 
C24H28N2O5
 
5362124 
Moderate    Inter Info   
[3], [1], [4]
D0158
 
Bendroflumethiazide
 
C15H14F3N3O4S2
 
2315 
Moderate    Inter Info   
[3], [1], [4]
D0166
 
Benzthiazide
 
C15H14ClN3O4S3
 
2343 
Moderate    Inter Info   
[3], [1], [4]
D0170
 
Bepridil
 
C24H34N2O
 
2351 
Moderate    Inter Info   
[3], [1], [4]
D0173
 
Betaxolol
 
C18H29NO3
 
2369 
Moderate    Inter Info   
[3], [1], [4]
D0188
 
Bisoprolol
 
C18H31NO4
 
2405 
Moderate    Inter Info   
[3], [1], [4]
D0205
 
Brimonidine (ophthalmic)
 
C11H10BrN5
 
2435 
Moderate    Inter Info   
[9], [10], [11]
D0206
 
Brimonidine (topical)
 
C11H10BrN5
 
2435 
Moderate    Inter Info   
[9], [10], [11]
D0217
 
Bumetanide
 
C17H20N2O5S
 
2471 
Moderate    Inter Info   
[3], [1], [4]
D0254
 
Captopril
 
C9H15NO3S
 
44093 
Moderate    Inter Info   
[3], [1], [4]
D0265
 
Carteolol
 
C16H24N2O3
 
2583 
Moderate    Inter Info   
[3], [1], [4]
D0267
 
Carvedilol
 
C24H26N2O4
 
2585 
Moderate    Inter Info   
[3], [1], [4]
D0321
 
Chlorothiazide
 
C7H6ClN3O4S2
 
2720 
Moderate    Inter Info   
[3], [1], [4]
D0326
 
Chlorthalidone
 
C14H11ClN2O4S
 
2732 
Moderate    Inter Info   
[3], [1], [4]
D0352
 
Clevidipine
 
C21H23Cl2NO6
 
153994 
Moderate    Inter Info   
[3], [1], [4]
D0363
 
Clonidine
 
C9H9Cl2N3
 
2803 
Moderate    Inter Info   
[3], [1], [4]
D0396
 
Cyclandelate
 
C17H24O3
 
2893 
Moderate    Inter Info   
[3], [1], [4]
D0444
 
Deserpidine
 
C32H38N2O8
 
8550 
Moderate    Inter Info   
[3], [1], [4]
D0474
 
Diazoxide
 
C8H7ClN2O2S
 
3019 
Moderate    Inter Info   
[3], [1], [4]
D0479
 
Diclofenamide
 
C6H6Cl2N2O4S2
 
3038 
Moderate    Inter Info   
[3], [1], [4]
D0524
 
Doxazosin
 
C23H25N5O5
 
3157 
Moderate    Inter Info   
[2], [1]
D0567
 
Enalapril
 
C20H28N2O5
 
5388962 
Moderate    Inter Info   
[3], [1], [4]
D0585
 
Eplerenone
 
C24H30O6
 
443872 
Moderate    Inter Info   
[3], [1], [4]
D0586
 
Epoprostenol
 
C20H32O5
 
5282411 
Moderate    Inter Info   
[3], [1], [4]
D0587
 
Eprosartan
 
C23H24N2O4S
 
5281037 
Moderate    Inter Info   
[3], [1], [4]
D0602
 
Esmolol
 
C16H25NO4
 
59768 
Moderate    Inter Info   
[3], [1], [4]
D0613
 
Etacrynic acid
 
C13H12Cl2O4
 
3278 
Moderate    Inter Info   
[3], [1], [4]
D0617
 
Ethanol
 
C2H6O
 
702 
Moderate    Inter Info   
[7], [2], [3], [1], [4]
D0640
 
Felodipine
 
C18H19Cl2NO4
 
3333 
Moderate    Inter Info   
[3], [1], [4]
D0644
 
Fenoldopam
 
C16H16ClNO3
 
3341 
Moderate    Inter Info   
[3], [1], [4]
D0695
 
Fosinopril
 
C30H46NO7P
 
55891 
Moderate    Inter Info   
[3], [1], [4]
D0704
 
Furosemide
 
C12H11ClN2O5S
 
3440 
Moderate    Inter Info   
[3], [1], [4]
D0742
 
Guanabenz
 
C8H8Cl2N4
 
5702063 
Moderate    Inter Info   
[3], [1], [4]
D0743
 
Guanadrel
 
C10H19N3O2
 
38521 
Moderate    Inter Info   
[3], [1], [4]
D0744
 
Guanethidine
 
C10H22N4
 
3518 
Moderate    Inter Info   
[3], [1], [4]
D0745
 
Guanfacine
 
C9H9Cl2N3O
 
3519 
Moderate    Inter Info   
[3], [1], [4]
D0770
 
Hydralazine
 
C8H8N4
 
3637 
Moderate    Inter Info   
[3], [1], [4]
D0771
 
Hydrochlorothiazide
 
C7H8ClN3O4S2
 
3639 
Moderate    Inter Info   
[3], [1], [4]
D0775
 
Hydroflumethiazide
 
C8H8F3N3O4S2
 
3647 
Moderate    Inter Info   
[3], [1], [4]
D0792
 
Iloprost
 
C22H32O4
 
5311181 
Moderate    Inter Info   
[3], [1], [4]
D0798
 
Indapamide
 
C16H16ClN3O3S
 
3702 
Moderate    Inter Info   
[3], [1], [4]
D0844
 
Irbesartan
 
C25H28N6O
 
3749 
Moderate    Inter Info   
[3], [1], [4]
D0853
 
Isocarboxazid
 
C12H13N3O2
 
3759 
Moderate    Inter Info   
[23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35]
D0865
 
Isradipine
 
C19H21N3O5
 
3784 
Moderate    Inter Info   
[3], [1], [4]
D0884
 
Labetalol
 
C19H24N2O3
 
3869 
Moderate    Inter Info   
[3], [1], [4]
D0933
 
Linezolid
 
C16H20FN3O4
 
441401 
Moderate    Inter Info   
[23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35]
D0938
 
Lisinopril
 
C21H31N3O5
 
5362119 
Moderate    Inter Info   
[3], [1], [4]
D0942
 
Lofexidine
 
C11H12Cl2N2O
 
30668 
Moderate    Inter Info   
[3], [1], [4]
D0954
 
Losartan
 
C22H23ClN6O
 
3961 
Moderate    Inter Info   
[3], [1], [4]
D1018
 
Methazolamide
 
C5H8N4O3S2
 
4100 
Moderate    Inter Info   
[3], [1], [4]
D1035
 
Methyldopa
 
C10H13NO4
 
38853 
Moderate    Inter Info   
[3], [1], [4]
D1048
 
Metolazone
 
C16H16ClN3O3S
 
4170 
Moderate    Inter Info   
[3], [1], [4]
D1049
 
Metoprolol
 
C15H25NO3
 
4171 
Moderate    Inter Info   
[3], [1], [4]
D1848
 
Minoxidil (topical)
 
C9H15N5O
 
4201 
Moderate    Inter Info   
[42], [43]
D1082
 
Moexipril
 
C27H34N2O7
 
91270 
Moderate    Inter Info   
[3], [1], [4]
D1098
 
Nadolol
 
C17H27NO4
 
39147 
Moderate    Inter Info   
[3], [1], [4]
D1114
 
Nebivolol
 
C22H25F2NO4
 
71301 
Moderate    Inter Info   
[3], [1], [4]
D1125
 
Nesiritide
 
C143H244N50O42S4
 
53325981 
Moderate    Inter Info   
[3], [1], [4]
D1130
 
Nicardipine
 
C26H29N3O6
 
4474 
Moderate    Inter Info   
[3], [1], [4]
D1134
 
Nifedipine
 
C17H18N2O6
 
4485 
Moderate    Inter Info   
[3], [1], [4]
D1138
 
Nimodipine
 
C21H26N2O7
 
4497 
Moderate    Inter Info   
[3], [1], [4]
D1141
 
Nisoldipine
 
C20H24N2O6
 
4499 
Moderate    Inter Info   
[3], [1], [4]
D1170
 
Olmesartan
 
C24H26N6O3
 
158781 
Moderate    Inter Info   
[3], [1], [4]
D1223
 
Papaverine
 
C20H21NO4
 
4680 
Moderate    Inter Info   
[3], [1], [4]
D1244
 
Penbutolol
 
C18H29NO2
 
37464 
Moderate    Inter Info   
[3], [1], [4]
D1251
 
Pentoxifylline
 
C13H18N4O3
 
4740 
Moderate    Inter Info   
[44]
D1256
 
Perindopril
 
C19H32N2O5
 
107807 
Moderate    Inter Info   
[3], [1], [4]
D1263
 
Phenelzine
 
C8H12N2
 
3675 
Moderate    Inter Info   
[23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35]
D1267
 
Phenoxybenzamine
 
C18H22ClNO
 
4768 
Moderate    Inter Info   
[2], [1]
D1271
 
Phentolamine
 
C17H19N3O
 
5775 
Moderate    Inter Info   
[2], [1]
D1293
 
Pindolol
 
C14H20N2O2
 
4828 
Moderate    Inter Info   
[3], [1], [4]
D1331
 
Prazosin
 
C19H21N5O4
 
4893 
Moderate    Inter Info   
[2], [1]
D1345
 
Procarbazine
 
C12H19N3O
 
4915 
Moderate    Inter Info   
[23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35]
D1357
 
Propranolol
 
C16H21NO2
 
4946 
Moderate    Inter Info   
[3], [1], [4]
D1369
 
Quinapril
 
C25H30N2O5
 
54892 
Moderate    Inter Info   
[3], [1], [4]
D1379
 
Ramipril
 
C23H32N2O5
 
5362129 
Moderate    Inter Info   
[3], [1], [4]
D1385
 
Rasagiline
 
C12H13N
 
3052776 
Moderate    Inter Info   
[23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35]
D1393
 
Reserpine
 
C33H40N2O9
 
5770 
Moderate    Inter Info   
[3], [1], [4]
D1455
 
Selegiline
 
C13H17N
 
26757 
Moderate    Inter Info   
[23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35]
D1466
 
Silodosin
 
C25H32F3N3O4
 
5312125 
Moderate    Inter Info   
[2], [1]
D1498
 
Sotalol
 
C12H20N2O3S
 
5253 
Moderate    Inter Info   
[3], [1], [4]
D1501
 
Spironolactone
 
C24H32O4S
 
5833 
Moderate    Inter Info   
[3], [1], [4]
D1534
 
Tamsulosin
 
C20H28N2O5S
 
129211 
Moderate    Inter Info   
[2], [1]
D1545
 
Telmisartan
 
C33H30N4O2
 
65999 
Moderate    Inter Info   
[3], [1], [4]
D1552
 
Terazosin
 
C19H25N5O4
 
5401 
Moderate    Inter Info   
[2], [1]
D1585
 
Timolol
 
C13H24N4O3S
 
33624 
Moderate    Inter Info   
[3], [1], [4]
D1602
 
Tolazoline
 
C10H12N2
 
5504 
Moderate    Inter Info   
[3], [1], [4]
D1611
 
Torasemide
 
C16H20N4O3S
 
41781 
Moderate    Inter Info   
[3], [1], [4]
D1618
 
Trandolapril
 
C24H34N2O5
 
5484727 
Moderate    Inter Info   
[3], [1], [4]
D1620
 
Tranylcypromine
 
C9H11N
 
19493 
Moderate    Inter Info   
[23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35]
D1625
 
Treprostinil
 
C23H34O5
 
6918140 
Moderate    Inter Info   
[3], [1], [4]
D1631
 
Triamterene
 
C12H11N7
 
5546 
Moderate    Inter Info   
[3], [1], [4]
D1633
 
Trichlormethiazide
 
C8H8Cl3N3O4S2
 
5560 
Moderate    Inter Info   
[3], [1], [4]
D1643
 
Trimethaphan
 
C22H25N2OS+
 
23576 
Moderate    Inter Info   
[3], [1], [4]
D1679
 
Valsartan
 
C24H29N5O3
 
60846 
Moderate    Inter Info   
[3], [1], [4]
   Increased risk of other adverse reactions (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0952
 
Lorcaserin
 
C11H14ClN
 
11658860 
Moderate    Inter Info   
[41]
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