Details of Drug

Details of Drug

 Drug General Information (ID: D0062)
  Drug Name
Aminolevulinic acid
  Drug Type Small molecule
  Drug Synonymous
Aminolevulinic acid; 5-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid; 106-60-5; 5-Aminolevulinate; delta-aminolevulinic acid; Pentanoic acid, 5-amino-4-oxo-; Aladerm; 5-Amino-4-oxovaleric acid; Kerastick; Ameluz; Aminolevulinate; 5-ALA; delta-ALA; 5-Amino-4-oxopentanoate; 5-amino-levulinate; 5-amino-levulinic acid; 5-amino-4-oxo-pentanoic acid; CCRIS 8958; UNII-88755TAZ87; EINECS 203-414-1; Levulinic acid, 5-amino-; CHEMBL601; 4-oxo-5-amino-pentanoic acid; CHEBI:17549; ZGXJTSGNIOSYLO-UHFFFAOYSA-N; 88755TAZ87; Levulan (TN)
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  Disease Class ED80: Acne vulgaris; EK90: Epidermal dysplasias
  Therapeutic Class Malignancy Photosensitizers
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C5H9NO3
  InChI 1S/C5H9NO3/c6-3-4(7)1-2-5(8)9/h1-3,6H2,(H,8,9)
  InChIKey ZGXJTSGNIOSYLO-UHFFFAOYSA-N
  Canonical SMILES C(CC(=O)O)C(=O)CN
  External Link
Pubchem ID 137
CAS Number 106-60-5
CHEBI ID 17549
TTD ID D0Y7ZD
INTEDE ID DR0088
VARIDT ID DR00057

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
BM075  Increased risk of photosensitivity reactions
  Relation Graph
 Full list of drugs interacting with Aminolevulinic acid
      Pharmacodynamic additive effects
   Increased risk of photosensitivity reactions Drug Num:  94
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0012
 
Acetazolamide
 
C4H6N4O3S2
 
1986 
Major    Inter Info   
[1], [2]
D0018
 
Acitretin
 
C21H26O3
 
5284513 
Major    Inter Info   
[1], [2]
D0024
 
Adapalene (topical)
 
C28H28O3
 
60164 
Major    Inter Info   
[1], [2]
D0039
 
Alitretinoin (topical)
 
C20H28O2
 
449171 
Major    Inter Info   
[1], [2]
D0026
 
Afatinib
 
C24H25ClFN5O3
 
10184653 
Major    Inter Info   
[1], [2]
D0031
 
Alectinib
 
C30H34N4O2
 
49806720 
Major    Inter Info   
[1], [2]
D0066
 
Amiodarone
 
C25H29I2NO3
 
2157 
Major    Inter Info   
[1], [2]
D0129
 
Avapritinib
 
C26H27FN10
 
118023034 
Major    Inter Info   
[1], [2]
D0180
 
Bicalutamide
 
C18H14F4N2O4S
 
2375 
Major    Inter Info   
[1], [2]
D0217
 
Bumetanide
 
C17H20N2O5S
 
2471 
Major    Inter Info   
[1], [2]
D0251
 
Capmatinib
 
C23H17FN6O
 
25145656 
Major    Inter Info   
[1], [2]
D0321
 
Chlorothiazide
 
C7H6ClN3O4S2
 
2720 
Major    Inter Info   
[1], [2]
D0376
 
Cobimetinib
 
C21H21F3IN3O2
 
16222096 
Major    Inter Info   
[1], [2]
D0406
 
Dabrafenib
 
C23H20F3N5O2S2
 
44462760 
Major    Inter Info   
[1], [2]
D0589
 
Eravacycline
 
C27H31FN4O8
 
54726192 
Major    Inter Info   
[1], [2]
D0613
 
Etacrynic acid
 
C13H12Cl2O4
 
3278 
Major    Inter Info   
[1], [2]
D0712
 
Gatifloxacin
 
C19H22FN3O4
 
5379 
Major    Inter Info   
[1], [2]
D0716
 
Gemifloxacin
 
C18H20FN5O4
 
9571107 
Major    Inter Info   
[1], [2]
D0728
 
Glipizide
 
C21H27N5O4S
 
3478 
Major    Inter Info   
[1], [2]
D0730
 
Glyburide
 
C23H28ClN3O5S
 
3488 
Major    Inter Info   
[1], [2]
D0771
 
Hydrochlorothiazide
 
C7H8ClN3O4S2
 
3639 
Major    Inter Info   
[1], [2]
D0786
 
Ibuprofen
 
C13H18O2
 
3672 
Major    Inter Info   
[1], [2]
D0863
 
Isotretinoin
 
C20H28O2
 
5282379 
Major    Inter Info   
[1], [2]
D0881
 
Ketoprofen
 
C16H14O3
 
3825 
Major    Inter Info   
[1], [2]
D0894
 
Lapatinib
 
C29H26ClFN4O4S
 
208908 
Major    Inter Info   
[1], [2]
D0919
 
Levofloxacin
 
C18H20FN3O4
 
149096 
Major    Inter Info   
[1], [2]
D1010
 
Mesoridazine
 
C21H26N2OS2
 
4078 
Major    Inter Info   
[1], [2]
D1033
 
Methyl aminolevulinate (topical)
 
C6H11NO3
 
157922 
Major    Inter Info   
[1], [2]
D1070
 
Minocycline
 
C23H27N3O7
 
54675783 
Major    Inter Info   
[1], [2]
D1071
 
Minocycline (topical)
 
C23H27N3O7
 
54675783 
Major    Inter Info   
[1], [2]
D1155
 
Norfloxacin
 
C16H18FN3O3
 
4539 
Major    Inter Info   
[1], [2]
D1165
 
Ofloxacin
 
C18H20FN3O4
 
4583 
Major    Inter Info   
[1], [2]
D1175
 
Omadacycline
 
C29H40N4O7
 
54697325 
Major    Inter Info   
[1], [2]
D1220
 
Panitumumab
 
NA
 
NA
Major    Inter Info   
[1], [2]
D1299
 
Pirfenidone
 
C12H11NO
 
40632 
Major    Inter Info   
[1], [2]
D1311
 
Polythiazide
 
C11H13ClF3N3O4S3
 
4870 
Major    Inter Info   
[1], [2]
D1352
 
Promethazine
 
C17H20N2S
 
4927 
Major    Inter Info   
[1], [2]
D1445
 
Sarecycline
 
C24H29N3O8
 
54681908 
Major    Inter Info   
[1], [2]
D1471
 
Simeprevir
 
C38H47N5O7S2
 
24873435 
Major    Inter Info   
[1], [2]
D1502
 
St. John's Wort
 
NA
 
NA
Major    Inter Info   
[1], [2]
D1516
 
Sulfamethoxazole
 
C10H11N3O3S
 
5329 
Major    Inter Info   
[1], [2]
D1592
 
Tipranavir
 
C31H33F3N2O5S
 
54682461 
Major    Inter Info   
[1], [2]
D1603
 
Tolbutamide
 
C12H18N2O3S
 
5505 
Major    Inter Info   
[1], [2]
D1636
 
Trifarotene (topical)
 
C29H33NO4
 
11518241 
Major    Inter Info   
[1], [2]
D1681
 
Vandetanib
 
C22H24BrFN4O2
 
3081361 
Major    Inter Info   
[1], [2]
D1687
 
Vemurafenib
 
C23H18ClF2N3O3S
 
42611257 
Major    Inter Info   
[1], [2]
D0158
 
Bendroflumethiazide
 
C15H14F3N3O4S2
 
2315 
Major    Inter Info   
[1], [2]
D0178
 
Bexarotene
 
C24H28O2
 
82146 
Major    Inter Info   
[1], [2]
D0179
 
Bexarotene (topical)
 
C24H28O2
 
82146 
Major    Inter Info   
[1], [2]
D0298
 
Celecoxib
 
C17H14F3N3O2S
 
2662 
Major    Inter Info   
[1], [2]
D0306
 
Cetuximab
 
NA
 
NA
Major    Inter Info   
[1], [2]
D0324
 
Chlorpromazine
 
C17H19ClN2S
 
2726 
Major    Inter Info   
[1], [2]
D0325
 
Chlorpropamide
 
C10H13ClN2O3S
 
2727 
Major    Inter Info   
[1], [2]
D0326
 
Chlorthalidone
 
C14H11ClN2O4S
 
2732 
Major    Inter Info   
[1], [2]
D0341
 
Ciprofloxacin
 
C17H18FN3O3
 
2764 
Major    Inter Info   
[1], [2]
D0419
 
Dapsone
 
C12H12N2O2S
 
2955 
Major    Inter Info   
[1], [2]
D0441
 
Demeclocycline
 
C21H21ClN2O8
 
54680690 
Major    Inter Info   
[1], [2]
D0530
 
Doxycycline
 
C22H24N2O8
 
54671203 
Major    Inter Info   
[1], [2]
D0595
 
Erlotinib
 
C22H23N3O4
 
176870 
Major    Inter Info   
[1], [2]
D0645
 
Fenoprofen
 
C15H14O3
 
3342 
Major    Inter Info   
[1], [2]
D0678
 
Fluphenazine
 
C22H26F3N3OS
 
3372 
Major    Inter Info   
[1], [2]
D0680
 
Flurbiprofen
 
C15H13FO2
 
3394 
Major    Inter Info   
[1], [2]
D0704
 
Furosemide
 
C12H11ClN2O5S
 
3440 
Major    Inter Info   
[1], [2]
D0713
 
Gefitinib
 
C22H24ClFN4O3
 
123631 
Major    Inter Info   
[1], [2]
D0727
 
Glimepiride
 
C24H34N4O5S
 
3476 
Major    Inter Info   
[1], [2]
D0741
 
Griseofulvin
 
C17H17ClO6
 
441140 
Major    Inter Info   
[1], [2]
D0775
 
Hydroflumethiazide
 
C8H8F3N3O4S2
 
3647 
Major    Inter Info   
[1], [2]
D0793
 
Imatinib
 
C29H31N7O
 
5291 
Major    Inter Info   
[1], [2]
D0796
 
Imiquimod (topical)
 
C14H16N4
 
57469 
Major    Inter Info   
[1], [2]
D0798
 
Indapamide
 
C16H16ClN3O3S
 
3702 
Major    Inter Info   
[1], [2]
D1025
 
Methotrexate
 
C20H22N8O5
 
126941 
Major    Inter Info   
[1], [2]
D1028
 
Methoxsalen
 
C12H8O4
 
4114 
Major    Inter Info   
[1], [2]
D1029
 
Methoxsalen (topical)
 
C12H8O4
 
4114 
Major    Inter Info   
[1], [2]
D1048
 
Metolazone
 
C16H16ClN3O3S
 
4170 
Major    Inter Info   
[1], [2]
D1092
 
Moxifloxacin
 
C21H24FN3O4
 
152946 
Major    Inter Info   
[1], [2]
D1109
 
Naproxen
 
C14H14O3
 
156391 
Major    Inter Info   
[1], [2]
D1257
 
Perphenazine
 
C21H26ClN3OS
 
4748 
Major    Inter Info   
[1], [2]
D1346
 
Prochlorperazine
 
C20H24ClN3S
 
4917 
Major    Inter Info   
[1], [2]
D1513
 
Sulfadiazine
 
C10H10N4O2S
 
5215 
Major    Inter Info   
[1], [2]
D1517
 
Sulfasalazine
 
C18H14N4O5S
 
5339 
Major    Inter Info   
[1], [2]
D1519
 
Sulfisoxazole
 
C11H13N3O3S
 
5344 
Major    Inter Info   
[1], [2]
D1537
 
Tazarotene (topical)
 
C21H21NO2S
 
5381 
Major    Inter Info   
[1], [2]
D1564
 
Tetracycline
 
C22H24N2O8
 
54675776 
Major    Inter Info   
[1], [2]
D1574
 
Thioridazine
 
C21H26N2S2
 
5452 
Major    Inter Info   
[1], [2]
D1582
 
Tigecycline
 
C29H39N5O8
 
54686904 
Major    Inter Info   
[1], [2]
D1601
 
Tolazamide
 
C14H21N3O3S
 
5503 
Major    Inter Info   
[1], [2]
D1611
 
Torasemide
 
C16H20N4O3S
 
41781 
Major    Inter Info   
[1], [2]
D1626
 
Tretinoin
 
C20H28O2
 
444795 
Major    Inter Info   
[1], [2]
D1627
 
Tretinoin (topical)
 
C20H28O2
 
444795 
Major    Inter Info   
[1], [2]
D1637
 
Trifluoperazine
 
C21H24F3N3S
 
5566 
Major    Inter Info   
[1], [2]
D1657
 
Trovafloxacin
 
C20H15F3N4O3
 
62959 
Major    Inter Info   
[1], [2]
D1691
 
Verteporfin
 
C82H84N8O16
 
11980904 
Major    Inter Info   
[1], [2]
D1706
 
Voriconazole
 
C16H14F3N5O
 
71616 
Major    Inter Info   
[1], [2]
D1314
 
Porfimer sodium
 
C68H74N8O11
 
135577896 
Moderate    Inter Info   
[3], [4], [5]
References
1 Product Information. Nulibry (fosdenopterin). Origin Biosciences Inc, Boston, MA.
2 Product Information. Gleolan (aminolevulinic acid). NX Development Corp, Lexington, KY.
3 Blakely KM, Drucker AM, Rosen CF "Drug-induced photosensitivity-an update: Culprit drugs, prevention and management." Drug Saf 42 (2019): 827-47. [PMID: 30888626]
4 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
5 Product Information. Photofrin (porfimer). Sanofi Winthrop Pharmaceuticals, New York, NY.