Drug General Information (ID: DDIYA2QVDO)
  Drug Name Insulin human (zinc extended) Drug Info Dexamethasone (ophthalmic) Drug Info
  Drug Type Hormones Small molecule
  Therapeutic Class Insulin/Antidiabetic Agents Antiinflammatory Agents
  Structure

 Mechanism of Insulin human (zinc extended)-Dexamethasone (ophthalmic) Interaction (Severity Level: Minor)
     Antagonize the effect of antidiabetic agents Click to Show/Hide Mechanism Graph
Could Not Find 2D Structure
      Drug Name Insulin human (zinc extended) Dexamethasone (ophthalmic)
      Mechanism 1 Antidiabetic agent Hyperglycemia
      Key Mechanism Factor 1
Factor Name Antidiabetic agents
Factor Description The hypoglycemic effect of antidiabetes may be reduced, leading to higher blood glucose, increased blood glucose fluctuations, and the possibility of hyperglycemic complications
      Mechanism Description
  • Antagonize the effect of Insulin human (zinc extended) when combined with Dexamethasone (ophthalmic) 
      Mechanism 2 Antidiabetic agent Hyperglycemic effects
      Key Mechanism Factor 2
Factor Name Antidiabetic agents
Factor Description The hypoglycemic effect of antidiabetes may be reduced, leading to higher blood glucose, increased blood glucose fluctuations, and the possibility of hyperglycemic complications
      Mechanism Description
  • Antagonize the effect of Insulin human (zinc extended) when combined with Dexamethasone (ophthalmic) 

References
1 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2 Jerntorp P, Almer LO "Chlorpropamide-alcohol flushing in relation to macroangiopathy and peripheral neuropathy in non-insulin dependent diabetes." Acta Med Scand 656 (1981): 33-6. [PMID: 6953748]
3 Skillman TG, Feldman JM "The pharmacology of sulfonylureas." Am J Med 70 (1981): 361-72. [PMID: 6781341]