Drug General Information (ID: DDIVO7D5NA)
  Drug Name Ketorolac (ophthalmic) Drug Info Prednisolone (ophthalmic) Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Analgesics Antineoplastics
  Structure

 Mechanism of Ketorolac (ophthalmic)-Prednisolone (ophthalmic) Interaction (Severity Level: Moderate)
     Increased risk of other adverse reactions (Unspecific) Click to Show/Hide Mechanism Graph
      Drug Name Ketorolac (ophthalmic) Prednisolone (ophthalmic)
      Mechanism Slow/delay healing Slow/delay healing
      Key Mechanism Factor 1
Factor Name Adverse reactions
Factor Description An adverse reaction is an unexpected negative reaction to a medication or treatment that happens even when it's used correctly.
      Mechanism Description
  • Increased risk of adverse reactions by the combination of Ketorolac (ophthalmic) and Prednisolone (ophthalmic) 

Recommended Action
      Management The use of ophthalmic NSAIDs in combination with ophthalmic corticosteroids should be avoided unless benefits outweigh the potential risks.

References
1 Product Information. Acular (ketorolac). Allergan Inc, Irvine, CA.
2 Product Information. Nevanac (nepafenac ophthalmic). Alcon Laboratories Inc, Fort Worth, TX.
3 Product Information. Xibrom (bromfenac ophthalmic). ISTA Pharmaceuticals, Irvine, CA.