Drug General Information (ID: DDIUX50H23)
  Drug Name Griseofulvin Drug Info Acetylsalicylic acid Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Antifungal Agents Analgesics
  Structure

 Mechanism of Griseofulvin-Acetylsalicylic acid Interaction (Severity Level: Minor)
     Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph
      Drug Name Griseofulvin Acetylsalicylic acid
      Mechanism Decrease absorption of salicylate Salicylate
      Key Mechanism Factor 1
Factor Name Pharmacokinetic
Factor Description Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
      Mechanism Description
  • Altered absorption of Acetylsalicylic acid caused by Griseofulvin 

References
1 Phillips KR, Wideman SD, Cochran EB, Becker JA "Griseofulvin significantly decreases serum salicylate concentrations." Pediatr Infect Dis J 12 (1993): 350-2. [PMID: 8483633]
2 Product Information. Persantine (dipyridamole). Boehringer-Ingelheim, Ridgefield, CT.
3 Ranhosky A, Kempthorne-Rawson J, the Intravenous Dipyridamole Thallium Imaging Study Group "The safety of intravenous dipyridamole thallium myocardial perfusion imaging." Circulation 81 (1990): 1205-9. [PMID: 2107985]