Drug General Information (ID: DDIUK1FMIE)
Drug Name			Simvastatin		Drug Info		Albiglutide		Drug Info
Drug Type		Small molecule				Protein/peptide
Therapeutic Class		Statins/Antihyperlipidemic Agents				Glp-1 Agonists/Antidiabetic Agents
Structure

Mechanism of Simvastatin-Albiglutide Interaction (Severity Level: Minor)
Altered gastrointestinal dynamics Click to Show/Hide Mechanism Graph
Drug Name		Simvastatin				Albiglutide
Mechanism		Absorption affected by delayed gastric emptying				Delayed gastric emptying
Key Mechanism Factor 1
		Factor Name		Gastrointestinal Motility
		Factor Description		Gastrointestinal motility is an important factor in determining the absorption of orally administered drugs, and it controls the residence time of the drug in the digestive tract.
Mechanism Description		Altered absorption of Simvastatin due to GI dynamics variation caused by Albiglutide

References
1	EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports.".
2	Product Information. Tanzeum (albiglutide). GlaxoSmithKline, Research Triangle Park, NC.