Drug General Information (ID: DDITED7XZS)
Drug Name			Fluoxymesterone		Drug Info		Thyroid, porcine		Drug Info
Drug Type		Small molecule				Hormones
Therapeutic Class		Hormones/Antineoplastics				Thyroid Drugs

Mechanism of Fluoxymesterone-Thyroid, porcine Interaction (Severity Level: Moderate)
Potentiated the pharmacological effects (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Fluoxymesterone				Thyroid, porcine
Mechanism		Increase the risk of hyperthyroidism in patients receiving thyroid hormone replacement therapy				Thyroid hormone
Key Mechanism Factor 1
		Factor Name		Pharmacodynamics
		Factor Description		Enhanced pharmacological effects leading to increased adverse reactions.
Mechanism Description		Potentiate the pharmacologic effects by the combination of Fluoxymesterone and Thyroid, porcine

Recommended Action
Management		Clinical and laboratory monitoring of thyroid function may be necessary, as may a 25% to 50% reduction in thyroid hormone dosage.

References
1	Product Information. Armour thyroid (thyroid desiccated). Forest Pharmaceuticals, St. Louis, MO.
2	Wohlt PD, Zheng L, Gunderson S, Balzar SA, Johnson BD, Fish JT "Recommendations for the use of medications with continuous enteral nutrition." Am J Health Syst Pharm 66 (2009): 1438-67. [PMID: 19667002]
3	Arafah BM "Decreased levothyroxine requirement in women with hypothyroidism during androgen therapy for breast cancer." Ann Intern Med 121 (1994): 247-51