Drug General Information (ID: DDITDQU7XV)
Drug Name			Phenylephrine (ophthalmic)		Drug Info		Halothane		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Mydriatics/Decongestants				Anesthetics
Structure

Mechanism of Phenylephrine (ophthalmic)-Halothane Interaction (Severity Level: Major)
Increased risk of other adverse reactions (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Phenylephrine (ophthalmic)				Halothane
Mechanism		Catecholamines				Increase the arrhythmogenic effects of catecholamines
Key Mechanism Factor 1
		Factor Name		Adverse reactions
		Factor Description		An adverse reaction is an unexpected negative reaction to a medication or treatment that happens even when it's used correctly.
Mechanism Description		Increased risk of adverse reactions by the combination of Phenylephrine (ophthalmic) and Halothane

Recommended Action
Management		This combination should be avoided or used very cautiously and the patient's hemodynamic status should be closely monitored.

References
1	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2	Agencia Espaola de Medicamentos y Productos Sanitarios Healthcare "Centro de informacion online de medicamentos de la AEMPS - CIMA."
3	Product Information. Neo-Synephrine (phenylephrine). Abbott Pharmaceutical, Abbott Park, IL.