Drug General Information (ID: DDIT9S2F85)
  Drug Name Vibrio cholerae CVD 103-HgR strain live antigen (live) Drug Info Tedizolid Drug Info
  Drug Type Vaccine Small molecule
  Therapeutic Class Vaccines Oxazolidinone Antibiotics

 Mechanism of Vibrio cholerae CVD 103-HgR strain live antigen (live)-Tedizolid Interaction (Severity Level: Major)
     Antagonize the effect of vaccine/toxoid Click to Show/Hide Mechanism Graph
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      Drug Name Vibrio cholerae CVD 103-HgR strain live antigen (live) Tedizolid
      Mechanism Immunomodulatory infective agent Impairs immunomodulatory bacterial infective agent
      Key Mechanism Factor 1
Factor Name Vaccine/toxoid
Factor Description The beneficial effects of the vaccine/toxinoid may be reduced, leading to a diminished or suboptimal immune response.
      Mechanism Description
  • Antagonize the effect of Vibrio cholerae CVD 103-HgR strain live antigen (live) when combined with Tedizolid 

Recommended Action
      Management Live, attenuated cholera vaccine should not be administered during or for at least 14 days after treatment with systemic antibiotics.

References
1 Product Information. Vaxchora (cholera vaccine, live). PaxVax, Miami, FL.