Drug General Information (ID: DDIRC5F7KO)
Drug Name			Edoxaban		Drug Info		Coagulation factor X human		Drug Info
Drug Type		Small molecule				Protein/peptide
Therapeutic Class		Anticoagulants/Factor Xa Inhibitors				Coagulation Modifiers

Mechanism of Edoxaban-Coagulation factor X human Interaction (Severity Level: Moderate)
Antagonize the effect of antithrombotic agents Click to Show/Hide Mechanism Graph
Drug Name		Edoxaban				Coagulation factor X human
Mechanism		Anticoagulant Factor Xa inhibitor				Coagulation factor X
Key Mechanism Factor 1
		Factor Name		Antithrombotic agents
		Factor Description		The beneficial effects of antithrombotic agents are reduced, leading to an increased risk of thromboembolism, stroke and/or myocardial infarction.
Mechanism Description		Antagonize the effect of Edoxaban when combined with Coagulation factor X human

Recommended Action
Management		Concomitant use of coagulation factor X with direct and indirect factor Xa inhibitors should be avoided.

References
1	Product Information. Coagadex (coagulation factor X). Bio Products Laboratory, Raleigh, NC.