Drug General Information (ID: DDIR468ESH)
Drug Name			Iron Dextran		Drug Info		Iron protein succinylate		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Iron Supplement				Iron Supplement

Mechanism of Iron Dextran-Iron protein succinylate Interaction (Severity Level: Moderate)
Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Iron Dextran				Iron protein succinylate
Mechanism		Alters iron absorption				Iron oral
Key Mechanism Factor 1
		Factor Name		Pharmacokinetic
		Factor Description		Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Altered absorption of Iron protein succinylate caused by Iron Dextran

Recommended Action
Management		Parenteral iron preparations should not be administered concomitantly with oral iron preparations. Patients should wait at least 5 days after stopping parenteral iron therapy before taking oral iron supplements.

References
1	Product Information. Accrufer (ferric maltol). Shield Therapeutics, Wilmington, DE.
2	Product Information. Feraheme (ferumoxytol). Alza Pharmaceuticals, Mountain View, CA.
3	Product Information. Ferrlecit (sodium ferric gluconate complex). sanofi-aventis, Bridgewater, NJ.
4	Product Information. INFeD (iron dextran). Schein Pharmaceuticals Inc, Florham Park, NJ.
5	Product Information. Venofer (iron sucrose) American Regent Laboratories Inc, Shirley, NY.