Drug General Information (ID: DDIPFCDBZE)
Drug Name			Nifedipine		Drug Info		Pioglitazone		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Analgesics				Antidiabetic Agents
Structure

Mechanism of Nifedipine-Pioglitazone Interaction (Severity Level: Minor)
Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Nifedipine				Pioglitazone
Mechanism		Nifedipine				Decrease bioavailability of nifedipine
Key Mechanism Factor 1
		Factor Name		Pharmacokinetic
		Factor Description		Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Altered absorption of Nifedipine caused by Pioglitazone

References
1	Product Information. Actos (pioglitazone) Takeda Pharmaceuticals America, Lincolnshire, IL.