| Mechanism of Granisetron-Ketoconazole Interaction
(Severity Level: Minor)
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Decreased metabolism (Unspecific)
Click to Show/Hide Mechanism Graph
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| Drug Name |
Granisetron |
Ketoconazole |
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Mechanism
|
Granisetron |
Inhibit ring oxidation of granisetron |
| Key Mechanism Factor 1 |
| Factor Name |
Pharmacokinetics |
| Factor Description |
Alters the metabolism of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects. |
| Mechanism Description |
- Decreased metabolism of Granisetron caused by Ketoconazole
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