Details of Drug Interaction

Details of Drug-Drug Interaction

 Drug General Information (ID: DDIP4XBE7J)
  Drug Name Thiethylperazine Drug Info Magnesium carbonate Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Antiemetics Antacids
  Structure

 Mechanism of Thiethylperazine-Magnesium carbonate Interaction (Severity Level: Minor)
     Adsorption Click to Show/Hide Mechanism Graph
Could Not Find 2D Structure
      Drug Name Thiethylperazine Magnesium carbonate
      Mechanism Adsorbed by antacids Antacid
      Key Mechanism Factor 1
Factor Name Adsorption
Factor Description Adsorption is a direct drug interaction, usually through adsorption on its surface, resulting in reduced absorption of concomitantly administered drugs in the gastrointestinal tract.
      Mechanism Description
  • Decreased absorption of Thiethylperazine due to adsorption of Magnesium carbonate 

References
1 Covington TR, Lawson LC, Young LL, eds. "Handbook of Nonprescription Drugs. 10th ed." Washington, DC: American Pharmaceutical Association (1993):.
2 Fann WE "Interactions of psychotropic drugs in the elderly." Postgrad Med 53 (1973): 182-6. [PMID: 4144160]
3 Romankiewicz JA "Effects of antacids on gastrointestinal absorption of drugs." Prim Care 3 (1976): 537-50. [PMID: 61596]