Drug General Information (ID: DDIOXITD1S)
Drug Name			Mycophenolic acid		Drug Info		Cefepime		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antiviral Agents				Antibiotics
Structure

Mechanism of Mycophenolic acid-Cefepime Interaction (Severity Level: Moderate)
Altered intestinal flora Click to Show/Hide Mechanism Graph
Drug Name		Mycophenolic acid				Cefepime
Mechanism		Affected by alters GI flora				Alters GI flora
Key Mechanism Factor 1
		Factor Name		Intestinal flora
		Factor Description		The intestinal flora has multiple effects on human health, and altering the intestinal microbiota can affect the absorption of drugs and alter their pharmacological effects.
Mechanism Description		Altered absorption of Mycophenolic acid due to GI flora changes caused by Cefepime

Recommended Action
Management		Close clinical and laboratory monitoring for evidence of diminished immunosuppressive effect of mycophenolic acid is recommended during concomitant therapy with anti-infective agents.

References
1	Product Information. CellCept (mycophenolate mofetil). Roche Laboratories, Nutley, NJ.
2	Product Information. Myfortic (mycophenolic acid). Novartis Pharmaceuticals, East Hanover, NJ.