Drug General Information (ID: DDIOSYK4P7)
Drug Name			Insulin lispro (protamine)		Drug Info		Potassium gluconate		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antidiabetic Agents				Minerals And Electrolytes
Structure

Mechanism of Insulin lispro (protamine)-Potassium gluconate Interaction (Severity Level: Minor)
Increased risk of hypoglycemia Click to Show/Hide Mechanism Graph
Drug Name		Insulin lispro (protamine)				Potassium gluconate
Mechanism		Antidiabetic agent				Reverse glucose intolerance
Key Mechanism Factor 1
		Factor Name		Hypoglycemia
		Factor Description		Hypoglycemia is a condition in which your blood sugar (glucose) level is below the standard range. It causes irregular or rapid heartbeat, pale skin, numbness of the lips, tongue or cheeks, and sweating.
Mechanism Description		Increased risk of hypoglycemia by the combination of Insulin lispro (protamine) and Potassium gluconate

References
1	DeFronzo RA, Cooke CR, Andres R, Faloona GR, Davis PJ "The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man." J Clin Invest 55 (1975): 845-55
2	Hiatt N, Davidson MB, Bonorris G "The effect of potassium chloride infusion on insulin secretion in vivo." Horm Metab Res 4 (1972): 64-8
3	Conn HO "Cirrhosis and diabetes. IV. Effect of potassium chloride administration on glucose and insulin metabolism." Am J Med Sci 259 (1970): 394-404