Drug General Information (ID: DDIMW9J8I1)
Drug Name			Cyclophosphamide		Drug Info		Gallium chloride Ga-67		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antineoplastics				Diagnostic Radiopharmaceuticals
Structure

Mechanism of Cyclophosphamide-Gallium chloride Ga-67 Interaction (Severity Level: Moderate)
Interference of cell/tissue uptake Click to Show/Hide Mechanism Graph
Drug Name		Cyclophosphamide				Gallium chloride Ga-67
Mechanism		Interference with uptake of gallium citrate Ga-67				Gallium citrate Ga-67
Key Mechanism Factor 1
		Factor Name		Pharmacokinetics
		Factor Description		Alters the distribution of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Interference of cell/tissue uptake of Gallium chloride Ga-67 by Cyclophosphamide

Recommended Action
Management		Clinicians should be aware of the potential for an interaction.

References
1	Product Information. Gallium Citrate Ga-67 (gallium citrate 67 Ga (gallium citrate 67Ga)). Bristol-Myers Squibb, Princeton, NJ.