Drug General Information (ID: DDIK34YQGE)
Drug Name			Amiloride		Drug Info		Dalteparin		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Diuretics				Anticoagulants
Structure

Mechanism of Amiloride-Dalteparin Interaction (Severity Level: Moderate)
Increased risk of hyperkalemia Click to Show/Hide Mechanism Graph
Drug Name		Amiloride				Dalteparin
Mechanism		Hyperkalemia				Hyperkalemia
Key Mechanism Factor 1
		Factor Name		Hyperkalemia
		Factor Description		Hyperkalemia is a condition in which the level of potassium in the blood is higher than normal. While mild cases may not produce symptoms, severe hyperkalemia can lead to fatal arrhythmias if left untreated.
Mechanism Description		Increased risk of hyperkalemia by the combination of Amiloride and Dalteparin

Recommended Action
Management		Caution is advised if potassium-sparing diuretics are used with heparin or low molecular weight heparin. Serum potassium levels and renal function should be checked regularly.

References
1	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2	Cerner Multum, Inc. "Australian Product Information.".
3	Agencia Espaola de Medicamentos y Productos Sanitarios Healthcare "Centro de informacion online de medicamentos de la AEMPS - CIMA.".