Drug General Information (ID: DDIJN8MXBP)
Drug Name			Insulin human (isophane)		Drug Info		Benzphetamine		Drug Info
Drug Type		Hormones				Small molecule
Therapeutic Class		Insulin/Antidiabetic Agents				Cns Stimulants
Structure

Mechanism of Insulin human (isophane)-Benzphetamine Interaction (Severity Level: Moderate)
Increased risk of hypoglycemia Click to Show/Hide Mechanism Graph
Drug Name		Insulin human (isophane)				Benzphetamine
Mechanism		Hypoglycemic effects				Hypoglycemic effects
Key Mechanism Factor 1
		Factor Name		Hypoglycemia
		Factor Description		Hypoglycemia is a condition in which your blood sugar (glucose) level is below the standard range. It causes irregular or rapid heartbeat, pale skin, numbness of the lips, tongue or cheeks, and sweating.
Mechanism Description		Increased risk of hypoglycemia by the combination of Insulin human (isophane) and Benzphetamine

Recommended Action
Management		Blood glucose should be closely monitored during weight loss treatment, and appropriate changes made to the antidiabetic drug regimen as needed. Patients should be apprised of the risk of hypoglycemia and be alert to potential signs and symptoms such as headache, dizziness, drowsiness, nervousness, confusion, tremor, hunger, weakness, perspiration, palpitation, and tachycardia.

References
1	Product Information. Didrex (benzphetamine) Pharmacia and Upjohn, Kalamazoo, MI.
2	Product Information. Xenical (orlistat). Roche Laboratories, Nutley, NJ.
3	Product Information. Suprenza (phentermine). Akrimax Pharmaceuticals, Cranford, NJ.