Drug General Information (ID: DDIIPXD25B)
  Drug Name Urea Drug Info Lithium carbonate Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Topical Emollients Antimanic Agents
  Structure

 Mechanism of Urea-Lithium carbonate Interaction (Severity Level: Minor)
     Increased renal excretion (Unspecific) Click to Show/Hide Mechanism Graph
      Drug Name Urea Lithium carbonate
      Mechanism Increase the renal excretion of lithium Lithium carbonate
      Key Mechanism Factor 1
Factor Name Pharmacokinetics
Factor Description Alters the excretion of the drug, resulting in changes in the plasma concentration of the drug and affecting the pharmacological effects.
      Mechanism Description
  • Increased renal excretion of Lithium carbonate caused by Urea 

References
1 Product Information. Fycompa (perampanel). Eisai Inc, Teaneck, NJ.
2 Warrington SJ, Ankier SI, Turner P "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology 15 (1986): 31-7. [PMID: 3725002]
3 Thomsen K, Schou M "Renal lithium excretion in man." Am J Psychol 215 (1968): 823-7