Drug General Information (ID: DDII0B9OCW)
Drug Name			Levothyroxine		Drug Info		Epinephrine		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Antithyroid Agents				Vasoconstrictor Agents
Structure

Mechanism of Levothyroxine-Epinephrine Interaction (Severity Level: Moderate)
Potentiated the pharmacological effects (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Levothyroxine				Epinephrine
Mechanism		Potentiate the pharmacologic effects of sympathomimetic amine				Sympathomimetic amine
Key Mechanism Factor 1
		Factor Name		Pharmacodynamics
		Factor Description		Enhanced pharmacological effects leading to increased adverse reactions.
Mechanism Description		Potentiate the pharmacologic effects by the combination of Levothyroxine and Epinephrine

Recommended Action
Management		Monitoring for increased sympathomimetic effects and cardiac function may be advisable.

References
1	Product Information. Armour thyroid (thyroid desiccated). Forest Pharmaceuticals, St. Louis, MO.
2	Product Information. Synthroid (levothyroxine). Abbott Pharmaceutical, Abbott Park, IL.
3	Agencia Espaola de Medicamentos y Productos Sanitarios Healthcare "Centro de informacion online de medicamentos de la AEMPS - CIMA."