Drug General Information (ID: DDIE6IT7B8)
Drug Name			Theophylline		Drug Info		Felodipine		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Bronchodilators				Antihypertensive Agents
Structure

Mechanism of Theophylline-Felodipine Interaction (Severity Level: Minor)
Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Theophylline				Felodipine
Mechanism		Theophylline				Decrease absorption of theophylline
Key Mechanism Factor 1
		Factor Name		Pharmacokinetic
		Factor Description		Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Altered absorption of Theophylline caused by Felodipine

References
1	Bratel T, Billing B, Dahlqvist R "Felodipine reduces the absorption of theophylline in man." Eur J Clin Pharmacol 36 (1989): 481-5. [PMID: 2753066]
2	Upton RA "Pharmacokinetic interactions between theophylline and other medication (Part II)." Clin Pharmacokinet 20 (1991): 135-50. [PMID: 1709398]