Drug General Information (ID: DDIE50JWBL)
  Drug Name Cholestyramine Drug Info Iopanoic acid Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Bile Acid Sequestrants Diagnostic Agents
  Structure

 Mechanism of Cholestyramine-Iopanoic acid Interaction (Severity Level: Minor)
     Complex formation Click to Show/Hide Mechanism Graph
Could Not Find 2D Structure
      Drug Name Cholestyramine Iopanoic acid
      Mechanism Anion exchange resin/polymer Binds to anion exchange resin/polymer
      Key Mechanism Factor 1
Factor Name Chelation
Factor Description Chelation is a direct drug interaction that usually involves the formation of dimers or trimers, resulting in larger complexes and poorer absorption.
      Mechanism Description
  • Decreased absorption of Iopanoic acid due to formation of complexes caused by Cholestyramine 

References
1 Nelson JA "Effect of cholestyramine on telepaque oral cholecystography." Am J Roentgenol Radium Ther Nucl Med 122 (1974): 333-4. [PMID: 4418480]