Drug General Information (ID: DDIBQMWNP4)
Drug Name			Glucagon		Drug Info		Indomethacin		Drug Info
Drug Type		Hormones				Small molecule
Therapeutic Class		Hormone Modulators/Antidiabetic Agents				Antiinflammatory Agents
Structure

Mechanism of Glucagon-Indomethacin Interaction (Severity Level: Moderate)
Increased metabolism (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Glucagon				Indomethacin
Mechanism		Glucarpidase recombinant enzyme				Glucarpidase substrate
Key Mechanism Factor 1
		Factor Name		Pharmacokinetics
		Factor Description		Alters the metabolism of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
Mechanism Description		Increased metabolism of Indomethacin caused by Glucagon

Recommended Action
Management		Caution is recommended if glucagon must be administered to patients on indomethacin therapy.

References
1	Agencia Espaola de Medicamentos y Productos Sanitarios Healthcare "Centro de informacion online de medicamentos de la AEMPS - CIMA.".
2	Product Information. Indocin (indomethacin). Merck &amp Co, Inc, West Point, PA.