Drug General Information (ID: DDIBLOSK2X)
Drug Name			Saquinavir		Drug Info		Fosamprenavir		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Anti-Hiv Agents				Anti-Hiv Agents
Structure

Mechanism of Saquinavir-Fosamprenavir Interaction (Severity Level: Minor)
Attenuated pharmacological effects (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Saquinavir				Fosamprenavir
Mechanism		Decrease the therapeutic effects of fosamprenavir				Saquinavir
Key Mechanism Factor 1
		Factor Name		Pharmacodynamics
		Factor Description		Reduced pharmacological effects leading to insufficient efficacy and/or treatment failure.
Mechanism Description		Attenuated pharmacological effects of  Saquinavir when combined with Fosamprenavir

References
1	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2	Product Information. Agenerase (amprenavir). Glaxo Wellcome, Research Triangle Pk, NC.
3	Product Information. Lexiva (fosamprenavir). GlaxoSmithKline, Research Triangle Park, NC.