Drug General Information (ID: DDIA7ZXGYW)
Drug Name			Insulin human (regular)		Drug Info		Diflorasone (topical)		Drug Info
Drug Type		Hormones				Small molecule
Therapeutic Class		Insulin/Antidiabetic Agents				Antiinflammatory Agents
Structure

Mechanism of Insulin human (regular)-Diflorasone (topical) Interaction (Severity Level: Minor)
Antagonize the effect of antidiabetic agents Click to Show/Hide Mechanism Graph
Drug Name		Insulin human (regular)				Diflorasone (topical)
Mechanism 1		Antidiabetic agent				Hyperglycemia
Key Mechanism Factor 1
		Factor Name		Antidiabetic agents
		Factor Description		The hypoglycemic effect of antidiabetes may be reduced, leading to higher blood glucose, increased blood glucose fluctuations, and the possibility of hyperglycemic complications
Mechanism Description		Antagonize the effect of Insulin human (regular) when combined with Diflorasone (topical)
Mechanism 2		Antidiabetic agent				Hyperglycemic effects
Key Mechanism Factor 2
		Factor Name		Antidiabetic agents
		Factor Description		The hypoglycemic effect of antidiabetes may be reduced, leading to higher blood glucose, increased blood glucose fluctuations, and the possibility of hyperglycemic complications
Mechanism Description		Antagonize the effect of Insulin human (regular) when combined with Diflorasone (topical)

References
1	Seale JP, Compton MR "Side-effects of corticosteroid agents." Med J Aust 144 (1986): 139-42. [PMID: 3511355]
2	Product Information. Psorcon (diflorasone topical). Rhone-Poulenc Rorer, Collegeville, PA.
3	Pace WE "Topical corticosteroids." Can Med Assoc J 108 (1973): 11 passim. [PMID: 4682644]