Details of Drug

Details of Drug

 Drug General Information (ID: D1773)
  Drug Name
Diflorasone (topical)
  Drug Type Small molecule
  Drug Synonymous
Diflorasona; Diflorasonum; Maxiflor; Murode; U 34865; Diflorasona [INN-Spanish]; Diflorasone (INN); Diflorasone [INN:BAN]; Diflorasonum [INN-Latin]; Murode (TN); (6S,8S,9R,10S,11S,13S,14S,16S,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one; (6alpha,11beta,16beta)-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 6a,9a-difluoro-16b-methylprednisolone; 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
    Click to Show/Hide
  Disease Class ED90: Rosacea
  Therapeutic Class Antiinflammatory Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C22H28F2O5
  InChI 1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13-,14-,16-,17-,19-,20-,21-,22-/m0/s1
  InChIKey WXURHACBFYSXBI-XHIJKXOTSA-N
  Canonical SMILES CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C)F
  External Link
Pubchem ID 71415
CAS Number CAS 2557-49-5
CHEBI ID CHEBI:59750
TTD ID D0G7KJ

Drug-Drug Interaction Network
  Sunburst Graph
AM007  Pharmacodynamic antagonistic effects
BM086  Antagonize the effect of antidiabetic agents
BM089  Antagonize the effect of antihypertensive agents
  Relation Graph
 Full list of drugs interacting with Diflorasone (topical)
      Pharmacodynamic antagonistic effects
   Antagonize the effect of antidiabetic agents Drug Num:  10
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0811
 
Insulin glargine
 
C267H404N72O78S6
 
118984454 
Minor    Inter Info   
[1], [2], [3]
D0813
 
Insulin human
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[1], [2], [3]
D0814
 
Insulin human (inhalation, rapid acting)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[1], [2], [3]
D0815
 
Insulin human (isophane)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[1], [2], [3]
D0816
 
Insulin human (regular)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[1], [2], [3]
D0817
 
Insulin human (zinc extended)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[1], [2], [3]
D0818
 
Insulin human (zinc)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[1], [2], [3]
D0819
 
Insulin lispro
 
C257H389N65O77S6
 
16132438 
Minor    Inter Info   
[1], [2], [3]
D0820
 
Insulin lispro (protamine)
 
C257H389N65O77S6
 
16132438 
Minor    Inter Info   
[1], [2], [3]
D1652
 
Troglitazone
 
C24H27NO5S
 
5591 
Minor    Inter Info   
[1], [2], [3]
   Antagonize the effect of antihypertensive agents Drug Num:  32
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0009
 
Acarbose
 
C25H43NO18
 
41774 
Minor    Inter Info   
[1], [2], [3]
D0013
 
Acetohexamide
 
C15H20N2O4S
 
1989 
Minor    Inter Info   
[1], [2], [3]
D0029
 
Albiglutide
 
C148H224N40O45
 
145994868 
Minor    Inter Info   
[1], [2], [3]
D0042
 
Alogliptin
 
C18H21N5O2
 
11450633 
Minor    Inter Info   
[1], [2], [3]
D0245
 
Canagliflozin
 
C24H25FO5S
 
24812758 
Minor    Inter Info   
[1], [2], [3]
D0325
 
Chlorpropamide
 
C10H13ClN2O3S
 
2727 
Minor    Inter Info   
[1], [2], [3]
D0418
 
Dapagliflozin
 
C21H25ClO6
 
9887712 
Minor    Inter Info   
[1], [2], [3]
D1779
 
Dulaglutide
 
NA
 
NA
Minor    Inter Info   
[1], [2], [3]
D0565
 
Empagliflozin
 
C23H27ClO7
 
11949646 
Minor    Inter Info   
[1], [2], [3]
D1782
 
Ertugliflozin
 
C22H25ClO7
 
44814423 
Minor    Inter Info   
[1], [2], [3]
D1784
 
Exenatide
 
C184H282N50O60S
 
45588096 
Minor    Inter Info   
[1], [2], [3]
D0728
 
Glipizide
 
C21H27N5O4S
 
3478 
Minor    Inter Info   
[1], [2], [3]
D0730
 
Glyburide
 
C23H28ClN3O5S
 
3488 
Minor    Inter Info   
[1], [2], [3]
D0807
 
Insulin aspart (aspart protamine)
 
C256H381N65O79S6
 
118984445 
Minor    Inter Info   
[1], [2], [3]
D0808
 
Insulin aspart (aspart)
 
C256H381N65O79S6
 
118984445 
Minor    Inter Info   
[1], [2], [3]
D0810
 
Insulin detemir
 
C267H402N64O76S6
 
16137271 
Minor    Inter Info   
[1], [2], [3]
D0812
 
Insulin glulisine
 
C258H384N64O78S6
 
16136701 
Minor    Inter Info   
[1], [2], [3]
D0930
 
Linagliptin
 
C25H28N8O2
 
10096344 
Minor    Inter Info   
[1], [2], [3]
D0936
 
Liraglutide
 
C172H265N43O51
 
16134956 
Minor    Inter Info   
[1], [2], [3]
D0941
 
Lixisenatide
 
C215H347N61O65S
 
90472060 
Minor    Inter Info   
[1], [2], [3]
D1015
 
Metformin
 
C4H11N5
 
4091 
Minor    Inter Info   
[1], [2], [3]
D1064
 
Miglitol
 
C8H17NO5
 
441314 
Minor    Inter Info   
[1], [2], [3]
D1112
 
Nateglinide
 
C19H27NO3
 
5311309 
Minor    Inter Info   
[1], [2], [3]
D1294
 
Pioglitazone
 
C19H20N2O3S
 
4829 
Minor    Inter Info   
[1], [2], [3]
D1326
 
Pramlintide
 
C171H267N51O53S2
 
70691388 
Minor    Inter Info   
[1], [2], [3]
D1392
 
Repaglinide
 
C27H36N2O4
 
65981 
Minor    Inter Info   
[1], [2], [3]
D1429
 
Rosiglitazone
 
C18H19N3O3S
 
77999 
Minor    Inter Info   
[1], [2], [3]
D1449
 
Saxagliptin
 
C18H25N3O2
 
11243969 
Minor    Inter Info   
[1], [2], [3]
D1887
 
Semaglutide
 
C187H291N45O59
 
56843331 
Minor    Inter Info   
[1], [2], [3]
D1477
 
Sitagliptin
 
C16H15F6N5O
 
4369359 
Minor    Inter Info   
[1], [2], [3]
D1601
 
Tolazamide
 
C14H21N3O3S
 
5503 
Minor    Inter Info   
[1], [2], [3]
D1603
 
Tolbutamide
 
C12H18N2O3S
 
5505 
Minor    Inter Info   
[1], [2], [3]
References
1 Seale JP, Compton MR "Side-effects of corticosteroid agents." Med J Aust 144 (1986): 139-42. [PMID: 3511355]
2 Product Information. Psorcon (diflorasone topical). Rhone-Poulenc Rorer, Collegeville, PA.
3 Pace WE "Topical corticosteroids." Can Med Assoc J 108 (1973): 11 passim. [PMID: 4682644]