Drug General Information (ID: DDI8FHD40S)
  Drug Name Ascorbic acid Drug Info Propranolol Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Vitamins Antianxiety Agents
  Structure

 Mechanism of Ascorbic acid-Propranolol Interaction (Severity Level: Minor)
     Altered absorption (Unspecific) Click to Show/Hide Mechanism Graph
      Drug Name Ascorbic acid Propranolol
      Mechanism Decrease the absorption of propranolol Propranolol
      Key Mechanism Factor 1
Factor Name Pharmacokinetic
Factor Description Alters the absorption of the drug, leading to changes in the plasma concentration of the drug and affecting the pharmacological effects.
      Mechanism Description
  • Altered absorption of Propranolol caused by Ascorbic acid 

References
1 Gonzalez JP, Valdivieso A, Calvo R, Rodriquezsasiain JM, Jimenez R, Aguirre C, Dusouich P "Influence of vitamin c on the absorption and first pass metabolism of propranolol." Eur J Clin Pharmacol 48 (1995): 295-7. [PMID: 7589058]