Drug General Information (ID: DDI6TNC2GJ)
  Drug Name Trospium Drug Info Acetaminophen Drug Info
  Drug Type Small molecule Small molecule
  Therapeutic Class Parasympatholytics Analgesics
  Structure

 Mechanism of Trospium-Acetaminophen Interaction (Severity Level: Minor)
     Altered gastrointestinal dynamics Click to Show/Hide Mechanism Graph
Could Not Find 2D Structure
      Drug Name Trospium Acetaminophen
      Mechanism Delayed gastric emptying Absorption affected by delayed gastric emptying
      Key Mechanism Factor 1
Factor Name Gastrointestinal Motility
Factor Description Gastrointestinal motility is an important factor in determining the absorption of orally administered drugs, and it controls the residence time of the drug in the digestive tract.
      Mechanism Description
  • Altered absorption of Acetaminophen due to GI dynamics variation caused by Trospium 

References
1 Clark JM, Seager SJ "Gastric emptying following premedication with glycopyrrolate or atropine." Br J Anaesth 55 (1983): 1195-9. [PMID: 6652009]
2 Nimmo J, Heading RC, Tothill P, Prescott LF "Pharmacological modification of gastric emptying: effects of propantheline and metoclopramide on paracetamol absorption." Br Med J 1 (1973): 587-9. [PMID: 4694406]
3 Product Information. Transderm Scop (scopolamine). Ciba Self-Medication Inc, Woodbridge, NJ.