Drug General Information (ID: DDI6QZT4LK)
Drug Name			Tasimelteon		Drug Info		Levobetaxolol (ophthalmic)		Drug Info
Drug Type		Small molecule				Small molecule
Therapeutic Class		Anxiolytics/Sedatives/Hypnotics				Cardiotonic Agents
Structure

Mechanism of Tasimelteon-Levobetaxolol (ophthalmic) Interaction (Severity Level: Moderate)
Attenuated pharmacological effects (Unspecific) Click to Show/Hide Mechanism Graph
Drug Name		Tasimelteon				Levobetaxolol (ophthalmic)
Mechanism		Tasimelteon				Reduce therapeutic efficacy of tasimelteon
Key Mechanism Factor 1
		Factor Name		Pharmacodynamics
		Factor Description		Reduced pharmacological effects leading to insufficient efficacy and/or treatment failure.
Mechanism Description		Attenuated pharmacological effects of  Tasimelteon when combined with Levobetaxolol (ophthalmic)

Recommended Action
Management		Product labeling for tasimelteon suggests avoiding the nighttime administration of beta-blockers.

References
1	Product Information. Hetlioz (tasimelteon). Vanda Pharmaceuticals Inc, Rockville, MD.