Drug General Information (ID: DDI5J4FU0T)
Drug Name			Polythiazide		Drug Info		Garlic		Drug Info
Drug Type		Small molecule				Natural product
Therapeutic Class		Antihypertensive Agents				Herbal Products

Mechanism of Polythiazide-Garlic Interaction (Severity Level: Minor)
Additive hypotensive effects Click to Show/Hide Mechanism Graph
Drug Name		Polythiazide				Garlic
Mechanism 1		Antihypertensive agent				Antihypertensive agent
Key Mechanism Factor 1
		Factor Name		Hypotensive effects
		Factor Description		Hypotension is a blood pressure reading below the prescribed limit (90/60 mmHg). Symptoms of hypotension may include: blurred or faded vision , dizziness or light-headedness, fainting , fatigue , difficulty concentrating, nausea.
Mechanism Description		Additive hypotensive effects by the combination of Polythiazide and Garlic
Mechanism 2		Antihypertensive agent				Hypotensive effects
Key Mechanism Factor 2
		Factor Name		Hypotensive effects
		Factor Description		Hypotension is a blood pressure reading below the prescribed limit (90/60 mmHg). Symptoms of hypotension may include: blurred or faded vision , dizziness or light-headedness, fainting , fatigue , difficulty concentrating, nausea.
Mechanism Description		Additive hypotensive effects by the combination of Polythiazide and Garlic

References
1	Tattelman E "Health effects of garlic." Am Fam Physician 72 (2005): 103-6
2	Richard CL, Jurgens TM "Effects of natural health products on blood pressure." Ann Pharmacother 39 (2005): 712-20