Details of Drug-Drug Interaction
| Drug General Information (ID: DDI2BX9RY0) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Drug Name | Salicylic acid (sodium) | Drug Info | Gatifloxacin | Drug Info | |||||
| Drug Type | Small molecule | Small molecule | |||||||
| Therapeutic Class | Antiinflammatory Agents | Antiinfective Agents | |||||||
| Structure | |||||||||
| Mechanism of Salicylic acid (sodium)-Gatifloxacin Interaction (Severity Level: Moderate) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Additive CNS stimulant effects Click to Show/Hide Mechanism Graph | |||||||||
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| Drug Name | Salicylic acid (sodium) | Gatifloxacin | |||||||
| Mechanism | CNS stimulant effects | CNS stimulant effects | |||||||
| Key Mechanism Factor 1 | |||||||||
| Factor Name | CNS stimulant effects | ||||||||
| Factor Description | CNS stimulants are drugs that stimulate the brain and can speed up mental and physical processes. Excessive CNS stimulation may lead to decreased appetite, increased heart rate, increased blood pressure, increased body temperature, convulsions, and seizures. | ||||||||
| Mechanism Description |
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| Recommended Action | |||||||||
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| Management | Clinical monitoring for signs of CNS stimulation such as tremors, involuntary muscle movements, hallucinations, or seizures is recommended if fluoroquinolone antibiotics are prescribed in combination with NSAIDs. | ||||||||