Drug General Information (ID: DDI209F1SE)
Drug Name			Glyburide		Drug Info		Garlic		Drug Info
Drug Type		Small molecule				Natural product
Therapeutic Class		Antidiabetic Agents				Herbal Products

Mechanism of Glyburide-Garlic Interaction (Severity Level: Minor)
Increased risk of hypoglycemia Click to Show/Hide Mechanism Graph
Drug Name		Glyburide				Garlic
Mechanism		Antidiabetic agent				Increase the risk of hypoglycemia combined with antidiabetic agent
Key Mechanism Factor 1
		Factor Name		Hypoglycemia
		Factor Description		Hypoglycemia is a condition in which your blood sugar (glucose) level is below the standard range. It causes irregular or rapid heartbeat, pale skin, numbness of the lips, tongue or cheeks, and sweating.
Mechanism Description		Increased risk of hypoglycemia by the combination of Glyburide and Garlic

References
1	Izzo AA, Ernst E "Interactions between herbal medicines and prescribed drugs: a systematic review." Drugs 61 (2001): 2163-75. [PMID: 11772128]
2	Aslam M, Stockley IH "Interaction between curry ingredient (karela) and drug (chlorpropamide)." Lancet I (1979): 607
3	Semaan N "Integration of complementary disciplines into the oncology clinic - Part III. Herbal medicine - Drug interactions: The role of the pharmacist." Curr Prob Cancer 24 (2000): 213-22