Details of Drug

Details of Drug

 Drug General Information (ID: D1915)
  Drug Name
Tyropanoic acid
  Drug Type Small molecule
  Drug Synonymous
Tyropanoic acid|TYROPANIC ACID|tyropanoate|27293-82-9|2-[3-(BUTYRYLAMINO)-2,4,6-TRIIODOBENZYL]BUTYRIC ACID|2-[[3-(butanoylamino)-2,4,6-triiodophenyl]methyl]butanoic acid|Bilopac|Bilopaque|Lumopaque|Tyropaque|2-(3-Butyramido-2,4,6-triiodobenzyl)butanoic acid|Tyropanoic acid sodium salt|Acidum tyropanoicum|NSC107434|WIN 8851-2|7246-21-1|2-(3-(Butyrylamino)-2,4,6-triiodobenzyl)butyric acid|EINECS 248-389-8|starbld0000838|Tyropanoate sodium(USAN|Sodium Tyropanoate (USAN)|SCHEMBL2788021|CHEMBL1201261|DTXSID5048269|CHEBI:135862|DB09340|Q6587055|2-(3-(Butyrylamino)-2,4,6-triiodobenzyl)butanoic acid|Hydrocinnamic acid, 3-butyramido-.alpha.-ethyl-2,4,6-triiodo-|Sodium 3-butyramido-.alpha.-ethyl-2,4,6-triiodohydrocinnamate|2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methyl]butanoic acid|Benzenepropanoic acid, alpha-ethyl-2,4,6-triiodo-3-((1-oxobutyl)amino)-|Hydrocinnamic acid, 3-butyramido-.alpha.-ethyl-2,4,6-triiodo-, sodium salt|Hydrocinnamic acid, 3-butyramido-.alpha.-ethyl-2,4, 6-triiodo-, monosodium salt|Benzenepropanoic acid, .alpha.-ethyl-2,4, {6-triiodo-3-[(1-oxobutyl)amino]-,} monosodium salt
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  Therapeutic Class Diagnostic Radiopharmaceuticals
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C15H18I3NO3
  InChI InChI=1S/C15H18I3NO3/c1-3-5-12(20)19-14-11(17)7-10(16)9(13(14)18)6-8(4-2)15(21)22/h7-8H,3-6H2,1-2H3,(H,19,20)(H,21,22)
  InChIKey YMOXVLQZFAUUKI-UHFFFAOYSA-N
  Canonical SMILES CCCC(=O)NC1=C(C=C(C(=C1I)CC(CC)C(=O)O)I)I
  External Link
Pubchem ID 5611
INTEDE ID DR1654

Drug-Drug Interaction Network
  Sunburst Graph
AM001  Affected gastrointestinal absorption
AM006  Pharmacodynamic additive effects
BM003  Complex formation
BM048  Increased risk of angioedema/anaphylactoid reactions
BM072  Increased risk of nephrotoxicity
  Relation Graph
 Full list of drugs interacting with Tyropanoic acid
      Affected gastrointestinal absorption
   Complex formation Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0329
 
Cholestyramine
 
C27H47ClN2
 
137699107 
Minor    Inter Info   
[6]
      Pharmacodynamic additive effects
   Increased risk of angioedema/anaphylactoid reactions Drug Num:  17
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0010
 
Acebutolol
 
C18H28N2O4
 
1978 
Moderate    Inter Info   
[1], [2], [3]
D0117
 
Atenolol
 
C14H22N2O3
 
2249 
Moderate    Inter Info   
[1], [2], [3]
D0173
 
Betaxolol
 
C18H29NO3
 
2369 
Moderate    Inter Info   
[1], [2], [3]
D0174
 
Betaxolol (ophthalmic)
 
C18H29NO3
 
2369 
Moderate    Inter Info   
[1], [2], [3]
D0188
 
Bisoprolol
 
C18H31NO4
 
2405 
Moderate    Inter Info   
[1], [2], [3]
D0266
 
Carteolol (ophthalmic)
 
C16H24N2O3
 
2583 
Moderate    Inter Info   
[1], [2], [3]
D0267
 
Carvedilol
 
C24H26N2O4
 
2585 
Moderate    Inter Info   
[1], [2], [3]
D0602
 
Esmolol
 
C16H25NO4
 
59768 
Moderate    Inter Info   
[1], [2], [3]
D0884
 
Labetalol
 
C19H24N2O3
 
3869 
Moderate    Inter Info   
[1], [2], [3]
D0915
 
Levobunolol (ophthalmic)
 
C17H25NO3
 
39468 
Moderate    Inter Info   
[1], [2], [3]
D1045
 
Metipranolol (ophthalmic)
 
C17H27NO4
 
31477 
Moderate    Inter Info   
[1], [2], [3]
D1049
 
Metoprolol
 
C15H25NO3
 
4171 
Moderate    Inter Info   
[1], [2], [3]
D1098
 
Nadolol
 
C17H27NO4
 
39147 
Moderate    Inter Info   
[1], [2], [3]
D1114
 
Nebivolol
 
C22H25F2NO4
 
71301 
Moderate    Inter Info   
[1], [2], [3]
D1498
 
Sotalol
 
C12H20N2O3S
 
5253 
Moderate    Inter Info   
[1], [2], [3]
D1585
 
Timolol
 
C13H24N4O3S
 
33624 
Moderate    Inter Info   
[1], [2], [3]
D1586
 
Timolol (ophthalmic)
 
C13H24N4O3S
 
33624 
Moderate    Inter Info   
[1], [2], [3]
   Increased risk of nephrotoxicity Drug Num:  13
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0472
 
Diatrizoate
 
C11H9I3N2O4
 
2140 
Moderate    Inter Info   
[4], [2], [5]
D1791
 
Gadobenic acid
 
C22H28GdN3O11
 
9852779 
Moderate    Inter Info   
[4], [2], [5]
D1792
 
Gadobutrol
 
C18H31GdN4O9
 
6102852 
Moderate    Inter Info   
[4], [2], [5]
D1794
 
Gadofosveset trisodium
 
C33H38GdN3Na3O14P
 
73049652 
Moderate    Inter Info   
[4], [2], [5]
D1795
 
Gadopentetic acid
 
C14H20GdN3O10
 
6857474 
Moderate    Inter Info   
[4], [2], [5]
D0833
 
Iohexol
 
C19H26I3N3O9
 
3730 
Moderate    Inter Info   
[4], [2], [5]
D0834
 
Iopamidol
 
C17H22I3N3O8
 
65492 
Moderate    Inter Info   
[4], [2], [5]
D0836
 
Iopromide
 
C18H24I3N3O8
 
3736 
Moderate    Inter Info   
[4], [2], [5]
D0837
 
Iothalamic acid
 
C11H9I3N2O4
 
3737 
Moderate    Inter Info   
[4], [2], [5]
D0838
 
Ioversol
 
C18H24I3N3O9
 
3741 
Moderate    Inter Info   
[4], [2], [5]
D0839
 
Ioxilan
 
C18H24I3N3O8
 
3743 
Moderate    Inter Info   
[4], [2], [5]
D1254
 
Perflutren
 
C3F8
 
6432 
Moderate    Inter Info   
[4], [2], [5]
D0652
 
Ferumoxides
 
Fe3O4
 
6432052 
Moderate    Inter Info   
[4], [2], [5]
References
1 Product Information. Osmovist 240 (iotrolan). Berlex Canada Inc, Lachine, QC.
2 Product Information. Visipaque (iodixanol). Nycomed Inc, Princeton, NJ.
3 Costa N "Understanding contrast media." J Infus Nurs 27 (2004): 302-12. [PMID: 15385894]
4 Product Information. Ultravist (iopromide). Berlex, Richmond, CA.
5 Product Information. Omniscan (gadodiamide). Novation, Irving, TX.
6 Nelson JA "Effect of cholestyramine on telepaque oral cholecystography." Am J Roentgenol Radium Ther Nucl Med 122 (1974): 333-4. [PMID: 4418480]