Details of Drug

Drug General Information (ID: D1893)
Drug Name	Sorbitol
Drug Type	Small molecule
Drug Synonymous	D-Sorbitol; sorbitol; D-Glucitol; 50-70-4; glucitol; L-Gulitol; (-)-Sorbitol; Glucarine; Sorbilande; Diakarmon; Sorbostyl; Multitol; Nivitin; Karion; Esasorb; Neosorb; D-(-)-Sorbitol; Sorbol; Cholaxine; Sorbite; Sionit; Sionite; Siosan; Sionon; Karion instant; Sorbitol F; Sorbitol FP; Sorbex Rp; Sorbitol syrup C; Sorbex X; Sorbex R; Sorbex M; Sorbex S; Sionit K; D-Sorbol; Hexahydric alcohol; Sorbicolan; Sorvilande; Neosorb P 60; D-Sorbite; Foodol D 70; Neosorb 20/60DC; Neosorb 70/70; Neosorb 70/02; Neosorb P 20/60; d-Sorbit; Karion (carbohydrate) Click to Show/Hide
Disease Class	DD91: Irritable bowel syndrome
Therapeutic Class	Laxatives
Structure
Structure	3D Structure		2D Structure
Formula	C6H14O6
InChI	1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1
InChIKey	FBPFZTCFMRRESA-JGWLITMVSA-N
Canonical SMILES	C(C(C(C(C(CO)O)O)O)O)O
External Link
	Pubchem ID	5780
	CAS Number	CAS 50-70-4
	CHEBI ID	CHEBI:17924
	TTD ID	D09MXS
	INTEDE ID	DR1933

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM107 Attenuated pharmacological effects (Unspecific) BM109 Increased risk of other adverse reactions (Unspecific)
Relation Graph

Full list of drugs interacting with Sorbitol
Pharmacodynamic additive effects
	Increased risk of other adverse reactions (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1605		Tolevamer	C11H16O3S	58817179	Major		Inter Info	[1], [2], [3]
Pharmacodynamic antagonistic effects
	Attenuated pharmacological effects (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0889		Lamivudine	C8H11N3O3S	60825	Moderate		Inter Info	[4], [5], [6]

References
1	Product Information. Kayexalate (sodium polystyrene sulfonate). Sanofi Winthrop Pharmaceuticals, New York, NY.
2	Product Information. Mobic (meloxicam) Boehringer-Ingelheim, Ridgefield, CT.
3	Lillemoe KD, Romolo JL, Hamilton SR, Pennington LR, Burdick JF, Williams GM "Intestinal necrosis due to sodium polystyrene (Kayexalate) in sorbitol enemas: clinical and experimental support for the hypothesis." Surgery 101 (1987): 267-72. [PMID: 3824154]
4	Cerner Multum, Inc. "Australian Product Information.".
5	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
6	Adkison K, Wolstenholme A, Lou Y, et al. "Effect of Sorbitol on the Pharmacokinetic Profile of Lamivudine Oral Solution in Adults: An Open-label, Randomized Study." Clin Pharmacol Ther (2017):. [PMID: 29150845]