Details of Drug

Drug General Information (ID: D1885)
Drug Name		Saw palmetto
Drug Type		Natural product
Drug Synonymous		84604-15-9; Sabal serulata; Saw Palmetto (Serenoa repens) Extract; Saw Palmetto (Serenoa repens) Extract; Prosta Urgenin; Sabal serulata (Michx.) Benth. et Hook. (Aracaceae); Extract of saw palmetto; Sabal serulata extract; Saw palmetto extract; Sabal serrulatum, ext.; EINECS 283-292-4; Saw Palmetto (Serenoa repens) Extract [berry]; Saw Palmetto [berry]; Saw Palmetto Click to Show/Hide
Therapeutic Class		Herbal Products

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM007 Pharmacodynamic antagonistic effects BM094 Antagonize the effect of estrogen
Relation Graph

Full list of drugs interacting with Saw palmetto
Pharmacodynamic antagonistic effects
	Antagonize the effect of estrogen					Drug Num: 13
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0387		Conjugated estrogens	C18H21NaO5S	45357473	Minor		Inter Info	[1], [2], [3]
D0388		Conjugated estrogens (topical)	C18H21NaO5S	45357473	Minor		Inter Info	[1], [2], [3]
D0484		Dienestrol (topical)	C18H18O2	667476	Minor		Inter Info	[1], [2], [3]
D0487		Diethylstilbestrol	C18H20O2	448537	Minor		Inter Info	[1], [2], [3]
D0605		Esterified estrogens	NA	NA	Minor		Inter Info	[1], [2], [3]
D0606		Estradiol	C18H24O2	5757	Minor		Inter Info	[1], [2], [3]
D0607		Estradiol (topical)	C18H24O2	5757	Minor		Inter Info	[1], [2], [3]
D0609		Estrone	C18H22O2	5870	Minor		Inter Info	[1], [2], [3]
D0610		Estrone sulfate	C18H22O5S	3001028	Minor		Inter Info	[1], [2], [3]
D0611		Estrone sulfate (topical)	C18H22O5S	3001028	Minor		Inter Info	[1], [2], [3]
D0619		Ethinylestradiol	C20H24O2	5991	Minor		Inter Info	[1], [2], [3]
D1011		Mestranol	C21H26O2	6291	Minor		Inter Info	[1], [2], [3]
D1370		Quinestrol	C25H32O2	9046	Minor		Inter Info	[1], [2], [3]

References
1	Miller LG "Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions." Arch Intern Med 158 (1998): 2200-11. [PMID: 9818800]
2	Schubert W, Eriksson U, Edgar B, Cullberg G, Hedner T "Flavonoids in grapefruit juice inhibit the in vitro hepatic metabolism of 17B-estradiol." Eur J Drug Metab Pharmacokinet 20 (1995): 219-24. [PMID: 8751044]
3	Weber A, Jager R, Borner A, et al. "Can grapefruit juice influence ethinyl estradiol bioavailability?" Contraception 53 (1996): 41-7. [PMID: 8631189]