Details of Drug

Drug General Information (ID: D1868)
Drug Name	Pralidoxime
Drug Type	Small molecule
Drug Synonymous	pralidoxime\|Pralidoximum\|2-PAM\|UNII-P7MU9UTP52\|PRALIDOXIME CHLORIDE\|P7MU9UTP52\|6735-59-7\|2-[(E)-(hydroxyimino)methyl]-1-methylpyridinium\|Pralidoxime ion\|1-Methyl-2-pyridinium aldoxime\|Pralidoxime cation\|Pyridinium, 2-((hydroxyimino)methyl)-1-methyl-, iodide\|NSC7760\|NSC164614\|Pralidoxime [INN:BAN]\|94-63-3\|CHEBI:8354\|Pralidoxime (3)\|Pyridinium, 2-((hydroxyimino)methyl)-1-methyl-, chloride\|FP1\|EINECS 229-787-0\|Pralidoxime [VANDF]\|Pralidoxime [MART.]\|Pralidoxime [WHO-DD]\|Prestwick2_000943\|Prestwick3_000943\|Spectrum5_001138\|C07400\|BSPBio_000906\|BSPBio_003115\|SCHEMBL439968\|BPBio1_000998\|DTXSID1044144\|HSDB 8490\|BDBM234367\|STL371214\|AKOS005207264\|DB00733\|MCULE-9475708961\|IDI1_000770\|25615-00-3\|2-((Hydroxyimino)methyl)-1-methylpyridinium\|AB00513971\|AB00572627_09\|(2E)-1-methylpyridin-1-ium-2-carbaldehyde oxime\|(NE)-N-[(1-methylpyridin-1-ium-2-yl)methylidene]hydroxylamine Click to Show/Hide
Therapeutic Class	Antidotes
Structure
Structure	3D Structure		2D Structure
Formula	C7H9N2O+
InChI	InChI=1S/C7H8N2O/c1-9-5-3-2-4-7(9)6-8-10/h2-6H,1H3/p+1
InChIKey	JBKPUQTUERUYQE-UHFFFAOYSA-O
Canonical SMILES	C[N+]1=CC=CC=C1/C=N/O
External Link
External Link	Pubchem ID	135398747

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM033 Additive anticholinergic effects BM095 Antagonize the effect of neuromuscular blocking agents
Relation Graph

Full list of drugs interacting with Pralidoxime
Pharmacodynamic additive effects
	Additive anticholinergic effects					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0123		Atropine	C17H23NO3	174174	Minor		Inter Info	[1]
Pharmacodynamic antagonistic effects
	Antagonize the effect of neuromuscular blocking agents					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1080		Mivacurium	C58H80N2O14+2	5281042	Moderate		Inter Info	[1], [2]
D1510		Succinylcholine	C14H30N2O4+2	5314	Moderate		Inter Info	[1], [2]

References
1	Product Information. DuoDote (atropine-pralidoxime). Meridian Medical Technologies Inc, Columbia, MD.
2	Selden BS, Curry SC "Prolonged succinylcholine-induced paralysis in organophosphate insecticide poisoning." Ann Emerg Med 16 (1987): 215-7. [PMID: 2432808]