Details of Drug

Drug General Information (ID: D1822)
Drug Name	Iodide I-123
Drug Type	Small molecule
Drug Synonymous	Iodide ion I-123\|iodine-123(1-)\|UNII-98QPV8670C\|69239-56-1\|98QPV8670C\|I-123\|Iodide-123\|Iodide (123I(1-))\|Iodine 123\|Iodide I-123\|(~123~I)Iodide\|DTXSID40988959\|DB09420\|123I-\|Q3801335 Click to Show/Hide
Therapeutic Class	Diagnostic Radiopharmaceuticals
Structure
Structure	3D Structure		2D Structure
Formula	I-
InChI	InChI=1S/HI/h1H/p-1/i1-4
InChIKey	XMBWDFGMSWQBCA-AHCXROLUSA-M
Canonical SMILES	[123I-]
External Link
External Link	Pubchem ID	135300

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM003 Affected organization distribution AM007 Pharmacodynamic antagonistic effects BM014 Interference of cell/tissue uptake BM107 Attenuated pharmacological effects (Unspecific)
Relation Graph

Full list of drugs interacting with Iodide I-123
Affected organization distribution
	Interference of cell/tissue uptake					Drug Num: 134
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0017		Acetylsalicylic acid	C9H8O4	2244	Moderate		Inter Info	[1], [2], [3]
D0028		Albendazole	C12H15N3O2S	2082	Moderate		Inter Info	[1], [2], [3]
D0037		Alimemazine	C18H22N2S	5574	Moderate		Inter Info	[1], [2], [3]
D0045		Alprazolam	C17H13ClN4	2118	Moderate		Inter Info	[1], [2], [3]
D0066		Amiodarone	C25H29I2NO3	2157	Moderate		Inter Info	[1], [2], [3]
D0073		Amoxicillin	C16H19N3O5S	33613	Moderate		Inter Info	[1], [2], [3]
D0079		Ampicillin	C16H19N3O4S	6249	Moderate		Inter Info	[1], [2], [3]
D0087		Anisindione	C16H12O3	2197	Moderate		Inter Info	[1], [2], [3]
D0096		Apixaban	C25H25N5O4	10182969	Moderate		Inter Info	[1], [2], [3]
D0102		Ardeparin	C26H42N2O37S5	772	Moderate		Inter Info	[1], [2], [3]
D0104		Argatroban	C23H36N6O5S	92722	Moderate		Inter Info	[1], [2], [3]
D0108		Artemether	C16H26O5	68911	Moderate		Inter Info	[1], [2], [3]
D0115		Astemizole	C28H31FN4O	2247	Moderate		Inter Info	[1], [2], [3]
D0121		Atovaquone	C22H19ClO3	74989	Moderate		Inter Info	[1], [2], [3]
D0135		Azatadine	C20H22N2	19861	Moderate		Inter Info	[1], [2], [3]
D0141		Bacampicillin	C21H27N3O7S	441397	Moderate		Inter Info	[1], [2], [3]
D0167		Benzylpenicillin	C16H18N2O4S	5904	Moderate		Inter Info	[1], [2], [3]
D0168		Benzylpenicillin (potassium)	C16H18N2O4S	5904	Moderate		Inter Info	[1], [2], [3]
D0169		Benzylpenicillin (sodium)	C16H18N2O4S	5904	Moderate		Inter Info	[1], [2], [3]
D0172		Betamethasone	C22H29FO5	9782	Moderate		Inter Info	[1], [2], [3]
D0189		Bivalirudin	C98H138N24O33	16129704	Moderate		Inter Info	[1], [2], [3]
D0214		Brompheniramine	C16H19BrN2	6834	Moderate		Inter Info	[1], [2], [3]
D0215		Budesonide	C25H34O6	5281004	Moderate		Inter Info	[1], [2], [3]
D0257		Carbenicillin	C17H18N2O6S	20824	Moderate		Inter Info	[1], [2], [3]
D0259		Carbinoxamine	C16H19ClN2O	2564	Moderate		Inter Info	[1], [2], [3]
D0305		Cetirizine	C21H25ClN2O3	2678	Moderate		Inter Info	[1], [2], [3]
D0316		Chlorcyclizine	C18H21ClN2	2710	Moderate		Inter Info	[1], [2], [3]
D0317		Chlordiazepoxide	C16H14ClN3O	2712	Moderate		Inter Info	[1], [2], [3]
D0320		Chloroquine	C18H26ClN3	2719	Moderate		Inter Info	[1], [2], [3]
D0323		Chlorpheniramine	C16H19ClN2	2725	Moderate		Inter Info	[1], [2], [3]
D0351		Clemastine	C21H26ClNO	26987	Moderate		Inter Info	[1], [2], [3]
D0356		Clobazam	C16H13ClN2O2	2789	Moderate		Inter Info	[1], [2], [3]
D0362		Clonazepam	C15H10ClN3O3	2802	Moderate		Inter Info	[1], [2], [3]
D0365		Clorazepic acid	C16H11ClN2O3	2809	Moderate		Inter Info	[1], [2], [3]
D0369		Cloxacillin	C19H18ClN3O5S	6098	Moderate		Inter Info	[1], [2], [3]
D0403		Cyproheptadine	C21H21N	2913	Moderate		Inter Info	[1], [2], [3]
D0414		Dalteparin	C26H42N2O37S5	772	Moderate		Inter Info	[1], [2], [3]
D0415		Danaparoid	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0419		Dapsone	C12H12N2O2S	2955	Moderate		Inter Info	[1], [2], [3]
D0448		Desloratadine	C19H19ClN2	124087	Moderate		Inter Info	[1], [2], [3]
D0453		Dexamethasone	C22H29FO5	5743	Moderate		Inter Info	[1], [2], [3]
D0456		Dexbrompheniramine	C16H19BrN2	16960	Moderate		Inter Info	[1], [2], [3]
D0472		Diatrizoate	C11H9I3N2O4	2140	Moderate		Inter Info	[4], [3], [5]
D0473		Diazepam	C16H13ClN2O	3016	Moderate		Inter Info	[1], [2], [3]
D0480		Dicloxacillin	C19H17Cl2N3O5S	18381	Moderate		Inter Info	[1], [2], [3]
D0481		Dicoumarol	C19H12O6	54676038	Moderate		Inter Info	[1], [2], [3]
D0489		Diflunisal	C13H8F2O3	3059	Moderate		Inter Info	[1], [2], [3]
D0496		Diiodohydroxyquinoline	C9H5I2NO	3728	Moderate		Inter Info	[4], [3], [5]
D0502		Diphenhydramine	C17H21NO	3100	Moderate		Inter Info	[1], [2], [3]
D0537		Drotrecogin alfa	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0551		Edoxaban	C24H30ClN7O4S	10280735	Moderate		Inter Info	[1], [2], [3]
D0574		Enoxaparin	C26H42N2O37S5	772	Moderate		Inter Info	[1], [2], [3]
D0604		Estazolam	C16H11ClN4	3261	Moderate		Inter Info	[1], [2], [3]
D1783		Ethiodized oil	NA	NA	Moderate		Inter Info	[4], [3], [5]
D0656		Fexofenadine	C32H39NO4	3348	Moderate		Inter Info	[1], [2], [3]
D0671		Fludrocortisone	C21H29FO5	31378	Moderate		Inter Info	[1], [2], [3]
D0679		Flurazepam	C21H23ClFN3O	3393	Moderate		Inter Info	[1], [2], [3]
D0690		Fondaparinux	C31H53N3O49S8	5282448	Moderate		Inter Info	[1], [2], [3]
D0748		Halazepam	C17H12ClF3N2O	31640	Moderate		Inter Info	[1], [2], [3]
D0749		Halofantrine	C26H30Cl2F3NO	37393	Moderate		Inter Info	[1], [2], [3]
D0753		Heparin	C26H42N2O37S5	772	Moderate		Inter Info	[1], [2], [3]
D0773		Hydrocortisone	C21H30O5	5754	Moderate		Inter Info	[1], [2], [3]
D0777		Hydroxocobalamin	C62H90CoN13O15P	70689311	Moderate		Inter Info	[1], [2], [3]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Moderate		Inter Info	[1], [2], [3]
D0781		Hydroxyzine	C21H27ClN2O2	3658	Moderate		Inter Info	[1], [2], [3]
D1823		Iodine	I2	807	Moderate		Inter Info	[4], [3], [5]
D1824		Iodine (topical)	I2	807	Moderate		Inter Info	[4], [3], [5]
D0831		Iodipamide	C20H14I6N2O6	3739	Moderate		Inter Info	[4], [3], [5]
D0832		Iodixanol	C35H44I6N6O15	3724	Moderate		Inter Info	[4], [3], [5]
D0833		Iohexol	C19H26I3N3O9	3730	Moderate		Inter Info	[4], [3], [5]
D0834		Iopamidol	C17H22I3N3O8	65492	Moderate		Inter Info	[4], [3], [5]
D0835		Iopodic acid	C12H13I3N2O2	5241	Moderate		Inter Info	[4], [3], [5]
D0836		Iopromide	C18H24I3N3O8	3736	Moderate		Inter Info	[4], [3], [5]
D0837		Iothalamic acid	C11H9I3N2O4	3737	Moderate		Inter Info	[4], [3], [5]
D0838		Ioversol	C18H24I3N3O9	3741	Moderate		Inter Info	[4], [3], [5]
D0839		Ioxilan	C18H24I3N3O8	3743	Moderate		Inter Info	[4], [3], [5]
D0870		Ivermectin	C48H74O14	6321424	Moderate		Inter Info	[1], [2], [3]
D0904		Lepirudin	C287H440N80O111S6	118856773	Moderate		Inter Info	[1], [2], [3]
D0917		Levocetirizine	C21H25ClN2O3	1549000	Moderate		Inter Info	[1], [2], [3]
D0950		Loratadine	C22H23ClN2O2	3957	Moderate		Inter Info	[1], [2], [3]
D0951		Lorazepam	C15H10Cl2N2O2	3958	Moderate		Inter Info	[1], [2], [3]
D0982		Mebendazole	C16H13N3O3	4030	Moderate		Inter Info	[1], [2], [3]
D0992		Mefloquine	C17H16F6N2O	4046	Moderate		Inter Info	[1], [2], [3]
D1006		Mepyramine	C17H23N3O	4992	Moderate		Inter Info	[1], [2], [3]
D1019		Methdilazine	C18H20N2S	14677	Moderate		Inter Info	[1], [2], [3]
D1021		Methimazole	C4H6N2S	1349907	Moderate		Inter Info	[1], [2], [3]
D1041		Methylprednisolone	C22H30O5	6741	Moderate		Inter Info	[1], [2], [3]
D1044		Meticillin	C17H20N2O6S	6087	Moderate		Inter Info	[1], [2], [3]
D1051		Metronidazole	C6H9N3O3	4173	Moderate		Inter Info	[1], [2], [3]
D1055		Mezlocillin	C21H25N5O8S2	656511	Moderate		Inter Info	[1], [2], [3]
D1060		Midazolam	C18H13ClFN3	4192	Moderate		Inter Info	[1], [2], [3]
D1099		Nafcillin	C21H22N2O5S	8982	Moderate		Inter Info	[1], [2], [3]
D1147		Nitroprusside	C5FeN6O	11953891	Moderate		Inter Info	[1], [2], [3]
D1192		Oxacillin	C19H19N3O5S	6196	Moderate		Inter Info	[1], [2], [3]
D1194		Oxamniquine	C14H21N3O3	4612	Moderate		Inter Info	[1], [2], [3]
D1197		Oxazepam	C15H11ClN2O2	4616	Moderate		Inter Info	[1], [2], [3]
D1226		Paricalcitol	C27H44O3	5281104	Moderate		Inter Info	[1], [2], [3]
D1228		Paromomycin	C23H45N5O14	165580	Moderate		Inter Info	[1], [2], [3]
D1246		Pentamidine	C19H24N4O2	4735	Moderate		Inter Info	[1], [2], [3]
D1264		Phenindamine	C19H19N	11291	Moderate		Inter Info	[1], [2], [3]
D1268		Phenoxymethylpenicillin	C16H18N2O5S	6869	Moderate		Inter Info	[1], [2], [3]
D1296		Piperacillin	C23H27N5O7S	43672	Moderate		Inter Info	[1], [2], [3]
D1297		Piperazine	C4H10N2	4837	Moderate		Inter Info	[1], [2], [3]
D1321		Potassium Iodide	IK	4875	Moderate		Inter Info	[4], [3], [5]
D1330		Praziquantel	C19H24N2O2	4891	Moderate		Inter Info	[1], [2], [3]
D1334		Prednisone	C21H26O5	5865	Moderate		Inter Info	[1], [2], [3]
D1339		Primaquine	C15H21N3O	4908	Moderate		Inter Info	[1], [2], [3]
D1350		Proguanil	C11H16ClN5	6178111	Moderate		Inter Info	[1], [2], [3]
D1352		Promethazine	C17H20N2S	4927	Moderate		Inter Info	[1], [2], [3]
D1359		Propylthiouracil	C7H10N2OS	657298	Moderate		Inter Info	[1], [2], [3]
D1366		Pyrimethamine	C12H13ClN4	4993	Moderate		Inter Info	[1], [2], [3]
D1367		Quazepam	C17H11ClF4N2S	4999	Moderate		Inter Info	[1], [2], [3]
D1372		Quinine	C20H24N2O2	3034034	Moderate		Inter Info	[1], [2], [3]
D1417		Rivaroxaban	C19H18ClN3O5S	9875401	Moderate		Inter Info	[1], [2], [3]
D1439		Salicylic acid (sodium)	C7H6O3	338	Moderate		Inter Info	[1], [2], [3]
D1442		Salsalate	C14H10O5	5161	Moderate		Inter Info	[1], [2], [3]
D1513		Sulfadiazine	C10H10N4O2S	5215	Moderate		Inter Info	[1], [2], [3]
D1514		Sulfadoxine	C12H14N4O4S	17134	Moderate		Inter Info	[1], [2], [3]
D1515		Sulfamethizole	C9H10N4O2S2	5328	Moderate		Inter Info	[1], [2], [3]
D1516		Sulfamethoxazole	C10H11N3O3S	5329	Moderate		Inter Info	[1], [2], [3]
D1517		Sulfasalazine	C18H14N4O5S	5339	Moderate		Inter Info	[1], [2], [3]
D1547		Temazepam	C16H13ClN2O2	5391	Moderate		Inter Info	[1], [2], [3]
D1555		Terfenadine	C32H41NO2	5405	Moderate		Inter Info	[1], [2], [3]
D1571		Thiabendazole	C10H7N3S	5430	Moderate		Inter Info	[1], [2], [3]
D1573		Thiopental	C11H18N2O2S	3000715	Moderate		Inter Info	[1], [2], [3]
D1580		Ticarcillin	C15H16N2O6S2	36921	Moderate		Inter Info	[1], [2], [3]
D1587		Tinidazole	C8H13N3O4S	5479	Moderate		Inter Info	[1], [2], [3]
D1588		Tinzaparin	C26H42N2O37S5	772	Moderate		Inter Info	[1], [2], [3]
D1603		Tolbutamide	C12H18N2O3S	5505	Moderate		Inter Info	[1], [2], [3]
D1628		Triamcinolone	C21H27FO6	31307	Moderate		Inter Info	[1], [2], [3]
D1632		Triazolam	C17H12Cl2N4	5556	Moderate		Inter Info	[1], [2], [3]
D1646		Trimetrexate	C19H23N5O3	5583	Moderate		Inter Info	[1], [2], [3]
D1650		Triprolidine	C19H22N2	5282443	Moderate		Inter Info	[1], [2], [3]
D1711		Warfarin	C19H16O4	54678486	Moderate		Inter Info	[1], [2], [3]
Pharmacodynamic antagonistic effects
	Attenuated pharmacological effects (Unspecific)					Drug Num: 14
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0020		Acrivastine	C22H24N2O2	5284514	Moderate		Inter Info	[1], [2], [3]
D0092		Antithrombin Alfa	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0093		Antithrombin III human	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0162		Benznidazole	C12H12N4O3	31593	Moderate		Inter Info	[1], [2], [3]
D0176		Betrixaban	C23H22ClN5O3	10275777	Moderate		Inter Info	[1], [2], [3]
D0331		Choline salicylate	C12H19NO4	54686350	Moderate		Inter Info	[1], [2], [3]
D0436		Deflazacort	C25H31NO6	189821	Moderate		Inter Info	[1], [2], [3]
D0447		Desirudin	C287H440N80O110S6	16129703	Moderate		Inter Info	[1], [2], [3]
D0940		Lithium carbonate	CLi2O3	11125	Moderate		Inter Info	[1], [2], [3]
D1272		Phenyl salicylate	C13H10O3	8361	Moderate		Inter Info	[1], [2], [3]
D1282		Phenyltoloxamine	C17H21NO	7077	Moderate		Inter Info	[1], [2], [3]
D1871		Pyrantel	C11H14N2S	708857	Moderate		Inter Info	[1], [2], [3]
D1452		Secnidazole	C7H11N3O3	71815	Moderate		Inter Info	[1], [2], [3]
D1892		Sodium iodide	INa	5238	Moderate		Inter Info	[4], [3], [5]

References
1	Product Information. Rexulti (brexpiprazole). Otsuka American Pharmaceuticals Inc, Rockville, MD.
2	Warrington SJ, Ankier SI, Turner P "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology 15 (1986): 31-7. [PMID: 3725002]
3	Product Information. Sodium Iodide I-123 (sodium iodide I-123). GE Healthcare, Princeton, NJ.
4	Cerner Multum, Inc. "Australian Product Information.".
5	Product Information. Visipaque (iodixanol). Nycomed Inc, Princeton, NJ.

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