Details of Drug

Details of Drug

 Drug General Information (ID: D1821)
  Drug Name
Iobenguane (I-123)
  Drug Type Small molecule
  Drug Synonymous
Iobenguane|m-Iodobenzylguanidine|80663-95-2|Metaiodobenzylguanidine|meta-Iodobenzylguanidine|3-Iodobenzylguanidine|2-[(3-iodophenyl)methyl]guanidine|UNII-35MRW7B4AD|MIBG|Guanidine, ((3-iodophenyl)methyl)-|139755-80-9|Guanidine,N-[(3-iodophenyl)methyl]-|1-(3-Iodobenzyl)guanidine|2-(3-Iodobenzyl)guanidine|35MRW7B4AD|(3-Iodobenzyl)guanidine|NCGC00015572-04|SR-01000075167|Prestwick-07A11|starbld0001019|Iobenguane (127-i)|meta-iodobenzyl guanidine|Prestwick0_000490|Prestwick1_000490|Prestwick2_000490|Prestwick3_000490|Lopac-I-9890|2-m-iodo-benzyl guanidine|CHEMBL818|Lopac0_000644|BSPBio_000359|SCHEMBL140591|SPBio_002280|BPBio1_000395|((3-iodophenyl)methyl)guanidine|DTXSID4048438|CHEBI:92769|1-[(3-iodophenyl)methyl]guanidine|ZINC1538318|CCG-204731|DB06704|SDCCGSBI-0050624.P002|NCGC00015572-01|NCGC00015572-02|NCGC00015572-03|NCGC00015572-06|NCGC00015572-09|NCGC00162211-01|DA-02654|Q3154058|SR-01000075167-1|BRD-K43860855-065-03-6
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  Therapeutic Class Diagnostic Radiopharmaceuticals
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C8H10IN3
  InChI InChI=1S/C8H10IN3/c9-7-3-1-2-6(4-7)5-12-8(10)11/h1-4H,5H2,(H4,10,11,12)
  InChIKey PDWUPXJEEYOOTR-UHFFFAOYSA-N
  Canonical SMILES C1=CC(=CC(=C1)I)CN=C(N)N
  External Link
Pubchem ID 60860

Drug-Drug Interaction Network
  Sunburst Graph
AM003  Affected organization distribution
BM014  Interference of cell/tissue uptake
  Relation Graph
 Full list of drugs interacting with Iobenguane (I-123)
      Affected organization distribution
   Interference of cell/tissue uptake Drug Num:  76
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0037
 
Alimemazine
 
C18H22N2S
 
5574 
Moderate    Inter Info   
[1], [2], [3]
D0068
 
Amitriptyline
 
C20H23N
 
2160 
Moderate    Inter Info   
[1], [2], [3]
D0072
 
Amoxapine
 
C17H16ClN3O
 
2170 
Moderate    Inter Info   
[1], [2], [3]
D0074
 
Amphetamine
 
C9H13N
 
3007 
Moderate    Inter Info   
[1], [2], [3]
D0165
 
Benzphetamine
 
C17H21N
 
5311017 
Moderate    Inter Info   
[1], [2], [3]
D0200
 
Bretylium
 
C11H17BrN+
 
2431 
Moderate    Inter Info   
[1], [2], [3]
D0220
 
Bupropion
 
C13H18ClNO
 
444 
Moderate    Inter Info   
[1], [2], [3]
D0324
 
Chlorpromazine
 
C17H19ClN2S
 
2726 
Moderate    Inter Info   
[1], [2], [3]
D0345
 
Citalopram
 
C20H21FN2O
 
2771 
Moderate    Inter Info   
[1], [2], [3]
D0361
 
Clomipramine
 
C19H23ClN2
 
2801 
Moderate    Inter Info   
[1], [2], [3]
D0378
 
Cocaine (topical)
 
C17H21NO4
 
446220 
Moderate    Inter Info   
[1], [2], [3]
D0444
 
Deserpidine
 
C32H38N2O8
 
8550 
Moderate    Inter Info   
[1], [2], [3]
D0446
 
Desipramine
 
C18H22N2
 
2995 
Moderate    Inter Info   
[1], [2], [3]
D0451
 
Desvenlafaxine
 
C16H25NO2
 
125017 
Moderate    Inter Info   
[1], [2], [3]
D0457
 
Dexfenfluramine
 
C12H16F3N
 
66265 
Moderate    Inter Info   
[1], [2], [3]
D0465
 
Dextroamphetamine
 
C9H13N
 
5826 
Moderate    Inter Info   
[1], [2], [3]
D0486
 
Diethylpropion
 
C13H19NO
 
7029 
Moderate    Inter Info   
[1], [2], [3]
D0517
 
Dopamine
 
C8H11NO2
 
681 
Moderate    Inter Info   
[1], [2], [3]
D0523
 
Doxapram
 
C24H30N2O2
 
3156 
Moderate    Inter Info   
[1], [2], [3]
D0525
 
Doxepin
 
C19H21NO
 
667477 
Moderate    Inter Info   
[1], [2], [3]
D0526
 
Doxepin (topical)
 
C19H21NO
 
667477 
Moderate    Inter Info   
[1], [2], [3]
D0539
 
Duloxetine
 
C18H19NOS
 
60835 
Moderate    Inter Info   
[1], [2], [3]
D0579
 
Ephedrine
 
C10H15NO
 
9294 
Moderate    Inter Info   
[1], [2], [3]
D0593
 
Ergotamine
 
C33H35N5O5
 
8223 
Moderate    Inter Info   
[1], [2], [3]
D0599
 
Escitalopram
 
C20H21FN2O
 
146570 
Moderate    Inter Info   
[1], [2], [3]
D0641
 
Fenfluramine
 
C12H16F3N
 
3337 
Moderate    Inter Info   
[1], [2], [3]
D0676
 
Fluoxetine
 
C17H18F3NO
 
3386 
Moderate    Inter Info   
[1], [2], [3]
D0678
 
Fluphenazine
 
C22H26F3N3OS
 
3372 
Moderate    Inter Info   
[1], [2], [3]
D0687
 
Fluvoxamine
 
C15H21F3N2O2
 
5324346 
Moderate    Inter Info   
[1], [2], [3]
D0743
 
Guanadrel
 
C10H19N3O2
 
38521 
Moderate    Inter Info   
[1], [2], [3]
D0744
 
Guanethidine
 
C10H22N4
 
3518 
Moderate    Inter Info   
[1], [2], [3]
D0795
 
Imipramine
 
C19H24N2
 
3696 
Moderate    Inter Info   
[1], [2], [3]
D0857
 
Isometheptene
 
C9H19N
 
22297 
Moderate    Inter Info   
[1], [2], [3]
D0920
 
Levomilnacipran
 
C15H22N2O
 
6917779 
Moderate    Inter Info   
[1], [2], [3]
D1708
 
Vortioxetine
 
C18H22N2S
 
9966051 
Moderate    Inter Info   
[1], [2], [3]
D0884
 
Labetalol
 
C19H24N2O3
 
3869 
Moderate    Inter Info   
[1], [2], [3]
D0937
 
Lisdexamfetamine
 
C15H25N3O
 
11597698 
Moderate    Inter Info   
[1], [2], [3]
D0957
 
Loxapine
 
C18H18ClN3O
 
3964 
Moderate    Inter Info   
[1], [2], [3]
D0979
 
Maprotiline
 
C20H23N
 
4011 
Moderate    Inter Info   
[1], [2], [3]
D0981
 
Mazindol
 
C16H13ClN2O
 
4020 
Moderate    Inter Info   
[1], [2], [3]
D1002
 
Mephentermine
 
C11H17N
 
3677 
Moderate    Inter Info   
[1], [2], [3]
D1010
 
Mesoridazine
 
C21H26N2OS2
 
4078 
Moderate    Inter Info   
[1], [2], [3]
D1012
 
Metamfetamine
 
C10H15N
 
10836 
Moderate    Inter Info   
[1], [2], [3]
D1013
 
Metaraminol
 
C9H13NO2
 
5906 
Moderate    Inter Info   
[1], [2], [3]
D1019
 
Methdilazine
 
C18H20N2S
 
14677 
Moderate    Inter Info   
[1], [2], [3]
D1026
 
Methotrimeprazine
 
C19H24N2OS
 
72287 
Moderate    Inter Info   
[1], [2], [3]
D1039
 
Methylphenidate
 
C14H19NO2
 
4158 
Moderate    Inter Info   
[1], [2], [3]
D1066
 
Milnacipran
 
C15H22N2O
 
65833 
Moderate    Inter Info   
[1], [2], [3]
D1075
 
Mirtazapine
 
C17H19N3
 
4205 
Moderate    Inter Info   
[1], [2], [3]
D1117
 
Nefazodone
 
C25H32ClN5O2
 
4449 
Moderate    Inter Info   
[1], [2], [3]
D1158
 
Nortriptyline
 
C19H21N
 
4543 
Moderate    Inter Info   
[1], [2], [3]
D1229
 
Paroxetine
 
C19H20FNO3
 
43815 
Moderate    Inter Info   
[1], [2], [3]
D1257
 
Perphenazine
 
C21H26ClN3OS
 
4748 
Moderate    Inter Info   
[1], [2], [3]
D1262
 
Phendimetrazine
 
C12H17NO
 
30487 
Moderate    Inter Info   
[1], [2], [3]
D1270
 
Phentermine
 
C10H15N
 
4771 
Moderate    Inter Info   
[1], [2], [3]
D1276
 
Phenylephrine
 
C9H13NO2
 
6041 
Moderate    Inter Info   
[1], [2], [3]
D1281
 
Phenylpropanolamine
 
C9H13NO
 
26934 
Moderate    Inter Info   
[1], [2], [3]
D1346
 
Prochlorperazine
 
C20H24ClN3S
 
4917 
Moderate    Inter Info   
[1], [2], [3]
D1351
 
Promazine
 
C17H20N2S
 
4926 
Moderate    Inter Info   
[1], [2], [3]
D1352
 
Promethazine
 
C17H20N2S
 
4927 
Moderate    Inter Info   
[1], [2], [3]
D1355
 
Propiomazine
 
C20H24N2OS
 
4940 
Moderate    Inter Info   
[1], [2], [3]
D1361
 
Protriptyline
 
C19H21N
 
4976 
Moderate    Inter Info   
[1], [2], [3]
D1363
 
Pseudoephedrine
 
C10H15NO
 
7028 
Moderate    Inter Info   
[1], [2], [3]
D1393
 
Reserpine
 
C33H40N2O9
 
5770 
Moderate    Inter Info   
[1], [2], [3]
D1461
 
Sertraline
 
C17H17Cl2N
 
68617 
Moderate    Inter Info   
[1], [2], [3]
D1464
 
Sibutramine
 
C17H26ClN
 
5210 
Moderate    Inter Info   
[1], [2], [3]
D1502
 
St. John's Wort
 
NA
 
NA
Moderate    Inter Info   
[1], [2], [3]
D1535
 
Tapentadol
 
C14H23NO
 
9838022 
Moderate    Inter Info   
[1], [2], [3]
D1572
 
Thiethylperazine
 
C22H29N3S2
 
5440 
Moderate    Inter Info   
[1], [2], [3]
D1574
 
Thioridazine
 
C21H26N2S2
 
5452 
Moderate    Inter Info   
[1], [2], [3]
D1624
 
Trazodone
 
C19H22ClN5O
 
5533 
Moderate    Inter Info   
[1], [2], [3]
D1637
 
Trifluoperazine
 
C21H24F3N3S
 
5566 
Moderate    Inter Info   
[1], [2], [3]
D1638
 
Triflupromazine
 
C18H19F3N2S
 
5568 
Moderate    Inter Info   
[1], [2], [3]
D1647
 
Trimipramine
 
C20H26N2
 
5584 
Moderate    Inter Info   
[1], [2], [3]
D1689
 
Venlafaxine
 
C17H27NO2
 
5656 
Moderate    Inter Info   
[1], [2], [3]
D1696
 
Vilazodone
 
C26H27N5O2
 
6918314 
Moderate    Inter Info   
[1], [2], [3]
References
1 Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):.
2 Product Information. Fycompa (perampanel). Eisai Inc, Teaneck, NJ.
3 Product Information. AdreView (iobenguane I-123). GE Healthcare, Princeton, NJ.