Details of Drug

Details of Drug

 Drug General Information (ID: D1812)
  Drug Name
Hyaluronidase
  Drug Type Protein/peptide
  Drug Synonymous
Hyaluronidase|37326-33-3|9001-54-1|6-(3,3-dimethyl-2-methylideneindol-1-yl)hexanoic acid;hydrobromide|1-Bromo-2,6-difluoro-3,5-dimethoxybenzene[2,6-difluoro-3,5-dimethoxybromobenzene|4-Amine-3-fluoropyridine|Pyridine 2-fluoro-3-methanol|4-Chloro-2-fluoro acetophenone|Pyridine2-chloro-3-boronic acid|Methyl 3-amino-5-fluoro benzoate|Methyl 2-Fluoro-3-nitro benzoate|Methyl 3-Fluoro-5-nitro benzoate|Pridine-4-methoxy-3-carboxaldehyde|Pyridine 4-methoxy-3-carboxaldehyde|Pyridine 3-methyl-5-carboxylic acid|s4424|AKOS025293742|AS03872|AS04570|AS04571|AS04678|AS04679|AS04680|AS04681|AS04689|AS04690|AS04692|AS04693|AS04734|AS04739|AS04772|AS04776|AS04777|AS04808|AS04814|AS04815|AS04830|AS04831|AS04832|AS04839|AS04842|AS04852|AS04853|AS04856|AS04859|AS04860|AS04861|AS04874|AS04880|AS04882|AS04929|AS04930|AS04935|AS04940|AS04942|AS04951|AS04955|AS04956|AS04957|AS04976|AS04979|AS05266|AS05636|AS05678|AS05679|AS05764|AS05765|AS05766|AS05914|AS05925|AS05926|AS06193|AS06617|AS06673|AS06716|AS06745|AS06771|Pyridine2-fluoro-6-methyl- 5-methanol|2-Fluoro-4-(trifluoromethylbenzaldehyde|3'-5'-Dimethoxy-4'-methylacetophenone|Pyridine2-Chloro-3-fluoro-5-boronicacid|5-Chloro-2-Isopropylamine-4-iodopyridine|PYRIDINE 2-FLUORO-3-BORONIC ACID|PYRIDINE 2-FLUORO-4-BORONIC ACID|PYRIDINE 2-FLUORO-5-BORONIC ACID|Pyridine2-fluoro-3-methyl-5-boronic acid|3-AMINE-4-FLUOROPHENYLBORONIC ACID|Pridine-2-chloro-6-methyl-3-boronic acid|PYRIDINE 2-CHLORO-3-CARBOXALDEHYDE|PYRIDINE 2-FLUORO-3-CARBOXALDEHYDE|Pyridine 2-fluoro-4-iodo-3-carboxaldehyde|PYRIDINE 2-FLUORO-6-CARBOXALDEHYDE|Pyridine2-Chloro-5-fluoro-4-carboxaldehyde|Pyridine 6-Fluoro-2-methyl-3-carboxaldehyde|Pyridine 5-fluoro-2-methoxy-4-carboxaldehyde|PYRIDINE 2-FLUORO-6-METHYL-3-BORONIC ACID|3-Methyl-5-[3,5-bis(trifluoromethyl)phenylpyridine|PYRIDINE 2-CHLORO-5-FLUORO-6-CARBOXALDEHYDE|PYRIDINE 5-FLUORO-2-METHOXY-3-CARBOXALDEHYDE|Methyl6-Chloro-2-[2,4-bis(chlorophenyl)pyridinebenzoate|(R)-ethyl 2-(4-fluorophenyl)-2-(4-oxopiperidin-1-yl)acetate HCl
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  Therapeutic Class Absorption Enhancers
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C17H24BrNO2
  InChI InChI=1S/C17H23NO2.BrH/c1-13-17(2,3)14-9-6-7-10-15(14)18(13)12-8-4-5-11-16(19)20;/h6-7,9-10H,1,4-5,8,11-12H2,2-3H3,(H,19,20);1H
  InChIKey SVMKEDBUSSWSFY-UHFFFAOYSA-N
  Canonical SMILES CC1(C(=C)N(C2=CC=CC=C21)CCCCCC(=O)O)C.Br
  External Link
Pubchem ID 91820602

Drug-Drug Interaction Network
  Sunburst Graph
AM007  Pharmacodynamic antagonistic effects
BM107  Attenuated pharmacological effects (Unspecific)
  Relation Graph
 Full list of drugs interacting with Hyaluronidase
      Pharmacodynamic antagonistic effects
   Attenuated pharmacological effects (Unspecific) Drug Num:  52
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0017
 
Acetylsalicylic acid
 
C9H8O4
 
2244 
Minor    Inter Info   
[1], [2], [3]
D0020
 
Acrivastine
 
C22H24N2O2
 
5284514 
Minor    Inter Info   
[1], [2], [3]
D0037
 
Alimemazine
 
C18H22N2S
 
5574 
Minor    Inter Info   
[1], [2], [3]
D0115
 
Astemizole
 
C28H31FN4O
 
2247 
Minor    Inter Info   
[1], [2], [3]
D0135
 
Azatadine
 
C20H22N2
 
19861 
Minor    Inter Info   
[1], [2], [3]
D0172
 
Betamethasone
 
C22H29FO5
 
9782 
Minor    Inter Info   
[1], [2], [3]
D0214
 
Brompheniramine
 
C16H19BrN2
 
6834 
Minor    Inter Info   
[1], [2], [3]
D0215
 
Budesonide
 
C25H34O6
 
5281004 
Minor    Inter Info   
[1], [2], [3]
D0259
 
Carbinoxamine
 
C16H19ClN2O
 
2564 
Minor    Inter Info   
[1], [2], [3]
D0305
 
Cetirizine
 
C21H25ClN2O3
 
2678 
Minor    Inter Info   
[1], [2], [3]
D0316
 
Chlorcyclizine
 
C18H21ClN2
 
2710 
Minor    Inter Info   
[1], [2], [3]
D0323
 
Chlorpheniramine
 
C16H19ClN2
 
2725 
Minor    Inter Info   
[1], [2], [3]
D0331
 
Choline salicylate
 
C12H19NO4
 
54686350 
Minor    Inter Info   
[1], [2], [3]
D0351
 
Clemastine
 
C21H26ClNO
 
26987 
Minor    Inter Info   
[1], [2], [3]
D0387
 
Conjugated estrogens
 
C18H21NaO5S
 
45357473 
Minor    Inter Info   
[1], [2], [3]
D0392
 
Corticotropin
 
C207H308N56O58S
 
16132265 
Minor    Inter Info   
[1], [2], [3]
D0403
 
Cyproheptadine
 
C21H21N
 
2913 
Minor    Inter Info   
[1], [2], [3]
D0448
 
Desloratadine
 
C19H19ClN2
 
124087 
Minor    Inter Info   
[1], [2], [3]
D0453
 
Dexamethasone
 
C22H29FO5
 
5743 
Minor    Inter Info   
[1], [2], [3]
D0456
 
Dexbrompheniramine
 
C16H19BrN2
 
16960 
Minor    Inter Info   
[1], [2], [3]
D0487
 
Diethylstilbestrol
 
C18H20O2
 
448537 
Minor    Inter Info   
[1], [2], [3]
D0489
 
Diflunisal
 
C13H8F2O3
 
3059 
Minor    Inter Info   
[1], [2], [3]
D0502
 
Diphenhydramine
 
C17H21NO
 
3100 
Minor    Inter Info   
[1], [2], [3]
D0605
 
Esterified estrogens
 
NA
 
NA
Minor    Inter Info   
[1], [2], [3]
D0606
 
Estradiol
 
C18H24O2
 
5757 
Minor    Inter Info   
[1], [2], [3]
D0608
 
Estramustine
 
C23H31Cl2NO3
 
259331 
Minor    Inter Info   
[1], [2], [3]
D0609
 
Estrone
 
C18H22O2
 
5870 
Minor    Inter Info   
[1], [2], [3]
D0610
 
Estrone sulfate
 
C18H22O5S
 
3001028 
Minor    Inter Info   
[1], [2], [3]
D0619
 
Ethinylestradiol
 
C20H24O2
 
5991 
Minor    Inter Info   
[1], [2], [3]
D0656
 
Fexofenadine
 
C32H39NO4
 
3348 
Minor    Inter Info   
[1], [2], [3]
D0773
 
Hydrocortisone
 
C21H30O5
 
5754 
Minor    Inter Info   
[1], [2], [3]
D0781
 
Hydroxyzine
 
C21H27ClN2O2
 
3658 
Minor    Inter Info   
[1], [2], [3]
D0917
 
Levocetirizine
 
C21H25ClN2O3
 
1549000 
Minor    Inter Info   
[1], [2], [3]
D0950
 
Loratadine
 
C22H23ClN2O2
 
3957 
Minor    Inter Info   
[1], [2], [3]
D1006
 
Mepyramine
 
C17H23N3O
 
4992 
Minor    Inter Info   
[1], [2], [3]
D1011
 
Mestranol
 
C21H26O2
 
6291 
Minor    Inter Info   
[1], [2], [3]
D1019
 
Methdilazine
 
C18H20N2S
 
14677 
Minor    Inter Info   
[1], [2], [3]
D1041
 
Methylprednisolone
 
C22H30O5
 
6741 
Minor    Inter Info   
[1], [2], [3]
D1264
 
Phenindamine
 
C19H19N
 
11291 
Minor    Inter Info   
[1], [2], [3]
D1272
 
Phenyl salicylate
 
C13H10O3
 
8361 
Minor    Inter Info   
[1], [2], [3]
D1282
 
Phenyltoloxamine
 
C17H21NO
 
7077 
Minor    Inter Info   
[1], [2], [3]
D1332
 
Prednisolone
 
C21H28O5
 
5755 
Minor    Inter Info   
[1], [2], [3]
D1334
 
Prednisone
 
C21H26O5
 
5865 
Minor    Inter Info   
[1], [2], [3]
D1352
 
Promethazine
 
C17H20N2S
 
4927 
Minor    Inter Info   
[1], [2], [3]
D1370
 
Quinestrol
 
C25H32O2
 
9046 
Minor    Inter Info   
[1], [2], [3]
D1439
 
Salicylic acid (sodium)
 
C7H6O3
 
338 
Minor    Inter Info   
[1], [2], [3]
D1442
 
Salsalate
 
C14H10O5
 
5161 
Minor    Inter Info   
[1], [2], [3]
D1555
 
Terfenadine
 
C32H41NO2
 
5405 
Minor    Inter Info   
[1], [2], [3]
D1563
 
Tetracosactide
 
C136H210N40O31S
 
16133802 
Minor    Inter Info   
[1], [2], [3]
D1628
 
Triamcinolone
 
C21H27FO6
 
31307 
Minor    Inter Info   
[1], [2], [3]
D1649
 
Tripelennamine
 
C16H21N3
 
5587 
Minor    Inter Info   
[1], [2], [3]
D1650
 
Triprolidine
 
C19H22N2
 
5282443 
Minor    Inter Info   
[1], [2], [3]
References
1 Fuhr U, Maier-Bruggemann A, Blume H, et al. "Grapefruit juice increases oral nimodipine bioavailability." Int J Clin Pharmacol Ther 36 (1998): 126-32. [PMID: 9562227]
2 Gunston GD, Mehta U "Potentially serious drug interactions with grapefruit juice." S Afr Med J 90 (2000): 41. [PMID: 10721388]
3 Product Information. Vitrase (hyaluronidase). Bausch and Lomb, Rochester, NY.