Details of Drug

Details of Drug

 Drug General Information (ID: D1810)
  Drug Name
Human vaccinia virus immune globulin
  Drug Type Polyclonal antibody
  Drug Synonymous
Human vaccinia virus immune globulin; Human vaccinia immune globulin; Vaccinia immune globulin; Vaccinia immune globulin intravenous (human); Vaccinia immunoglobulins; VIG; DB14112
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  Therapeutic Class Immune Globulins

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM100  Antagonize the effect of vaccine/toxoid
BM109  Increased risk of other adverse reactions (Unspecific)
  Relation Graph
 Full list of drugs interacting with Human vaccinia virus immune globulin
      Pharmacodynamic additive effects
   Increased risk of other adverse reactions (Unspecific) Drug Num:  4
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0621
 
Ethotoin
 
C11H12N2O2
 
3292 
Moderate    Inter Info   
[3], [4], [5]
D0697
 
Fosphenytoin
 
C16H15N2O6P
 
56339 
Moderate    Inter Info   
[3], [4], [5]
D1003
 
Mephenytoin
 
C12H14N2O2
 
4060 
Moderate    Inter Info   
[3], [4], [5]
D1283
 
Phenytoin
 
C15H12N2O2
 
1775 
Moderate    Inter Info   
[3], [4], [5]
      Pharmacodynamic antagonistic effects
   Antagonize the effect of vaccine/toxoid Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1744
 
Bacillus calmette-guerin substrain tice live antigen
 
NA
 
NA
Moderate    Inter Info   
[1], [2]
References
1 CDC. Centers for Disease Control and Prevention/ "Recommendations of the advisory committtee on immunization practices (ACIP): use of vaccines and immune globulins in persons with altered immunocompetence." MMWR Morb Mortal Wkly Rep 42(RR-04) (1993): 1-18. [PMID: 20300058]
2 Interference of immune globulin with measles and rubella immunization. Eur J Pediatr 152 (1993): 536. [PMID: 8335028]
3 Fenoglio JJ, McAllister HA, Mullick FG "Drug related myocarditis: I. Hypersensitivity myocarditis." Hum Pathol 12 (1981): 900-7. [PMID: 7298049]
4 Koehler PJ, Koudstaal J "Lethal hypersensitivity myocarditis associated with the use of intravenous gammaglobulin for Guillan-Barre syndrome, in combination with phenytoin." J Neurol 243 (1996): 366-7. [PMID: 8965113]
5 Mostella J, Pieroni R, Jones R, Finch CK "Anticonvulsant hypersensitivity syndrome: treatment with corticosteroids and intravenous immunoglobulin." South Med J 97 (2004): 319-21. [PMID: 15043348]