Details of Drug

Details of Drug

 Drug General Information (ID: D1792)
  Drug Name
Gadobutrol
  Drug Type Small molecule
  Drug Synonymous
Gadavist (TN)
    Click to Show/Hide
  Disease Class 5C61: Carbohydrate absorption/transport disorder
  Therapeutic Class Diagnostic Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C18H31GdN4O9
  InChI 1S/C18H34N4O9.Gd/c23-12-14(15(25)13-24)22-7-5-20(10-17(28)29)3-1-19(9-16(26)27)2-4-21(6-8-22)11-18(30)31;/h14-15,23-25H,1-13H2,(H,26,27)(H,28,29)(H,30,31);/q;+3/p-3/t14-,15-;/m1./s1
  InChIKey ZPDFIIGFYAHNSK-CTHHTMFSSA-K
  Canonical SMILES C1CN(CCN(CCN(CCN1CC(=O)[O-])CC(=O)[O-])C(CO)C(CO)O)CC(=O)[O-].[Gd+3]
  External Link
Pubchem ID 6102852
CAS Number CAS 770691-21-9
TTD ID D0P1IZ

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
BM048  Increased risk of angioedema/anaphylactoid reactions
BM072  Increased risk of nephrotoxicity
  Relation Graph
 Full list of drugs interacting with Gadobutrol
      Pharmacodynamic additive effects
   Increased risk of angioedema/anaphylactoid reactions Drug Num:  22
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0010
 
Acebutolol
 
C18H28N2O4
 
1978 
Moderate    Inter Info   
[1], [2], [3]
D0117
 
Atenolol
 
C14H22N2O3
 
2249 
Moderate    Inter Info   
[1], [2], [3]
D0173
 
Betaxolol
 
C18H29NO3
 
2369 
Moderate    Inter Info   
[1], [2], [3]
D0174
 
Betaxolol (ophthalmic)
 
C18H29NO3
 
2369 
Moderate    Inter Info   
[1], [2], [3]
D0188
 
Bisoprolol
 
C18H31NO4
 
2405 
Moderate    Inter Info   
[1], [2], [3]
D0265
 
Carteolol
 
C16H24N2O3
 
2583 
Moderate    Inter Info   
[1], [2], [3]
D0266
 
Carteolol (ophthalmic)
 
C16H24N2O3
 
2583 
Moderate    Inter Info   
[1], [2], [3]
D0267
 
Carvedilol
 
C24H26N2O4
 
2585 
Moderate    Inter Info   
[1], [2], [3]
D0602
 
Esmolol
 
C16H25NO4
 
59768 
Moderate    Inter Info   
[1], [2], [3]
D0914
 
Levobetaxolol (ophthalmic)
 
C18H29NO3
 
60657 
Moderate    Inter Info   
[1], [2], [3]
D0884
 
Labetalol
 
C19H24N2O3
 
3869 
Moderate    Inter Info   
[1], [2], [3]
D0915
 
Levobunolol (ophthalmic)
 
C17H25NO3
 
39468 
Moderate    Inter Info   
[1], [2], [3]
D1045
 
Metipranolol (ophthalmic)
 
C17H27NO4
 
31477 
Moderate    Inter Info   
[1], [2], [3]
D1049
 
Metoprolol
 
C15H25NO3
 
4171 
Moderate    Inter Info   
[1], [2], [3]
D1098
 
Nadolol
 
C17H27NO4
 
39147 
Moderate    Inter Info   
[1], [2], [3]
D1114
 
Nebivolol
 
C22H25F2NO4
 
71301 
Moderate    Inter Info   
[1], [2], [3]
D1244
 
Penbutolol
 
C18H29NO2
 
37464 
Moderate    Inter Info   
[1], [2], [3]
D1293
 
Pindolol
 
C14H20N2O2
 
4828 
Moderate    Inter Info   
[1], [2], [3]
D1357
 
Propranolol
 
C16H21NO2
 
4946 
Moderate    Inter Info   
[1], [2], [3]
D1498
 
Sotalol
 
C12H20N2O3S
 
5253 
Moderate    Inter Info   
[1], [2], [3]
D1585
 
Timolol
 
C13H24N4O3S
 
33624 
Moderate    Inter Info   
[1], [2], [3]
D1586
 
Timolol (ophthalmic)
 
C13H24N4O3S
 
33624 
Moderate    Inter Info   
[1], [2], [3]
   Increased risk of nephrotoxicity Drug Num:  3
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1826
 
Iopanoic acid
 
C11H12I3NO2
 
3735 
Moderate    Inter Info   
[4], [5], [6]
D0835
 
Iopodic acid
 
C12H13I3N2O2
 
5241 
Moderate    Inter Info   
[4], [5], [6]
D1915
 
Tyropanoic acid
 
C15H18I3NO3
 
5611 
Moderate    Inter Info   
[4], [5], [6]
References
1 Cerner Multum, Inc. "Australian Product Information.".
2 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
3 EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports.".
4 Product Information. Ultravist (iopromide). Berlex, Richmond, CA.
5 Product Information. Visipaque (iodixanol). Nycomed Inc, Princeton, NJ.
6 Product Information. Omniscan (gadodiamide). Novation, Irving, TX.