Details of Drug

Details of Drug

 Drug General Information (ID: D1738)
  Drug Name
Angiotensin II
  Drug Type Hormones
  Drug Synonymous
Human angiotensin II; Angiotensin II human; 4474-91-3; Angiotensin II (mouse); Angiotensin II (human); Giapreza; Ang II; 5-Isoleucine-angiotensin II; 5-L-Isoleucineangiotensin II; Ile(5)-angiotensin II; 1-8-Angiotensin I; isoleucine(5)-angiotensin II;Angiotensin II, human; Isoleucine5-angiotensin II; Angiotensin II, ile(5)-; Angiotensin ii [INN:JAN]
    Click to Show/Hide
  Disease Class BA04: Secondary hypertension
  Therapeutic Class Hormone Modulators
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C50H71N13O12
  InChI 1S/C50H71N13O12/c1-5-28(4)41(47(72)59-36(23-31-25-54-26-56-31)48(73)63-20-10-14-38(63)45(70)60-37(49(74)75)22-29-11-7-6-8-12-29)62-44(69)35(21-30-15-17-32(64)18-16-30)58-46(71)40(27(2)3)61-43(68)34(13-9-19-55-50(52)53)57-42(67)33(51)24-39(65)66/h6-8,11-12,15-18,25-28,33-38,40-41,64H,5,9-10,13-14,19-24,51H2,1-4H3,(H,54,56)(H,57,67)(H,58,71)(H,59,72)(H,60,70)(H,61,68)(H,62,69)(H,65,66)(H,74,75)(H4,52,53,55)/t28-,33-,34-,35-,36-,37-,38-,40-,41-/m0/s1
  InChIKey CZGUSIXMZVURDU-JZXHSEFVSA-N
  Canonical SMILES CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N
  External Link
Pubchem ID 172198
CAS Number CAS 4474-91-3
CHEBI ID CHEBI:2719
TTD ID D0G6SE

Drug-Drug Interaction Network
  Sunburst Graph
AM007  Pharmacodynamic antagonistic effects
BM089  Antagonize the effect of antihypertensive agents
  Relation Graph
 Full list of drugs interacting with Angiotensin II
      Pharmacodynamic antagonistic effects
   Antagonize the effect of antihypertensive agents Drug Num:  7
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0138
 
Azilsartan medoxomil
 
C30H24N4O8
 
135409642 
Moderate    Inter Info   
[1], [2], [3]
D0587
 
Eprosartan
 
C23H24N2O4S
 
5281037 
Moderate    Inter Info   
[1], [2], [3]
D0844
 
Irbesartan
 
C25H28N6O
 
3749 
Moderate    Inter Info   
[1], [2], [3]
D0954
 
Losartan
 
C22H23ClN6O
 
3961 
Moderate    Inter Info   
[1], [2], [3]
D1170
 
Olmesartan
 
C24H26N6O3
 
158781 
Moderate    Inter Info   
[1], [2], [3]
D1545
 
Telmisartan
 
C33H30N4O2
 
65999 
Moderate    Inter Info   
[1], [2], [3]
D1679
 
Valsartan
 
C24H29N5O3
 
60846 
Moderate    Inter Info   
[1], [2], [3]
References
1 Product Information. Cozaar (losartan). Merck &amp Co, Inc, West Point, PA.
2 Product Information. Diovan (valsartan). Novartis Pharmaceuticals, East Hanover, NJ.
3 Product Information. Giapreza (angiotensin II). La Jolla Pharmaceutical, San Diego, CA.