Details of Drug

Details of Drug

 Drug General Information (ID: D1732)
  Drug Name
Abaloparatide
  Drug Type Hormones
  Drug Synonymous
Abaloparatide|Abaloparatide acetate|247062-33-5
    Click to Show/Hide
  Disease Class FB83: Low bone mass disorder
  Therapeutic Class Hormone Modulators
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C174H300N56O49
  InChI InChI=1S/C174H300N56O49/c1-26-93(20)136(228-165(274)126(80-232)224-141(250)101(39-28-32-56-176)200-129(236)78-195-140(249)100(38-27-31-55-175)201-161(270)123(73-133(243)244)223-160(269)121(71-98-76-190-82-197-98)220-158(267)118(68-90(14)15)216-155(264)114(64-86(6)7)213-148(257)107(45-50-127(180)234)207-159(268)120(70-97-75-189-81-196-97)219-151(260)111(49-54-132(241)242)209-164(273)125(79-231)225-167(276)135(92(18)19)227-139(248)94(21)179)168(277)210-108(46-51-128(181)235)149(258)222-124(74-134(245)246)162(271)217-112(62-84(2)3)152(261)205-105(44-37-61-194-173(187)188)143(252)203-103(42-35-59-192-171(183)184)142(251)204-104(43-36-60-193-172(185)186)144(253)206-110(48-53-131(239)240)150(259)214-115(65-87(8)9)154(263)215-113(63-85(4)5)153(262)208-109(47-52-130(237)238)147(256)202-102(40-29-33-57-177)145(254)211-116(66-88(10)11)156(265)218-119(69-91(16)17)166(275)230-174(24,25)170(279)226-106(41-30-34-58-178)146(255)212-117(67-89(12)13)157(266)221-122(72-99-77-191-83-198-99)163(272)229-137(96(23)233)169(278)199-95(22)138(182)247/h75-77,81-96,100-126,135-137,231-233H,26-74,78-80,175-179H2,1-25H3,(H2,180,234)(H2,181,235)(H2,182,247)(H,189,196)(H,190,197)(H,191,198)(H,195,249)(H,199,278)(H,200,236)(H,201,270)(H,202,256)(H,203,252)(H,204,251)(H,205,261)(H,206,253)(H,207,268)(H,208,262)(H,209,273)(H,210,277)(H,211,254)(H,212,255)(H,213,257)(H,214,259)(H,215,263)(H,216,264)(H,217,271)(H,218,265)(H,219,260)(H,220,267)(H,221,266)(H,222,258)(H,223,269)(H,224,250)(H,225,276)(H,226,279)(H,227,248)(H,228,274)(H,229,272)(H,230,275)(H,237,238)(H,239,240)(H,241,242)(H,243,244)(H,245,246)(H4,183,184,192)(H4,185,186,193)(H4,187,188,194)
  InChIKey BVISQZFBLRSESR-UHFFFAOYSA-N
  Canonical SMILES CCC(C)C(C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C)(C)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC1=CN=CN1)C(=O)NC(C(C)O)C(=O)NC(C)C(=O)N)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)O)NC(=O)C(CC2=CN=CN2)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)N)NC(=O)C(CC3=CN=CN3)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)C(C)N
  External Link
Pubchem ID 145705876
CAS Number CAS 247062-33-5
TTD ID D02CII

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
BM083  Potentiated the pharmacological effects (Unspecific)
BM108  Increased risk of hypercalcemia
  Relation Graph
 Full list of drugs interacting with Abaloparatide
      Pharmacodynamic additive effects
   Potentiated the pharmacological effects (Unspecific) Drug Num:  2
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0490
 
Digitoxin
 
C41H64O13
 
441207 
Moderate    Inter Info   
[3], [4]
D0491
 
Digoxin
 
C41H64O14
 
2724385 
Moderate    Inter Info   
[3], [4]
   Increased risk of hypercalcemia Drug Num:  2
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1753
 
Calcipotriol (topical)
 
C27H40O3
 
5288783 
Moderate    Inter Info   
[1], [2]
D1754
 
Calcitriol (topical)
 
C27H44O3
 
5280453 
Moderate    Inter Info   
[1], [2]
References
1 Product Information. Vectical (calcitriol topical). Galderma Laboratories Inc, Cranbury, NJ.
2 Product Information. Dovonex (calcipotriene). Westwood Squibb Pharmaceutical Corporation, Eatontown, NJ.
3 Product Information. Forteo (teriparatide). Lilly, Eli and Company, Indianapolis, IN.
4 Benson CT, Voelker JR "Teriparatide has no effect on the calcium-mediated pharmacodynamics of digoxin." Clin Pharmacol Ther 73 (2003): 87-94. [PMID: 12545147]