Details of Drug

Drug General Information (ID: D1691)
Drug Name	Verteporfin
Drug Type	Small molecule
Drug Synonymous	Visudyne (TN) Click to Show/Hide
Disease Class	EA90: Psoriasis
Therapeutic Class	Antineoplastics
Structure
Structure	3D Structure		2D Structure
Formula	C82H84N8O16
InChI	1S/2C41H42N4O8/c1-9-23-20(2)29-17-34-27-13-10-26(39(49)52-7)38(40(50)53-8)41(27,5)35(45-34)19-30-22(4)24(11-14-36(46)47)32(44-30)18-33-25(12-15-37(48)51-6)21(3)28(43-33)16-31(23)42-29;1-9-23-20(2)29-17-34-27-13-10-26(39(49)52-7)38(40(50)53-8)41(27,5)35(45-34)19-30-22(4)25(12-15-37(48)51-6)33(44-30)18-32-24(11-14-36(46)47)21(3)28(43-32)16-31(23)42-29/h29-10,13,16-19,38,42,44H,1,11-12,14-15H2,2-8H3,(H,46,47)/t238-,41+/m00/s1
InChIKey	NJLRKAMQPVVOIU-IDLGWYNRSA-N
Canonical SMILES	CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5C6(C(C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)OC)C(=C3C)CCC(=O)O)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5C6(C(C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)O)C(=C3C)CCC(=O)OC)C=C
External Link
	Pubchem ID	11980904
	TTD ID	D0I3XG
	VARIDT ID	DR00209

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM050 Increased risk of bleeding BM075 Increased risk of photosensitivity reactions BM107 Attenuated pharmacological effects (Unspecific) BM109 Increased risk of other adverse reactions (Unspecific)
Relation Graph

Full list of drugs interacting with Verteporfin
Pharmacodynamic additive effects
	Increased risk of bleeding					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0368		Clove	NA	NA	Minor		Inter Info	[14], [15], [16], [17]
	Increased risk of photosensitivity reactions					Drug Num: 111
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0062		Aminolevulinic acid	C5H9NO3	137	Major		Inter Info	[1], [2]
D0013		Acetohexamide	C15H20N2O4S	1989	Moderate		Inter Info	[5], [6], [1], [3]
D0018		Acitretin	C21H26O3	5284513	Moderate		Inter Info	[5], [6], [1], [3]
D0024		Adapalene (topical)	C28H28O3	60164	Moderate		Inter Info	[5], [6], [3]
D0158		Bendroflumethiazide	C15H14F3N3O4S2	2315	Moderate		Inter Info	[5], [6], [1], [3]
D0178		Bexarotene	C24H28O2	82146	Moderate		Inter Info	[5], [6], [1], [3]
D0179		Bexarotene (topical)	C24H28O2	82146	Moderate		Inter Info	[5], [6], [3]
D0306		Cetuximab	NA	NA	Moderate		Inter Info	[5], [6], [1], [3]
D0326		Chlorthalidone	C14H11ClN2O4S	2732	Moderate		Inter Info	[5], [6], [1], [3]
D0419		Dapsone	C12H12N2O2S	2955	Moderate		Inter Info	[5], [6], [1], [3]
D0530		Doxycycline	C22H24N2O8	54671203	Moderate		Inter Info	[5], [6], [1], [3]
D0531		Doxycycline (topical)	C22H24N2O8	54671203	Moderate		Inter Info	[5], [6], [3]
D0713		Gefitinib	C22H24ClFN4O3	123631	Moderate		Inter Info	[5], [6], [1], [3]
D0727		Glimepiride	C24H34N4O5S	3476	Moderate		Inter Info	[5], [6], [1], [3]
D0740		Grepafloxacin	C19H22FN3O3	72474	Moderate		Inter Info	[5], [6], [1], [3]
D1092		Moxifloxacin	C21H24FN3O4	152946	Moderate		Inter Info	[5], [6], [1], [3]
D1346		Prochlorperazine	C20H24ClN3S	4917	Moderate		Inter Info	[5], [6], [1], [3]
D1351		Promazine	C17H20N2S	4926	Moderate		Inter Info	[5], [6], [1], [3]
D1513		Sulfadiazine	C10H10N4O2S	5215	Moderate		Inter Info	[5], [6], [1], [3]
D1519		Sulfisoxazole	C11H13N3O3S	5344	Moderate		Inter Info	[5], [6], [1], [3]
D1572		Thiethylperazine	C22H29N3S2	5440	Moderate		Inter Info	[5], [6], [1], [3]
D1611		Torasemide	C16H20N4O3S	41781	Moderate		Inter Info	[5], [6], [3]
D0012		Acetazolamide	C4H6N4O3S2	1986	Moderate		Inter Info	[5], [6], [1], [3]
D0026		Afatinib	C24H25ClFN5O3	10184653	Moderate		Inter Info	[5], [6], [1], [3]
D0031		Alectinib	C30H34N4O2	49806720	Moderate		Inter Info	[5], [6], [1], [3]
D0037		Alimemazine	C18H22N2S	5574	Moderate		Inter Info	[5], [6], [3]
D0039		Alitretinoin (topical)	C20H28O2	449171	Moderate		Inter Info	[5], [6], [3]
D0063		Aminolevulinic acid (topical)	C5H9NO3	137	Moderate		Inter Info	[7], [5], [8]
D0066		Amiodarone	C25H29I2NO3	2157	Moderate		Inter Info	[5], [6], [1], [3]
D0129		Avapritinib	C26H27FN10	118023034	Moderate		Inter Info	[5], [6], [1], [3]
D0166		Benzthiazide	C15H14ClN3O4S3	2343	Moderate		Inter Info	[5], [6], [1], [3]
D0180		Bicalutamide	C18H14F4N2O4S	2375	Moderate		Inter Info	[5], [6], [1], [3]
D0217		Bumetanide	C17H20N2O5S	2471	Moderate		Inter Info	[5], [6], [1], [3]
D0298		Celecoxib	C17H14F3N3O2S	2662	Moderate		Inter Info	[5], [6], [1], [3]
D0321		Chlorothiazide	C7H6ClN3O4S2	2720	Moderate		Inter Info	[5], [6], [1], [3]
D0324		Chlorpromazine	C17H19ClN2S	2726	Moderate		Inter Info	[5], [6], [1], [3]
D0325		Chlorpropamide	C10H13ClN2O3S	2727	Moderate		Inter Info	[5], [6], [1], [3]
D0340		Cinoxacin	C12H10N2O5	2762	Moderate		Inter Info	[5], [6], [1], [3]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Moderate		Inter Info	[5], [6], [1], [3]
D0374		Coal tar (topical)	NA	NA	Moderate		Inter Info	[5], [6], [3]
D0376		Cobimetinib	C21H21F3IN3O2	16222096	Moderate		Inter Info	[5], [6], [1], [3]
D0406		Dabrafenib	C23H20F3N5O2S2	44462760	Moderate		Inter Info	[5], [6], [1], [3]
D0441		Demeclocycline	C21H21ClN2O8	54680690	Moderate		Inter Info	[5], [6], [1], [3]
D0573		Enoxacin	C15H17FN4O3	3229	Moderate		Inter Info	[5], [6], [1], [3]
D0589		Eravacycline	C27H31FN4O8	54726192	Moderate		Inter Info	[5], [6], [1], [3]
D0595		Erlotinib	C22H23N3O4	176870	Moderate		Inter Info	[5], [6], [1], [3]
D0613		Etacrynic acid	C13H12Cl2O4	3278	Moderate		Inter Info	[5], [6], [3]
D0704		Furosemide	C12H11ClN2O5S	3440	Moderate		Inter Info	[5], [6], [1], [3]
D0712		Gatifloxacin	C19H22FN3O4	5379	Moderate		Inter Info	[5], [6], [1], [3]
D0716		Gemifloxacin	C18H20FN5O4	9571107	Moderate		Inter Info	[5], [6], [1], [3]
D0728		Glipizide	C21H27N5O4S	3478	Moderate		Inter Info	[5], [6], [1], [3]
D0730		Glyburide	C23H28ClN3O5S	3488	Moderate		Inter Info	[5], [6], [1], [3]
D0771		Hydrochlorothiazide	C7H8ClN3O4S2	3639	Moderate		Inter Info	[5], [6], [1], [3]
D0775		Hydroflumethiazide	C8H8F3N3O4S2	3647	Moderate		Inter Info	[5], [6], [1], [3]
D0793		Imatinib	C29H31N7O	5291	Moderate		Inter Info	[5], [6], [1], [3]
D0796		Imiquimod (topical)	C14H16N4	57469	Moderate		Inter Info	[5], [6], [3]
D0798		Indapamide	C16H16ClN3O3S	3702	Moderate		Inter Info	[5], [6], [1], [3]
D0863		Isotretinoin	C20H28O2	5282379	Moderate		Inter Info	[5], [6], [1], [3]
D0894		Lapatinib	C29H26ClFN4O4S	208908	Moderate		Inter Info	[5], [6], [1], [3]
D0919		Levofloxacin	C18H20FN3O4	149096	Moderate		Inter Info	[5], [6], [1], [3]
D0943		Lomefloxacin	C17H19F2N3O3	3948	Moderate		Inter Info	[5], [6], [1], [3]
D1010		Mesoridazine	C21H26N2OS2	4078	Moderate		Inter Info	[5], [6], [1], [3]
D1019		Methdilazine	C18H20N2S	14677	Moderate		Inter Info	[5], [6], [1], [3]
D1025		Methotrexate	C20H22N8O5	126941	Moderate		Inter Info	[5], [6], [1], [3]
D1026		Methotrimeprazine	C19H24N2OS	72287	Moderate		Inter Info	[5], [6], [1], [3]
D1028		Methoxsalen	C12H8O4	4114	Moderate		Inter Info	[7], [6], [1], [9], [10]
D1029		Methoxsalen (topical)	C12H8O4	4114	Moderate		Inter Info	[5], [6], [3]
D1033		Methyl aminolevulinate (topical)	C6H11NO3	157922	Moderate		Inter Info	[7], [5], [8]
D1048		Metolazone	C16H16ClN3O3S	4170	Moderate		Inter Info	[5], [6], [1], [3]
D1070		Minocycline	C23H27N3O7	54675783	Moderate		Inter Info	[5], [6], [1], [3]
D1071		Minocycline (topical)	C23H27N3O7	54675783	Moderate		Inter Info	[5], [6], [3]
D1102		Nalidixic acid	C12H12N2O3	4421	Moderate		Inter Info	[5], [6], [1], [3]
D1155		Norfloxacin	C16H18FN3O3	4539	Moderate		Inter Info	[5], [6], [1], [3]
D1165		Ofloxacin	C18H20FN3O4	4583	Moderate		Inter Info	[5], [6], [1], [3]
D1175		Omadacycline	C29H40N4O7	54697325	Moderate		Inter Info	[5], [6], [1], [3]
D1209		Oxytetracycline	C22H24N2O9	54675779	Moderate		Inter Info	[5], [6], [1], [3]
D1220		Panitumumab	NA	NA	Moderate		Inter Info	[5], [6], [1], [3]
D1257		Perphenazine	C21H26ClN3OS	4748	Moderate		Inter Info	[5], [6], [1], [3]
D1299		Pirfenidone	C12H11NO	40632	Moderate		Inter Info	[5], [6], [1], [3]
D1311		Polythiazide	C11H13ClF3N3O4S3	4870	Moderate		Inter Info	[5], [6], [1], [3]
D1314		Porfimer sodium	C68H74N8O11	135577896	Moderate		Inter Info	[11], [5], [12]
D1352		Promethazine	C17H20N2S	4927	Moderate		Inter Info	[5], [6], [1], [3]
D1355		Propiomazine	C20H24N2OS	4940	Moderate		Inter Info	[5], [6], [1], [3]
D1445		Sarecycline	C24H29N3O8	54681908	Moderate		Inter Info	[5], [6], [1], [3]
D1471		Simeprevir	C38H47N5O7S2	24873435	Moderate		Inter Info	[5], [6], [1], [3]
D1499		Sparfloxacin	C19H22F2N4O3	60464	Moderate		Inter Info	[5], [6], [1], [3]
D1502		St. John's Wort	NA	NA	Moderate		Inter Info	[5], [6], [1], [3]
D1514		Sulfadoxine	C12H14N4O4S	17134	Moderate		Inter Info	[5], [6], [1], [3]
D1515		Sulfamethizole	C9H10N4O2S2	5328	Moderate		Inter Info	[5], [6], [1], [3]
D1516		Sulfamethoxazole	C10H11N3O3S	5329	Moderate		Inter Info	[5], [6], [1], [3]
D1517		Sulfasalazine	C18H14N4O5S	5339	Moderate		Inter Info	[5], [6], [1], [3]
D1537		Tazarotene (topical)	C21H21NO2S	5381	Moderate		Inter Info	[5], [6], [3]
D1564		Tetracycline	C22H24N2O8	54675776	Moderate		Inter Info	[5], [6], [1], [3]
D1565		Tetracycline (topical)	C22H24N2O8	54675776	Moderate		Inter Info	[5], [6], [3]
D1574		Thioridazine	C21H26N2S2	5452	Moderate		Inter Info	[5], [6], [1], [3]
D1582		Tigecycline	C29H39N5O8	54686904	Moderate		Inter Info	[5], [6], [1], [3]
D1592		Tipranavir	C31H33F3N2O5S	54682461	Moderate		Inter Info	[5], [6], [1], [3]
D1601		Tolazamide	C14H21N3O3S	5503	Moderate		Inter Info	[5], [6], [1], [3]
D1603		Tolbutamide	C12H18N2O3S	5505	Moderate		Inter Info	[5], [6], [1], [3]
D1626		Tretinoin	C20H28O2	444795	Moderate		Inter Info	[5], [6], [1], [3]
D1627		Tretinoin (topical)	C20H28O2	444795	Moderate		Inter Info	[5], [6], [3]
D1633		Trichlormethiazide	C8H8Cl3N3O4S2	5560	Moderate		Inter Info	[5], [6], [1], [3]
D1636		Trifarotene (topical)	C29H33NO4	11518241	Moderate		Inter Info	[5], [6], [3]
D1637		Trifluoperazine	C21H24F3N3S	5566	Moderate		Inter Info	[5], [6], [1], [3]
D1638		Triflupromazine	C18H19F3N2S	5568	Moderate		Inter Info	[5], [6], [1], [3]
D1648		Trioxsalen	C14H12O3	5585	Moderate		Inter Info	[5], [6], [1], [3]
D1657		Trovafloxacin	C20H15F3N4O3	62959	Moderate		Inter Info	[5], [6], [1], [3]
D1674		Valdecoxib	C16H14N2O3S	119607	Moderate		Inter Info	[5], [6], [1], [3]
D1681		Vandetanib	C22H24BrFN4O2	3081361	Moderate		Inter Info	[5], [6], [1], [3]
D1687		Vemurafenib	C23H18ClF2N3O3S	42611257	Moderate		Inter Info	[5], [6], [1], [3]
D1706		Voriconazole	C16H14F3N5O	71616	Moderate		Inter Info	[5], [6], [1], [3]
	Increased risk of other adverse reactions (Unspecific)					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1875		Ranibizumab (ophthalmic)	NA	NA	Moderate		Inter Info	[13]
Pharmacodynamic antagonistic effects
	Attenuated pharmacological effects (Unspecific)					Drug Num: 102
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0005		Abciximab	NA	NA	Moderate		Inter Info	[3], [4]
D0036		Alfuzosin	C19H27N5O4	2092	Moderate		Inter Info	[3], [4]
D0102		Ardeparin	C26H42N2O37S5	772	Moderate		Inter Info	[3], [4]
D0104		Argatroban	C23H36N6O5S	92722	Moderate		Inter Info	[3], [4]
D0189		Bivalirudin	C98H138N24O33	16129704	Moderate		Inter Info	[3], [4]
D0481		Dicoumarol	C19H12O6	54676038	Moderate		Inter Info	[3], [4]
D0588		Eptifibatide	C35H49N11O9S2	448812	Moderate		Inter Info	[3], [4]
D0743		Guanadrel	C10H19N3O2	38521	Moderate		Inter Info	[3], [4]
D0800		Indomethacin	C19H16ClNO4	3715	Moderate		Inter Info	[3], [4]
D0904		Lepirudin	C287H440N80O111S6	118856773	Moderate		Inter Info	[3], [4]
D1072		Minoxidil	C9H15N5O	4201	Moderate		Inter Info	[3], [4]
D1848		Minoxidil (topical)	C9H15N5O	4201	Moderate		Inter Info	[3], [4]
D1147		Nitroprusside	C5FeN6O	11953891	Moderate		Inter Info	[3], [4]
D1331		Prazosin	C19H21N5O4	4893	Moderate		Inter Info	[3], [4]
D1393		Reserpine	C33H40N2O9	5770	Moderate		Inter Info	[3], [4]
D1465		Sildenafil	C22H30N6O4S	135398744	Moderate		Inter Info	[3], [4]
D1581		Ticlopidine	C14H14ClNS	5472	Moderate		Inter Info	[3], [4]
D1625		Treprostinil	C23H34O5	6918140	Moderate		Inter Info	[3], [4]
D0017		Acetylsalicylic acid	C9H8O4	2244	Moderate		Inter Info	[3], [4]
D0046		Alprostadil	C20H34O5	5280723	Moderate		Inter Info	[3], [4]
D0053		Ambrisentan	C22H22N2O4	6918493	Moderate		Inter Info	[3], [4]
D0083		Amyl Nitrite	C5H11NO2	10026	Moderate		Inter Info	[3], [4]
D0087		Anisindione	C16H12O3	2197	Moderate		Inter Info	[3], [4]
D0092		Antithrombin Alfa	NA	NA	Moderate		Inter Info	[3], [4]
D0093		Antithrombin III human	NA	NA	Moderate		Inter Info	[3], [4]
D0096		Apixaban	C25H25N5O4	10182969	Moderate		Inter Info	[3], [4]
D1747		Beta carotene	C40H56	5280489	Moderate		Inter Info	[3]
D0176		Betrixaban	C23H22ClN5O3	10275777	Moderate		Inter Info	[3], [4]
D0194		Bosentan	C27H29N5O6S	104865	Moderate		Inter Info	[3], [4]
D0210		Bromfenac	C15H12BrNO3	60726	Moderate		Inter Info	[3], [4]
D0247		Cangrelor	C17H25Cl2F3N5O12P3S2	9854012	Moderate		Inter Info	[3], [4]
D0250		Caplacizumab	NA	NA	Moderate		Inter Info	[3], [4]
D0309		Chamomile	C15H10O5	5280443	Moderate		Inter Info	[3], [4]
D0363		Clonidine	C9H9Cl2N3	2803	Moderate		Inter Info	[3], [4]
D0364		Clopidogrel	C16H16ClNO2S	60606	Moderate		Inter Info	[3], [4]
D0396		Cyclandelate	C17H24O3	2893	Moderate		Inter Info	[3], [4]
D0414		Dalteparin	C26H42N2O37S5	772	Moderate		Inter Info	[3], [4]
D0435		Defibrotide	C20H21N4O6P	135565962	Moderate		Inter Info	[3], [4]
D0444		Deserpidine	C32H38N2O8	8550	Moderate		Inter Info	[3], [4]
D0474		Diazoxide	C8H7ClN2O2S	3019	Moderate		Inter Info	[3], [4]
D0476		Diclofenac	C14H11Cl2NO2	3033	Moderate		Inter Info	[3], [4]
D0489		Diflunisal	C13H8F2O3	3059	Moderate		Inter Info	[3], [4]
D0506		Dipyridamole	C24H40N8O4	3108	Moderate		Inter Info	[3], [4]
D0524		Doxazosin	C23H25N5O5	3157	Moderate		Inter Info	[3], [4]
D0551		Edoxaban	C24H30ClN7O4S	10280735	Moderate		Inter Info	[3], [4]
D0574		Enoxaparin	C26H42N2O37S5	772	Moderate		Inter Info	[3], [4]
D0586		Epoprostenol	C20H32O5	5282411	Moderate		Inter Info	[3], [4]
D0624		Etodolac	C17H21NO3	3308	Moderate		Inter Info	[3], [4]
D0644		Fenoldopam	C16H16ClNO3	3341	Moderate		Inter Info	[3], [4]
D0645		Fenoprofen	C15H14O3	3342	Moderate		Inter Info	[3], [4]
D0680		Flurbiprofen	C15H13FO2	3394	Moderate		Inter Info	[3], [4]
D0690		Fondaparinux	C31H53N3O49S8	5282448	Moderate		Inter Info	[3], [4]
D0711		Garlic	NA	NA	Moderate		Inter Info	[3], [4]
D0721		Ginger	C30H40O6	442138	Moderate		Inter Info	[3], [4]
D0722		Ginkgo biloba	NA	NA	Moderate		Inter Info	[3], [4]
D0723		Ginseng	C42H66O17	420552	Moderate		Inter Info	[3], [4]
D0742		Guanabenz	C8H8Cl2N4	5702063	Moderate		Inter Info	[3], [4]
D0744		Guanethidine	C10H22N4	3518	Moderate		Inter Info	[3], [4]
D0745		Guanfacine	C9H9Cl2N3O	3519	Moderate		Inter Info	[3], [4]
D0753		Heparin	C26H42N2O37S5	772	Moderate		Inter Info	[3], [4]
D0770		Hydralazine	C8H8N4	3637	Moderate		Inter Info	[3], [4]
D0786		Ibuprofen	C13H18O2	3672	Moderate		Inter Info	[3], [4]
D0792		Iloprost	C22H32O4	5311181	Moderate		Inter Info	[3], [4]
D0860		Isosorbide	C6H10O4	12597	Moderate		Inter Info	[3], [4]
D0861		Isosorbide dinitrate	C6H8N2O8	6883	Moderate		Inter Info	[3], [4]
D0862		Isosorbide mononitrate	C6H9NO6	27661	Moderate		Inter Info	[3], [4]
D0864		Isoxsuprine	C18H23NO3	3783	Moderate		Inter Info	[3], [4]
D0881		Ketoprofen	C16H14O3	3825	Moderate		Inter Info	[3], [4]
D0882		Ketorolac	C15H13NO3	3826	Moderate		Inter Info	[3], [4]
D0942		Lofexidine	C11H12Cl2N2O	30668	Moderate		Inter Info	[3], [4]
D0983		Mecamylamine	C11H21N	4032	Moderate		Inter Info	[3], [4]
D0988		Meclofenamic acid	C14H11Cl2NO2	4037	Moderate		Inter Info	[3], [4]
D0991		Mefenamic acid	C15H15NO2	4044	Moderate		Inter Info	[3], [4]
D0995		Meloxicam	C14H13N3O4S2	54677470	Moderate		Inter Info	[3], [4]
D1035		Methyldopa	C10H13NO4	38853	Moderate		Inter Info	[3], [4]
D1053		Metyrosine	C10H13NO3	441350	Moderate		Inter Info	[3], [4]
D1097		Nabumetone	C15H16O2	4409	Moderate		Inter Info	[3], [4]
D1109		Naproxen	C14H14O3	156391	Moderate		Inter Info	[3], [4]
D1146		Nitroglycerin	C3H5N3O9	4510	Moderate		Inter Info	[3], [4]
D1196		Oxaprozin	C18H15NO3	4614	Moderate		Inter Info	[3], [4]
D1223		Papaverine	C20H21NO4	4680	Moderate		Inter Info	[3], [4]
D1249		Pentosan polysulfate	C10H18O21S4	37720	Moderate		Inter Info	[3], [4]
D1267		Phenoxybenzamine	C18H22ClNO	4768	Moderate		Inter Info	[3], [4]
D1271		Phentolamine	C17H19N3O	5775	Moderate		Inter Info	[3], [4]
D1274		Phenylbutazone	C19H20N2O2	4781	Moderate		Inter Info	[3], [4]
D1328		Prasugrel	C20H20FNO3S	6918456	Moderate		Inter Info	[3], [4]
D1417		Rivaroxaban	C19H18ClN3O5S	9875401	Moderate		Inter Info	[3], [4]
D1466		Silodosin	C25H32F3N3O4	5312125	Moderate		Inter Info	[3], [4]
D1518		Sulfinpyrazone	C23H20N2O3S	5342	Moderate		Inter Info	[3], [4]
D1520		Sulindac	C20H17FO3S	1548887	Moderate		Inter Info	[3], [4]
D1527		Tadalafil	C22H19N3O4	110635	Moderate		Inter Info	[3], [4]
D1534		Tamsulosin	C20H28N2O5S	129211	Moderate		Inter Info	[3], [4]
D1552		Terazosin	C19H25N5O4	5401	Moderate		Inter Info	[3], [4]
D1579		Ticagrelor	C23H28F2N6O4S	9871419	Moderate		Inter Info	[3], [4]
D1588		Tinzaparin	C26H42N2O37S5	772	Moderate		Inter Info	[3], [4]
D1593		Tirofiban	C22H36N2O5S	60947	Moderate		Inter Info	[3], [4]
D1602		Tolazoline	C10H12N2	5504	Moderate		Inter Info	[3], [4]
D1606		Tolmetin	C15H15NO3	5509	Moderate		Inter Info	[3], [4]
D1643		Trimethaphan	C22H25N2OS+	23576	Moderate		Inter Info	[3], [4]
D1682		Vardenafil	C23H32N6O4S	135400189	Moderate		Inter Info	[3], [4]
D1705		Vorapaxar	C29H33FN2O4	10077130	Moderate		Inter Info	[3], [4]
D1711		Warfarin	C19H16O4	54678486	Moderate		Inter Info	[3], [4]

References
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2	Product Information. Gleolan (aminolevulinic acid). NX Development Corp, Lexington, KY.
3	Product Information. Visudyne (verteporfin) Valeant Pharmaceuticals, Costa Mesa, CA.
4	Product Information. Xatral (alfuzosin). Sanofi-Synthelabo Canada Inc, Markham, ON.
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8	Product Information. Metvixia (methyl aminolevulinate topical). Galderma Laboratories Inc, Cranbury, NJ.
9	Product Information. Oxsoralen (methoxsalen). ICN Pharmaceuticals Inc, Costa Mesa, CA.
10	Product Information. Uvadex (methoxsalen). Therakos Inc, Exton, PA.
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13	Product Information. Lucentis (ranibizumab ophthalmic). Genentech, South San Francisco, CA.
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