Details of Drug

Details of Drug

 Drug General Information (ID: D1571)
  Drug Name
Thiabendazole
  Drug Type Small molecule
  Drug Synonymous
Biogard; Bioguard; Bovizole; Cropasal; Drawipas; Eprofil; Equizole; Hymush; Lombristop; Mertec; Mertect; Mintesol; Mintezol; Mintezole; Minzolum; Mycozol; Nemacin; Nemapan; Omnizole; Ormogal; Pitrizet; Polival; RPH; Sistesan; Storite; Tbdz; Tebuzate; Tecto; Testo; Thiaben; Thiabendazol; Thiabendazolum; Thiabendole; Thiabenzazole; Thiabenzole; Thibendole; Thibenzol; Thibenzole; Thiprazole; Tiabenda; Tiabendazol; Tiabendazole; Tiabendazolum; Tobaz; Tresaderm; Triasox; Tubazole; Captan T; Equivet TZ; Equizole A; Helmindrax octelmin; Hokustar HP; Mertect lsp; RTU Flowable Fungicide; Tecto B; Tecto rph; Thibenzole att; Top Form Wormer; Chemviron TK 100; G 491; MK 360; Mertect 160; Mertect 340f; Metasol TK 100; Metasol tk 10; PS1057_SUPELCO; Sanaizol 100; Syntol M100; TBZ 6; TBZ 60W; Tecto 10P; Tecto 40F; Tecto 60; Thibenzole 200; Tibimix 20; APL-luster; Arbotect (TN); MK-360; Metasol TK-100; Mintezol (TN); TBZ-6; Thiabendazole (USP); Thiabendazole [BSI:ISO]; Thiabendazole [USAN:BAN]; Tiabendazolum [INN-Latin]; Tresaderm (TN); E-Z-Ex; Mintezol, Equizole, Thiabendazole; Tiabendazol [INN-Spanish, French]; Tiabendazole (JAN/INN); 2-(1,3-Thiazol-4-yl)-1H-benzimidazole; 2-(1,3-Thiazol-4-yl)benzimidazole; 2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole; 2-(4'-Thiazolyl)benzimidazole; 2-(4-Thiazolyl)-1H-benzimidazole; 2-(4-Thiazolyl)benzimidazole; 2-(Thiazol-4-yl)benzimidazole; 2-Thiazol-4-yl-1H-benzoimidazole; 2-Thiazole-4-ylbenzimidazole; 2-[4-Thiazoly]benzimidazole; 4-(1H-benzimidazol-2-yl)-1,3-thiazole; 4-(2-Benzimidazolyl)thiazole
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  Disease Class 1F90: Parasitic worm infestation; 8D64: Hydrocephalus
  Therapeutic Class Antinematodal Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C10H7N3S
  InChI 1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)
  InChIKey WJCNZQLZVWNLKY-UHFFFAOYSA-N
  Canonical SMILES C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3
  External Link
Pubchem ID 5430
CAS Number 148-79-8
CHEBI ID 45979
TTD ID D08QCJ
INTEDE ID DR1578
VARIDT ID DR00867

Drug-Drug Interaction Network
  Sunburst Graph
AM002  Affected cellular transport
AM003  Affected organization distribution
AM004  Affected intra/extra-hepatic metabolism
BM010  Transporter inhibition
BM014  Interference of cell/tissue uptake
BM017  CYP450 enzyme inhibition
BM022  CYP450 enzyme induction
BM025  Decreased metabolism (Unspecific)
  Relation Graph
 Full list of drugs interacting with Thiabendazole
      Affected cellular transport
      Affected organization distribution
   Interference of cell/tissue uptake Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1822
 
Iodide I-123
 
I-
 
135300 
Moderate    Inter Info   
[44], [45], [46]
      Affected intra/extra-hepatic metabolism
   CYP450 enzyme inhibition Drug Num:  32
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1385
 
Rasagiline
 
C12H13N
 
3052776 
Major    Inter Info   
[1], [2], [3]
D1596
 
Tizanidine
 
C9H8ClN5S
 
5487 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11]
D0084
 
Anagrelide
 
C10H7Cl2N3O
 
135409400 
Moderate    Inter Info   
[12]
D0231
 
Caffeine
 
C8H10N4O2
 
2519 
Moderate    Inter Info   
[13]
D0324
 
Chlorpromazine
 
C17H19ClN2S
 
2726 
Moderate    Inter Info   
[1], [2], [14]
D0535
 
Droperidol
 
C22H22FN3O2
 
3168 
Moderate    Inter Info   
[15], [16], [1], [2], [17], [18], [19]
D0539
 
Duloxetine
 
C18H19NOS
 
60835 
Moderate    Inter Info   
[20], [21], [22], [23]
D0740
 
Grepafloxacin
 
C19H22FN3O3
 
72474 
Moderate    Inter Info   
[24]
D1075
 
Mirtazapine
 
C17H19N3
 
4205 
Moderate    Inter Info   
[25], [26], [27], [28], [29]
D1427
 
Ropinirole
 
C16H24N2O
 
5095 
Moderate    Inter Info   
[30], [31]
D0002
 
Abametapir (topical)
 
C12H12N2
 
15664 
Moderate    Inter Info   
[36]
D0043
 
Alosetron
 
C17H18N4O
 
2099 
Moderate    Inter Info   
[37]
D0112
 
Asenapine
 
C17H16ClNO
 
3036780 
Moderate    Inter Info   
[38]
D0157
 
Bendamustine
 
C16H21Cl2N3O2
 
65628 
Moderate    Inter Info   
[39]
D0251
 
Capmatinib
 
C23H17FN6O
 
25145656 
Moderate    Inter Info   
[40]
D0432
 
Deferasirox
 
C21H15N3O4
 
214348 
Moderate    Inter Info   
[41]
D0545
 
Echinacea
 
NA
 
NA
Moderate    Inter Info   
[42]
D0724
 
Givosiran
 
C78H139N11O30
 
119058042 
Moderate    Inter Info   
[43]
D0916
 
Levobupivacaine
 
C18H28N2O
 
92253 
Moderate    Inter Info   
[2], [47]
D1160
 
Obeticholic acid
 
C26H44O4
 
447715 
Moderate    Inter Info   
[48]
D1189
 
Osilodrostat
 
C13H10FN3
 
44139752 
Moderate    Inter Info   
[50]
D1251
 
Pentoxifylline
 
C13H18N4O3
 
4740 
Moderate    Inter Info   
[51], [52]
D1292
 
Pimozide
 
C28H29F2N3O
 
16362 
Moderate    Inter Info   
[53], [54]
D1299
 
Pirfenidone
 
C12H11NO
 
40632 
Moderate    Inter Info   
[2], [55]
D1312
 
Pomalidomide
 
C13H11N3O4
 
134780 
Moderate    Inter Info   
[1], [2], [56]
D1378
 
Ramelteon
 
C16H21NO2
 
208902 
Moderate    Inter Info   
[57]
D1422
 
Roflumilast
 
C17H14Cl2F2N2O3
 
449193 
Moderate    Inter Info   
[2], [58], [59]
D1432
 
Rucaparib
 
C19H18FN3O
 
9931954 
Moderate    Inter Info   
[49]
D1505
 
Stiripentol
 
C14H18O3
 
5311454 
Moderate    Inter Info   
[2], [60], [61]
D1536
 
Tasimelteon
 
C15H19NO2
 
10220503 
Moderate    Inter Info   
[62]
D1687
 
Vemurafenib
 
C23H18ClF2N3O3S
 
42611257 
Moderate    Inter Info   
[11]
D1728
 
Zolmitriptan
 
C16H21N3O2
 
60857 
Moderate    Inter Info   
[2], [64]
   CYP450 enzyme induction Drug Num:  2
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1167
 
Olaparib
 
C24H23FN4O3
 
23725625 
Moderate    Inter Info   
[1], [2], [49]
D1556
 
Teriflunomide
 
C12H9F3N2O2
 
54684141 
Moderate    Inter Info   
[1], [2], [63]
   Decreased metabolism (Unspecific) Drug Num:  3
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1570
 
Theophylline
 
C7H8N4O2
 
2153 
Moderate    Inter Info   
[32], [33], [34], [35]
D0064
 
Aminophylline
 
C16H24N10O4
 
9433 
Moderate    Inter Info   
[32], [33], [34], [35]
D1201
 
Oxtriphylline
 
C12H21N5O3
 
656652 
Moderate    Inter Info   
[32], [33], [34]
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