Details of Drug

Details of Drug

 Drug General Information (ID: D1338)
  Drug Name
Prilocaine (topical)
  Drug Type Small molecule
  Drug Synonymous
Citanest; Prilocaina; Prilocainum; Propitocaine; Prilocaine [USAN]; Prilocaine base; Astra 1512; Astra 1515; L 67; Citanest (TN); Prilocaina [INN-Spanish]; Prilocainum [INN-Latin]; Propitocaine (JAN); Prilocaine (USP/INN); O-Methyl-2-propylaminopropionanilide; O-Methyl-alpha-propylaminopropionanilide; Alpha-n-Propylamino-2-methylpropionanilide; N-[2-Methylphenyl]-2-[propylamino]propanamide; N-(2-methylphenyl)-N2-propylalaninamide; N-(2-Methylphenyl)-2-(propylamino)propanamide; N-(2-methylphenyl)-N(2)-propylalaninamide; Propanamide, N-(2-methylphenyl)-2-(propylamino)-(9CI); 2-(Propylamino)-o-propionotoluidide; 2-Methyl-.alpha.-propylaminopropionanilide; 2-Methyl-alpha-propylaminopropionanilide
    Click to Show/Hide
  Disease Class MG30-MG3Z: Pain
  Therapeutic Class Anesthetics
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C13H20N2O
  InChI 1S/C13H20N2O/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2/h5-8,11,14H,4,9H2,1-3H3,(H,15,16)
  InChIKey MVFGUOIZUNYYSO-UHFFFAOYSA-N
  Canonical SMILES CCCNC(C)C(=O)NC1=CC=CC=C1C
  External Link
Pubchem ID 4906
CAS Number 721-50-6
CHEBI ID 8404
TTD ID D06LYG

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
BM071  Increased risk of methemoglobinemia
  Relation Graph
 Full list of drugs interacting with Prilocaine (topical)
      Pharmacodynamic additive effects
   Increased risk of methemoglobinemia Drug Num:  26
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0011
 
Acetaminophen
 
C8H9NO2
 
1983 
Major    Inter Info   
[1], [2], [3]
D0218
 
Bupivacaine
 
C18H28N2O
 
2474 
Major    Inter Info   
[1], [2], [3]
D0320
 
Chloroquine
 
C18H26ClN3
 
2719 
Major    Inter Info   
[1], [2], [3]
D0419
 
Dapsone
 
C12H12N2O2S
 
2955 
Major    Inter Info   
[1], [2], [3]
D0682
 
Flutamide
 
C11H11F3N2O3
 
3397 
Major    Inter Info   
[1], [2], [3]
D0927
 
Lidocaine
 
C14H22N2O
 
3676 
Major    Inter Info   
[1], [2], [3]
D0928
 
Lidocaine (topical)
 
C14H22N2O
 
3676 
Major    Inter Info   
[1], [2], [3]
D1145
 
Nitrofurantoin
 
C8H6N4O5
 
6604200 
Major    Inter Info   
[1], [2], [3]
D1146
 
Nitroglycerin
 
C3H5N3O9
 
4510 
Major    Inter Info   
[1], [2], [3]
D1147
 
Nitroprusside
 
C5FeN6O
 
11953891 
Major    Inter Info   
[1], [2], [3]
D1283
 
Phenytoin
 
C15H12N2O2
 
1775 
Major    Inter Info   
[1], [2], [3]
D0083
 
Amyl Nitrite
 
C5H11NO2
 
10026 
Major    Inter Info   
[1], [2], [3]
D0860
 
Isosorbide
 
C6H10O4
 
12597 
Major    Inter Info   
[1], [2], [3]
D0861
 
Isosorbide dinitrate
 
C6H8N2O8
 
6883 
Major    Inter Info   
[1], [2], [3]
D0862
 
Isosorbide mononitrate
 
C6H9NO6
 
27661 
Major    Inter Info   
[1], [2], [3]
D1046
 
Metoclopramide
 
C14H22ClN3O2
 
4168 
Major    Inter Info   
[1], [2], [3]
D1261
 
Phenazopyridine
 
C11H11N5
 
4756 
Major    Inter Info   
[1], [2], [3]
D1265
 
Phenobarbital
 
C12H12N2O3
 
4763 
Major    Inter Info   
[1], [2], [3]
D1339
 
Primaquine
 
C15H21N3O
 
4908 
Major    Inter Info   
[1], [2], [3]
D1514
 
Sulfadoxine
 
C12H14N4O4S
 
17134 
Major    Inter Info   
[1], [2], [3]
D1516
 
Sulfamethoxazole
 
C10H11N3O3S
 
5329 
Major    Inter Info   
[1], [2], [3]
D1517
 
Sulfasalazine
 
C18H14N4O5S
 
5339 
Major    Inter Info   
[1], [2], [3]
D1372
 
Quinine
 
C20H24N2O2
 
3034034 
Major    Inter Info   
[1], [2], [3]
D1513
 
Sulfadiazine
 
C10H10N4O2S
 
5215 
Major    Inter Info   
[1], [2], [3]
D1515
 
Sulfamethizole
 
C9H10N4O2S2
 
5328 
Major    Inter Info   
[1], [2], [3]
D1519
 
Sulfisoxazole
 
C11H13N3O3S
 
5344 
Major    Inter Info   
[1], [2], [3]
References
1 Canadian Pharmacists Association.
2 Cerner Multum, Inc. "Australian Product Information.".
3 Skold A, Cosco DL, Klein R "Methemoglobinemia: pathogenesis, diagnosis, and management." South Med J 104 (2011): 757-61. [PMID: 22024786]