Details of Drug

Details of Drug

 Drug General Information (ID: D1327)
  Drug Name
Prasterone enantate
  Drug Type Small molecule
  Drug Synonymous
23983-43-9; Dehydroepiandrosterone enanthate; Prasterone enanthate; UNII-2W8I1S6T5L; 2W8I1S6T5L; [(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] heptanoate; Androst-5-en-17-one, 3-[(1-oxoheptyl)oxy]-, (3b)-; DHEA enanthate; DHEA oenanthate; Prasterone enantate; Dehydroepiandrosterone oenanthate; EINECS 245-970-8; 3beta-Heptanoyloxy-5-androsten-17-one; 3beta-Hydroxyandrost-5-en-17-one heptanoate; SCHEMBL2453080; (3S,8R,9S,10R,13S,14S)-10,13-Dimethyl-17-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl heptanoate; BCP10784; ZINC5820240; AKOS025310707; 5-Androsten-3beta-ol-17-one enanthate; DS-13434; 3beta-(1-Oxoheptyloxy)androst-5-en-17-one; 983A439; Q27255695
    Click to Show/Hide
  Therapeutic Class Androgens
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C26H40O3
  InChI InChI=1S/C26H40O3/c1-4-5-6-7-8-24(28)29-19-13-15-25(2)18(17-19)9-10-20-21-11-12-23(27)26(21,3)16-14-22(20)25/h9,19-22H,4-8,10-17H2,1-3H3/t19-,20-,21-,22-,25-,26-/m0/s1
  InChIKey HHENOUDBWKNPAB-BNCSLUSBSA-N
  Canonical SMILES CCCCCCC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CCC4=O)C)C
  External Link
Pubchem ID 163331

Drug-Drug Interaction Network
  Sunburst Graph
AM004  Affected intra/extra-hepatic metabolism
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM017  CYP450 enzyme inhibition
BM019  UGT inhibition
BM047  Additive thrombogenic effects
BM055  Increased risk of hepatotoxicity
BM107  Attenuated pharmacological effects (Unspecific)
BM108  Increased risk of hypercalcemia
  Relation Graph
 Full list of drugs interacting with Prasterone enantate
      Affected intra/extra-hepatic metabolism
   CYP450 enzyme inhibition Drug Num:  5
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0045
 
Alprazolam
 
C17H13ClN4
 
2118 
Minor    Inter Info   
[43], [44], [45]
D0473
 
Diazepam
 
C16H13ClN2O
 
3016 
Minor    Inter Info   
[43], [44], [45]
D0994
 
Melatonin
 
C13H16N2O2
 
896 
Minor    Inter Info   
[2], [27], [28]
D1060
 
Midazolam
 
C18H13ClFN3
 
4192 
Minor    Inter Info   
[43], [44], [45]
D1632
 
Triazolam
 
C17H12Cl2N4
 
5556 
Minor    Inter Info   
[43], [44], [45]
   UGT inhibition Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1227
 
Paritaprevir
 
C40H43N7O7S
 
45110509 
Major    Inter Info   
[9], [10]
      Pharmacodynamic additive effects
   Additive thrombogenic effects Drug Num:  3
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0261
 
Carfilzomib
 
C40H57N5O7
 
11556711 
Major    Inter Info   
[1], [2], [3]
D0385
 
Conestat alfa
 
NA
 
NA
Moderate    Inter Info   
[21], [22], [23]
D0762
 
Human C1-esterase inhibitor
 
NA
 
NA
Moderate    Inter Info   
[21], [22], [23]
   Increased risk of hepatotoxicity Drug Num:  24
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0900
 
Leflunomide
 
C12H9F3N2O2
 
3899 
Major    Inter Info   
[4], [5], [6]
D0944
 
Lomitapide
 
C39H37F6N3O2
 
9853053 
Major    Inter Info   
[7]
D1073
 
Mipomersen
 
C230H324N67O122P19S19
 
118984467 
Major    Inter Info   
[8]
D1258
 
Pexidartinib
 
C20H15ClF3N5
 
25151352 
Major    Inter Info   
[11]
D1556
 
Teriflunomide
 
C12H9F3N2O2
 
54684141 
Major    Inter Info   
[4], [5], [6]
D0113
 
Asparaginase Erwinia chrysanthemi
 
NA
 
NA
Moderate    Inter Info   
[12], [2], [13]
D0114
 
Asparaginase Escherichia coli
 
NA
 
NA
Moderate    Inter Info   
[12], [2], [13]
D0149
 
Bedaquiline
 
C32H31BrN2O2
 
5388906 
Moderate    Inter Info   
[14], [15]
D0199
 
Brentuximab vedotin
 
NA
 
NA
Moderate    Inter Info   
[16]
D0232
 
Calaspargase pegol
 
NA
 
NA
Moderate    Inter Info   
[12], [2], [13]
D0248
 
Cannabidiol
 
C21H30O2
 
644019 
Moderate    Inter Info   
[3], [19]
D0357
 
Clofarabine
 
C10H11ClFN5O3
 
119182 
Moderate    Inter Info   
[20]
D0554
 
Efavirenz
 
C14H9ClF3NO2
 
64139 
Moderate    Inter Info   
[24], [25]
D0584
 
Epirubicin
 
C27H29NO11
 
41867 
Moderate    Inter Info   
[2], [3], [29]
D0789
 
Idelalisib
 
C22H18FN7O
 
11625818 
Moderate    Inter Info   
[14], [30]
D0826
 
Interferon beta-1a
 
NA
 
NA
Moderate    Inter Info   
[31], [32], [33]
D0827
 
Interferon beta-1b
 
NA
 
NA
Moderate    Inter Info   
[31], [32], [33]
D1025
 
Methotrexate
 
C20H22N8O5
 
126941 
Moderate    Inter Info   
[3], [34], [35]
D1106
 
Naltrexone
 
C20H23NO4
 
5360515 
Moderate    Inter Info   
[36]
D1234
 
Pegaspargase
 
C14H19NO
 
436058 
Moderate    Inter Info   
[12], [2], [13]
D1239
 
Peginterferon beta-1a
 
NA
 
NA
Moderate    Inter Info   
[31], [32], [33]
D1389
 
Remdesivir
 
C27H35N6O8P
 
121304016 
Moderate    Inter Info   
[37], [38], [39]
D1589
 
Tioguanine
 
C5H5N5S
 
2723601 
Moderate    Inter Info   
[40], [41]
D1615
 
Trabectedin
 
C39H43N3O11S
 
108150 
Moderate    Inter Info   
[3], [42]
   Increased risk of hypercalcemia Drug Num:  2
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1753
 
Calcipotriol (topical)
 
C27H40O3
 
5288783 
Moderate    Inter Info   
[17], [18]
D1754
 
Calcitriol (topical)
 
C27H44O3
 
5280453 
Moderate    Inter Info   
[17], [18]
      Pharmacodynamic antagonistic effects
   Attenuated pharmacological effects (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0555
 
Elagolix
 
C32H30F5N3O5
 
11250647 
Moderate    Inter Info   
[26], [27], [28]
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