Details of Drug

Details of Drug

 Drug General Information (ID: D0706)
  Drug Name
Gadoxetic acid
  Drug Type Small molecule
  Drug Synonymous
Gadoxetic acid; Gd-EOB-DTPA; gadoxetate; UNII-3QJA87N40S; 135326-11-3; 2-[[(2S)-2-[bis(carboxylatomethyl)amino]-3-(4-ethoxyphenyl)propyl]-[2-[bis(carboxylatomethyl)amino]ethyl]amino]acetate;gadolinium(3+);hydron; Gadoxetic acid [INN]; Primovist; 3QJA87N40S; Dihydrogen (N((2s)-2-(bis(carboxymethyl)amino)-3-(p-ethoxyphenyl)propyl)-N-(2-(bis(carboxymethyl)amino)ethyl)glycinato(5-)gadolinate(2-).; Dihydrogen (N-((2S)-2-(bis(carboxymethyl)amino)-3-(p-ethoxyphenyl)propyl)-N-(2-(bis(carboxymethyl)amino)ethyl)glycinato(5-))gadolinate(2-)
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  Therapeutic Class Mri Contrast Media
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C23H30GdN3O11
  InChI InChI=1S/C23H33N3O11.Gd/c1-2-37-18-5-3-16(4-6-18)9-17(26(14-22(33)34)15-23(35)36)10-24(11-19(27)28)7-8-25(12-20(29)30)13-21(31)32;/h3-6,17H,2,7-15H2,1H3,(H,27,28)(H,29,30)(H,31,32)(H,33,34)(H,35,36);/q;+3/p-3/t17-;/m0./s1
  InChIKey PCZHWPSNPWAQNF-LMOVPXPDSA-K
  Canonical SMILES [H+].[H+].CCOC1=CC=C(C=C1)C[C@@H](CN(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[Gd+3]
  External Link
Pubchem ID 56841043

Drug-Drug Interaction Network
  Sunburst Graph
AM005  Affected excretion pathways
BM028  Competitive inhibition of renal tubular secretion
  Relation Graph
 Full list of drugs interacting with Gadoxetic acid
      Affected excretion pathways
   Competitive inhibition of renal tubular secretion Drug Num:  3
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1399
 
Rifabutin
 
C46H62N4O11
 
135398743 
Moderate    Inter Info   
[1]
D1400
 
Rifampicin
 
C43H58N4O12
 
135398735 
Moderate    Inter Info   
[1]
D1401
 
Rifapentine
 
C47H64N4O12
 
135403821 
Moderate    Inter Info   
[1]
References
1 Product Information. Eovist (gadoxetate). Bayer Pharmaceutical Inc, West Haven, CT.